Cryo-EM structure of human CMKLR1-Gi complex bound to chemerin
Resolution: 3.18 Å
EM Method: Single-particle
Fitted PDBs: 8zjg
Q-score: 0.486
Commun Biol (2024) 7 pp. 1598-1598 [ DOI: doi:10.1038/s42003-024-07228-9 Pubmed: 39616240 ]
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- Retinoic acid receptor responder protein 2 chemerinv (15 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Scfv16 (26 kDa, Protein from Vicugna pacos)
- Human chemerin receptor 1-gi complex bound to chemerin (Complex from Homo sapiens)
- Chemerin-like receptor 1 (42 kDa, Protein from Homo sapiens)
Cryo-EM structure of human GPR1 bound to chemerin
To Be Published
- G-protein coupled receptor 1 (35 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Guanine nucleotide-binding protein subunit gamma (6 kDa, Protein from Homo sapiens)
- Retinoic acid receptor responder protein 2 (15 kDa, Protein from Homo sapiens)
- Human gpr1 in complex with chemerin and heterotrimeric gi proteins (Complex from Homo sapiens)
- Scfv16 (26 kDa, Protein from Vicugna pacos)
Resolution: 2.81 Å
EM Method: Single-particle
Fitted PDBs: 7ykd
Q-score: 0.549
Wang J, Chen G, Liao Q, Lyu W, Liu A, Zhu L, Du Y, Ye RD
PNAS (2023) 120 pp. e2214324120-e2214324120 [ Pubmed: 36881626 DOI: doi:10.1073/pnas.2214324120 ]
- Scfv16 (Complex)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Chemerin-like receptor 1, guanine nucleotide-binding protein g(i) subunit alpha-1,guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1,guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (Complex from Vicugna pacos)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Cmklr1-gi -scfv16 complex (150 kDa, Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Scfv16 (26 kDa, Protein from Vicugna pacos)
- Cholesterol (386 Da, Ligand)
- Retinoic acid receptor responder protein 2 (1 kDa, Protein from Homo sapiens)
- Retinoic acid receptor responder protein 2 (Complex from Homo sapiens)
- Chemerin-like receptor 1 (42 kDa, Protein from Homo sapiens)