Structure of beta-arrestin1 in complex with C3aRpp
Resolution: 3.94 Å
EM Method: Single-particle
Fitted PDBs: 8ja3
Q-score: 0.327
Maharana J, Sano FK, Sarma P, Yadav MK, Duan L, Stepniewski TM, Chaturvedi M, Ranjan A, Singh V, Saha S, Mahajan G, Chami M, Shihoya W, Selent J, Chung KY, Banerjee R, Nureki O, Shukla AK
Science (2024) 383 pp. 101-108 [ DOI: doi:10.1126/science.adj3347 Pubmed: 38175886 ]
- Beta-arrestin-1 (40 kDa, Protein from Rattus norvegicus)
- Fab30 heavy chain (25 kDa, Protein from Mus musculus)
- Phosphopeptide derived from the c-terminal tail of c3ar receptor (c3arpp) (Complex from Homo sapiens)
- Fab30 heavy chain (Complex from Mus musculus)
- Beta-arrestin1 in complex with c3arpp (Complex)
- Beta-arrestin-1 (Complex from Rattus norvegicus)
- C3a anaphylatoxin chemotactic receptor (1 kDa, Protein from Homo sapiens)
- Fab30 light chain (23 kDa, Protein from Mus musculus)
- Fab30 light chain (Complex from Mus musculus)
Structure of EP54-C3aR-Go complex
Resolution: 2.88 Å
EM Method: Single-particle
Fitted PDBs: 8i95
Q-score: 0.561
Yadav MK, Maharana J, Yadav R, Saha S, Sarma P, Soni C, Singh V, Saha S, Ganguly M, Li XX, Mohapatra S, Mishra S, Khant HA, Chami M, Woodruff TM, Banerjee R, Shukla AK, Gati C
Cell (2023) 186 pp. 4956-4973.e21 [ Pubmed: 37852260 DOI: doi:10.1016/j.cell.2023.09.020 ]
- Ep54 ligand (1 kDa, Protein from Homo sapiens)
- Structure of ep54-c3ar-go complex (Complex)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (Complex from Homo sapiens)
- C3a anaphylatoxin chemotactic receptor (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (Complex from Homo sapiens)
- Antibody fragment - scfv16 (Complex from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Antibody fragment - scfv16 (26 kDa, Protein from Mus musculus)
- Ep54 ligand (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(o) subunit alpha (28 kDa, Protein from Homo sapiens)
- C3a anaphylatoxin chemotactic receptor (59 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(o) subunit alpha (Complex from Homo sapiens)
Structure of Apo-C3aR-Go complex (Glacios)
Resolution: 3.19 Å
EM Method: Single-particle
Fitted PDBs: 8i97
Q-score: 0.5
Yadav MK, Maharana J, Yadav R, Saha S, Sarma P, Soni C, Singh V, Saha S, Ganguly M, Li XX, Mohapatra S, Mishra S, Khant HA, Chami M, Woodruff TM, Banerjee R, Shukla AK, Gati C
Cell (2023) 186 pp. 4956-4973.e21 [ Pubmed: 37852260 DOI: doi:10.1016/j.cell.2023.09.020 ]
- Structure of apo-c3ar-go complex (glacios) (Complex)
- C3a anaphylatoxin chemotactic receptor (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (Complex from Homo sapiens)
- Antibody fragment - scfv16 (Complex from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Antibody fragment - scfv16 (26 kDa, Protein from Mus musculus)
- Guanine nucleotide-binding protein g(o) subunit alpha (28 kDa, Protein from Homo sapiens)
- C3a anaphylatoxin chemotactic receptor (59 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(o) subunit alpha (Complex from Homo sapiens)
Structure of EP54-C3aR-Gq complex
Resolution: 3.57 Å
EM Method: Single-particle
Fitted PDBs: 8i9a
Q-score: 0.431
Yadav MK, Maharana J, Yadav R, Saha S, Sarma P, Soni C, Singh V, Saha S, Ganguly M, Li XX, Mohapatra S, Mishra S, Khant HA, Chami M, Woodruff TM, Banerjee R, Shukla AK, Gati C
Cell (2023) 186 pp. 4956-4973.e21 [ Pubmed: 37852260 DOI: doi:10.1016/j.cell.2023.09.020 ]
- Ep54 ligand (1 kDa, Protein from Homo sapiens)
- C3a anaphylatoxin chemotactic receptor (59 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (Complex from Homo sapiens)
