Cryo EM structure of a Na+-bound Na+,K+-ATPase in the E1 state
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7e1z
Q-score: 0.479
Guo Y, Zhang Y, Yan R, Huang B, Ye F, Wu L, Chi X, Shi Y, Zhou Q
Nat Commun (2022) 13 pp. 3957-3957 [ Pubmed: 35803952 DOI: doi:10.1038/s41467-022-31602-y ]
- Sodium/potassium-transporting atpase subunit beta-1 (35 kDa, Protein from Homo sapiens)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Water (18 Da, Ligand)
- Sodium/potassium-transporting atpase subunit gamma (7 kDa, Protein from Homo sapiens)
- Sodium/potassium-transporting atpase subunit alpha-1 (113 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Cryo em structure of a na+-bound na+,k+-atpase in the e1 state (Complex from Homo sapiens)
- Sodium ion (22 Da, Ligand)
Cryo EM structure of a K+-bound Na+,K+-ATPase in the E2 state
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 7e20
Q-score: 0.563
Guo Y, Zhang Y, Yan R, Huang B, Ye F, Wu L, Chi X, Shi Y, Zhou Q
Nat Commun (2022) 13 pp. 3957-3957 [ Pubmed: 35803952 DOI: doi:10.1038/s41467-022-31602-y ]
- Sodium/potassium-transporting atpase subunit beta-1 (35 kDa, Protein from Homo sapiens)
- Potassium ion (39 Da, Ligand)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Cryo em structure of a k+-bound na+,k+-atpase in the e2 state (Complex from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Water (18 Da, Ligand)
- Sodium/potassium-transporting atpase subunit gamma (7 kDa, Protein from Homo sapiens)
- Sodium/potassium-transporting atpase subunit alpha-1 (113 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Cholesterol hemisuccinate (486 Da, Ligand)
Cryo EM structure of a Na+-bound Na+,K+-ATPase in the E1 state with ATP-gamma-S
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7e21
Q-score: 0.535
Guo Y, Zhang Y, Yan R, Huang B, Ye F, Wu L, Chi X, Shi Y, Zhou Q
Nat Commun (2022) 13 pp. 3957-3957 [ Pubmed: 35803952 DOI: doi:10.1038/s41467-022-31602-y ]
- Sodium/potassium-transporting atpase subunit beta-1 (35 kDa, Protein from Homo sapiens)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Water (18 Da, Ligand)
- Sodium/potassium-transporting atpase subunit gamma (7 kDa, Protein from Homo sapiens)
- Cryo em structure of a na+-bound na+,k+-atpase in the e1 state with atp-gamma-s (Complex from Homo sapiens)
- Sodium/potassium-transporting atpase subunit alpha-1 (113 kDa, Protein from Homo sapiens)
- Phosphothiophosphoric acid-adenylate ester (523 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Sodium ion (22 Da, Ligand)