Cryo-EM structure of the Apo CCR1-Gi complex
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7vl8
Q-score: 0.454
Shao Z, Shen Q, Yao B, Mao C, Chen LN, Zhang H, Shen DD, Zhang C, Li W, Du X, Li F, Ma H, Chen ZH, Xu HE, Ying S, Zhang Y, Shen H
Nat Chem Biol (2022) 18 pp. 264-271 [ DOI: doi:10.1038/s41589-021-00918-z Pubmed: 34949837 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- C-c chemokine receptor type 1 (42 kDa, Protein from Homo sapiens)
- Scfv16 (27 kDa, Protein from Homo sapiens)
- Apo form ccr1-gi complex (Complex from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
Cryo-EM structure of the CCL15(26-92) bound CCR1-Gi complex
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 7vl9
Q-score: 0.563
Shao Z, Shen Q, Yao B, Mao C, Chen LN, Zhang H, Shen DD, Zhang C, Li W, Du X, Li F, Ma H, Chen ZH, Xu HE, Ying S, Zhang Y, Shen H
Nat Chem Biol (2022) 18 pp. 264-271 [ DOI: doi:10.1038/s41589-021-00918-z Pubmed: 34949837 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Ccl15(26-92) (8 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- C-c chemokine receptor type 1 (42 kDa, Protein from Homo sapiens)
- Scfv16 (27 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Ccl15(26-92)-bound ccr1-gi complex (Complex from Homo sapiens)
Cryo-EM structure of the CCL15(27-92) bound CCR1-Gi complex
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 7vla
Q-score: 0.561
Shao Z, Shen Q, Yao B, Mao C, Chen LN, Zhang H, Shen DD, Zhang C, Li W, Du X, Li F, Ma H, Chen ZH, Xu HE, Ying S, Zhang Y, Shen H
Nat Chem Biol (2022) 18 pp. 264-271 [ DOI: doi:10.1038/s41589-021-00918-z Pubmed: 34949837 ]
- Ccl15(27-92) (8 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- C-c chemokine receptor type 1 (42 kDa, Protein from Homo sapiens)
- Scfv16 (27 kDa, Protein from Homo sapiens)
- Ccl15(27-92)-bound ccr1-gi complex (Complex from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)