- C3a anaphylatoxin chemotactic receptor (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(q) subunit alpha (43 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (Complex from Homo sapiens)
- Antibody fragment - scfv16 (Complex from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Antibody fragment - scfv16 (26 kDa, Protein from Mus musculus)
- Ep54 ligand (Complex from Homo sapiens)
- Structure of ep54-c3ar-gq complex (Complex)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(q) subunit alpha (Complex from Homo sapiens)
Structure of C3a-C3aR-Go complex (Composite map)
Resolution: 3.18 Å
EM Method: Single-particle
Fitted PDBs: 8i9l
Q-score: 0.468
Yadav MK, Maharana J, Yadav R, Saha S, Sarma P, Soni C, Singh V, Saha S, Ganguly M, Li XX, Mohapatra S, Mishra S, Khant HA, Chami M, Woodruff TM, Banerjee R, Shukla AK, Gati C
Cell (2023) 186 pp. 4956-4973.e21 [ Pubmed: 37852260 DOI: doi:10.1016/j.cell.2023.09.020 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (Complex from Homo sapiens)
- C3a anaphylatoxin chemotactic receptor (Complex from Homo sapiens)
- Structure of c3a-c3ar-go complex (Complex)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (Complex from Homo sapiens)
- Antibody fragment - scfv16 (Complex from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Antibody fragment - scfv16 (26 kDa, Protein from Mus musculus)
- C3a anaphylatoxin (9 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(o) subunit alpha (28 kDa, Protein from Homo sapiens)
- C3a anaphylatoxin chemotactic receptor (59 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- C3a ligand (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(o) subunit alpha (Complex from Homo sapiens)
Structure of Apo-C3aR-Go complex (Titan)
Resolution: 3.26 Å
EM Method: Single-particle
Fitted PDBs: 8i9s
Q-score: 0.458
Yadav MK, Maharana J, Yadav R, Saha S, Sarma P, Soni C, Singh V, Saha S, Ganguly M, Li XX, Mohapatra S, Mishra S, Khant HA, Chami M, Woodruff TM, Banerjee R, Shukla AK, Gati C
Cell (2023) 186 pp. 4956-4973.e21 [ Pubmed: 37852260 DOI: doi:10.1016/j.cell.2023.09.020 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (Complex from Homo sapiens)
- C3a anaphylatoxin chemotactic receptor (Complex from Homo sapiens)
- Structure of apo-c3ar-go complex (titan) (Complex)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (Complex from Homo sapiens)
- Antibody fragment - scfv16 (Complex from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Antibody fragment - scfv16 (26 kDa, Protein from Mus musculus)
- Guanine nucleotide-binding protein g(o) subunit alpha (28 kDa, Protein from Homo sapiens)
- C3a anaphylatoxin chemotactic receptor (59 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(o) subunit alpha (Complex from Homo sapiens)
Structure of EP141-C3aR-Go complex
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8j6d
Q-score: 0.461
Yadav MK, Maharana J, Yadav R, Saha S, Sarma P, Soni C, Singh V, Saha S, Ganguly M, Li XX, Mohapatra S, Mishra S, Khant HA, Chami M, Woodruff TM, Banerjee R, Shukla AK, Gati C
Cell (2023) 186 pp. 4956-4973.e21 [ Pubmed: 37852260 DOI: doi:10.1016/j.cell.2023.09.020 ]
- Structure of ep141-c3ar-go complex (Complex from Homo sapiens)
- Ep141 peptide agonist (1 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Antibody fragment - scfv16 (26 kDa, Protein from Mus musculus)
- Guanine nucleotide-binding protein g(o) subunit alpha (28 kDa, Protein from Homo sapiens)
- C3a anaphylatoxin chemotactic receptor (59 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)