FSHR-Follicle stimulating hormone-compound 716340-Gs complex
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8i2g
Q-score: 0.363
Duan J, Xu P, Zhang H, Luan X, Yang J, He X, Mao C, Shen DD, Ji Y, Cheng X, Jiang H, Jiang Y, Zhang S, Zhang Y, Xu HE
Nat Commun (2023) 14 pp. 519-519 [ DOI: doi:10.1038/s41467-023-36170-3 Pubmed: 36720854 ]
- Palmitic acid (256 Da, Ligand)
- Fshr-follicle stimulating hormone-compound 716340-gs complex (Complex from Homo sapiens)
- Follicle-stimulating hormone receptor (76 kDa, Protein from Homo sapiens)
- Glycoprotein hormones alpha chain (10 kDa, Protein from Homo sapiens)
- Nb35 (13 kDa, Protein from Lama glama)
- Cholesterol (386 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- N-tert-butyl-n-ethyl-8-methoxy-9-propan-2-yloxy-1-thiophen-2-yl-5,6-dihydroimidazo[5,1-a]isoquinoline-3-carboxamide (467 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Myristic acid (228 Da, Ligand)
- Follitropin subunit beta (12 kDa, Protein from Homo sapiens)
- Chimera of guanine nucleotide-binding protein g(s) subunit alpha and guanine nucleotide-binding protein g(s) subunit alpha isoforms xlas (30 kDa, Protein from Homo sapiens)
Galanin-bound galanin receptor 1 in complex with Gi
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 7wq3
Q-score: 0.312
Duan J, Shen DD, Zhao T, Guo S, He X, Yin W, Xu P, Ji Y, Chen LN, Liu J, Zhang H, Liu Q, Shi Y, Cheng X, Jiang H, Eric Xu H, Zhang Y, Xie X, Jiang Y
Nat Commun (2022) 13 pp. 1364- [ DOI: doi:10.1038/s41467-022-29072-3 ]
- Galanin receptor type 1 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (Complex from Rattus)
- Galanin-gal1r-gi-scfv16 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (Complex from Bos taurus)
- Scfv16 (26 kDa, Protein from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- Scfv16 (Complex)
- Cholesterol (386 Da, Ligand)
- Galanin (Complex)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Rattus)
- Galanin receptor type 1 (38 kDa, Protein from Homo sapiens)
- Galanin (3 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (Complex from Mus musculus)
Galanin-bound galanin receptor 2 in complex with Gq
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 7wq4
Q-score: 0.528
Duan J, Shen DD, Zhao T, Guo S, He X, Yin W, Xu P, Ji Y, Chen LN, Liu J, Zhang H, Liu Q, Shi Y, Cheng X, Jiang H, Eric Xu H, Zhang Y, Xie X, Jiang Y
Nat Commun (2022) 13 pp. 1364- [ DOI: doi:10.1038/s41467-022-29072-3 ]
- Nb35 (14 kDa, Protein from Lama glama)
- Galanin (Complex from Homo sapiens)
- Galanin receptor type 2 (41 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Rattus)
- Nb35 (Complex from Bos taurus)
- Engineered guanine nucleotide-binding protein g(q) subunit alpha (Complex from Rattus)
- Galanin-gal2r-gq-nb35 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- Cholesterol (386 Da, Ligand)
- Galanin receptor type 2 (Complex)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (Complex from Lama glama)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (Complex)
- Galanin (3 kDa, Protein from Homo sapiens)
- Engineered guanine nucleotide-binding protein g(q) subunit alpha (41 kDa, Protein from Homo sapiens)
cryo-EM structure of LTB4-bound BLT1 in complex with Gi protein
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7vkt
Q-score: 0.544
Wang N, He X, Zhao J, Jiang H, Cheng X, Xia Y, Eric Xu H, He Y
Nat Commun (2022) 13 pp. 1156-1156 [ DOI: doi:10.1038/s41467-022-28820-9 Pubmed: 35241677 ]
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Leukotriene b4 receptor 1 (37 kDa, Protein from Homo sapiens)
- Blt1/gi complex (Complex from Homo sapiens)
- Water (18 Da, Ligand)
- Scfv16 (26 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- [(2r)-2-[(z)-hexadec-9-enoyl]oxy-3-[oxidanyl-[(2s,3r,5r,6s)-2,3,4,5,6-pentakis(oxidanyl)cyclohexyl]oxy-phosphoryl]oxy-propyl] octadecanoate (837 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Leukotriene b4 (336 Da, Ligand)
ghrelin-bound ghrelin receptor in complex with Gq
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7f9y
Q-score: 0.469
Wang Y, Guo S, Zhuang Y, Yun Y, Xu P, He X, Guo J, Yin W, Xu HE, Xie X, Jiang Y
Nat Commun (2021) 12 pp. 5064-5064 [ DOI: doi:10.1038/s41467-021-25364-2 Pubmed: 34417468 ]
- Octanoic acid (caprylic acid) (144 Da, Ligand)
- Soluble cytochrome b562 (74 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Ghrelin-bound ghrelin receptor in complex with gq (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (40 kDa, Protein from Homo sapiens)
- Engineered g-alpha-q subunit (41 kDa, Protein from Homo sapiens)
- Nb35 (15 kDa, Protein from Lama glama)
- Ghrelin-28 (3 kDa, Protein from Homo sapiens)