Cryo-EM structure of neutralizing antibody 8G3 in complex with BA.1 RBD
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 9js4
Q-score: 0.434
Liao Y, Ma H, Wang Z, Wang S, He Y, Chang Y, Zong H, Tang H, Wang L, Ke Y, Cai H, Li P, Tang J, Chen H, Drelich A, Peng BH, Hsu J, Tat V, Tseng CK, Song J, Yuan Y, Wu M, Liu J, Yue Y, Zhang X, Wang Z, Yang L, Li J, Ni X, Li H, Xiang Y, Bian Y, Zhang B, Yin H, Dimitrov DS, Gilly J, Han L, Jiang H, Xie Y, Zhu J
PNAS (2025) 122 pp. e2406659122-e2406659122 [ Pubmed: 39908098 DOI: doi:10.1073/pnas.2406659122 ]
- Cryo-em structure of neutralizing antibody 8g3 in complex with ba.1 rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (137 kDa, Protein from Severe acute respiratory syndrome coronavirus)
- Heavy chain of 8g3 (23 kDa, Protein from Homo heidelbergensis)
- Light chain of 8g3 (23 kDa, Protein from Homo sapiens)
To Be Published
Human ACE2 binding the complex of Omicron BA.1 6p spike protein and W328-6H2 IgG
To Be Published
- W328-6h2 igg (Complex from Homo sapiens)
- Ace2 (Complex from Homo sapiens)
- Human ace2 binding the complex of omicron ba.1 6p spike protein and w328-6h2 igg (Complex from Homo sapiens)
- Severe acute respiratory syndrome coronavirus 2 omicron ba.1 6p (Complex from Severe acute respiratory syndrome coronavirus 2)
Cryo-EM structure of Omicron BA.1 RBD in complex with W328-6H2 (local refinement)
Resolution: 3.96 Å
EM Method: Single-particle
Fitted PDBs: 8jam
Q-score: 0.374
To Be Published
SARS-CoV-2 spike omicron (BA.1) ectodomain trimer in complex with SC27 Fab, global refinement
Voss WN, Mallory MA, Byrne PO, Marchioni JM, Knudson SA, Powers JM, Leist SR, Dadonaite B, Townsend DR, Kain J, Huang Y, Satterwhite E, Castillo IN, Mattocks M, Paresi C, Munt JE, Scobey T, Seeger A, Premkumar L, Bloom JD, Georgiou G, McLellan JS, Baric RS, Lavinder JJ, Ippolito GC
Cell Rep Med (2024) 5 pp. 101668-101668 [ Pubmed: 39094579 DOI: doi:10.1016/j.xcrm.2024.101668 ]
Voss WN, Mallory MA, Byrne PO, Marchioni JM, Knudson SA, Powers JM, Leist SR, Dadonaite B, Townsend DR, Kain J, Huang Y, Satterwhite E, Castillo IN, Mattocks M, Paresi C, Munt JE, Scobey T, Seeger A, Premkumar L, Bloom JD, Georgiou G, McLellan JS, Baric RS, Lavinder JJ, Ippolito GC
Cell Rep Med (2024) 5 pp. 101668-101668 [ Pubmed: 39094579 DOI: doi:10.1016/j.xcrm.2024.101668 ]
Cryo-EM structure of the BA1-bound BRS3-Gq complex
Li C, Xu Y, Su W, He X, Li J, Li X, Xu HE, Yin W
Cell Rep (2024) 43 pp. 114511-114511 [ DOI: doi:10.1016/j.celrep.2024.114511 Pubmed: 39024101 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Bombesin receptor subtype-3 (40 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(q) subunit alpha (41 kDa, Protein from Homo sapiens)
- Ba1 (1 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Ba1-brs3-gq complex (Complex from Homo sapiens)
Structure of SARS-CoV-2 Omicron BA.1 Spike complexed with antibody PW5-570
Zhao X, Qiu T, Huang X, Mao Q, Wang Y, Qiao R, Li J, Mao T, Wang Y, Cun Y, Wang C, Luo C, Yoon C, Wang X, Li C, Cui Y, Zhao C, Li M, Chen Y, Cai G, Geng W, Hu Z, Cao J, Zhang W, Cao Z, Chu H, Sun L, Wang P
Cell Discov (2024) 10 pp. 14-14 [ DOI: doi:10.1038/s41421-024-00648-1 Pubmed: 38320990 ]
- Pw5-570 heavy chain (49 kDa, Protein from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Pw5-570 light chain (23 kDa, Protein from Homo sapiens)
- Ba.1 spike protein (s) trimer in complex with broadly neutralizing antibody pw5-570 (Complex from Severe acute respiratory syndrome coronavirus 2)