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sample_name:"Carrier protein" AND film_detector_model:"FEI FALCON III (4K X 4K)"
human mitoribosomal large subunit assembly intermediate 1 with GTPBP10-GTPBP7
Release date: Dec. 13, 2023
Resolution: 3.03 Å
EM Method: Single-particle
Fitted PDBs: 8pk0
Q-score: 0.455
Resolution: 3.03 Å
EM Method: Single-particle
Fitted PDBs: 8pk0
Q-score: 0.455
Nat Commun (2023) 14 pp. 7991-7991 [ Pubmed: 38042949 DOI: doi:10.1038/s41467-023-43599-z ]
Sample:
- 39s ribosomal protein l4, mitochondrial (34 kDa, Protein from Homo sapiens)
- Growth arrest and dna damage-inducible proteins-interacting protein 1 (25 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l19, mitochondrial (33 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l21, mitochondrial (22 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l34, mitochondrial (10 kDa, Protein from Homo sapiens)
- Peptidyl-trna hydrolase ict1, mitochondrial (23 kDa, Protein from Homo sapiens)
- Acyl carrier protein, mitochondrial (17 kDa, Protein from Homo sapiens)
- Mief1 upstream open reading frame protein (8 kDa, Protein from Homo sapiens)
- 5-methylcytosine rrna methyltransferase nsun4 (43 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l2, mitochondrial (33 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l55, mitochondrial (15 kDa, Protein from Homo sapiens)
- Phosphoaminophosphonic acid-guanylate ester (522 Da, Ligand)
- 39s ribosomal protein l44, mitochondrial (37 kDa, Protein from Homo sapiens)
- Mitochondrial ribosome-associated gtpase 1 (37 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l42, mitochondrial (16 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l40, mitochondrial (24 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l10, mitochondrial (29 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l45, mitochondrial (35 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l54, mitochondrial (15 kDa, Protein from Homo sapiens)
- Ribosomal protein 63, mitochondrial (12 kDa, Protein from Homo sapiens)
- Potassium ion (39 Da, Ligand)
- 39s ribosomal protein l13, mitochondrial (20 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l20, mitochondrial (17 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l32, mitochondrial (21 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l48, mitochondrial (23 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l41, mitochondrial (15 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml43 (23 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l9, mitochondrial (30 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l28, mitochondrial (30 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l49, mitochondrial (19 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l16, mitochondrial (28 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l37, mitochondrial (48 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l35, mitochondrial (21 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l38, mitochondrial (44 kDa, Protein from Homo sapiens)
- 16s rrna + pre-h68-71 segment (509 kDa, RNA from Homo sapiens)
- 39s ribosomal protein s18a, mitochondrial (22 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l50, mitochondrial (18 kDa, Protein from Homo sapiens)
- S-(2-{[n-(2-hydroxy-4-{[hydroxy(oxido)phosphino]oxy}-3,3-dimethylbutanoyl)-beta-alanyl]amino}ethyl) decanethioate (496 Da, Ligand)
- 39s ribosomal protein l22, mitochondrial (23 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l52, mitochondrial (13 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l24, mitochondrial (24 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l15, mitochondrial (33 kDa, Protein from Homo sapiens)
- Transcription termination factor 4, mitochondrial (44 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l27, mitochondrial (16 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l51, mitochondrial (15 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l18, mitochondrial (20 kDa, Protein from Homo sapiens)
- Large mitoribosomal subunit biogenesis intermediate with gtpbp10, gtpbp7, nsun4-mterf4, acp-module (1 MDa, Complex from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- 39s ribosomal protein l33, mitochondrial (7 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l39, mitochondrial (38 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l30, mitochondrial (18 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l17, mitochondrial (20 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l3, mitochondrial (38 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- 39s ribosomal protein s30, mitochondrial (50 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l23, mitochondrial (17 kDa, Protein from Homo sapiens)
- Cp trna-val (22 kDa, RNA from Homo sapiens)
- 39s ribosomal protein l14, mitochondrial (15 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l11, mitochondrial (20 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l47, mitochondrial (29 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l53, mitochondrial (12 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l46, mitochondrial (31 kDa, Protein from Homo sapiens)
- Mitochondrial assembly of ribosomal large subunit protein 1 (26 kDa, Protein from Homo sapiens)
- S-adenosylmethionine (398 Da, Ligand)
- Gtp-binding protein 10 (42 kDa, Protein from Homo sapiens)
Mitochondrial complex I from Mus musculus in the active state bound with piericidin A
Release date: Aug. 9, 2023
Resolution: 2.84 Å
EM Method: Single-particle
Fitted PDBs: 8olt
Q-score: 0.628
Resolution: 2.84 Å
EM Method: Single-particle
Fitted PDBs: 8olt
Q-score: 0.628
Grba DN, Chung I, Bridges HR, Agip AA, Hirst J
Sci Adv (2023) 9 pp. eadi1359-eadi1359 [ Pubmed: 37531432 DOI: doi:10.1126/sciadv.adi1359 ]
Sample:
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (52 kDa, Protein from house mouse)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from house mouse)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from house mouse)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (21 kDa, Protein from house mouse)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (22 kDa, Protein from house mouse)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from house mouse)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from house mouse)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (42 kDa, Protein from house mouse)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (79 kDa, Protein from house mouse)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from house mouse)
- Cardiolipin (1 kDa, Ligand)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Piericidin a (415 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from house mouse)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from house mouse)
- Acyl carrier protein, mitochondrial (17 kDa, Protein from house mouse)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (10 kDa, Protein from house mouse)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from house mouse)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from house mouse)
- Nadh-ubiquinone oxidoreductase chain 1 (36 kDa, Protein from house mouse)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (24 kDa, Protein from house mouse)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from house mouse)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from house mouse)
- Water (18 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from house mouse)
- Nadh-ubiquinone oxidoreductase chain 2 (38 kDa, Protein from house mouse)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (15 kDa, Protein from house mouse)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (15 kDa, Protein from house mouse)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (17 kDa, Protein from house mouse)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from house mouse)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from house mouse)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (24 kDa, Protein from house mouse)
- Mitochondrial respiratory complex i (1 MDa, Complex from Mus musculus)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from house mouse)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from house mouse)
- Magnesium ion (24 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from house mouse)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from house mouse)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from house mouse)
- Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (8 kDa, Protein from house mouse)
- Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (11 kDa, Protein from house mouse)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Myristic acid (228 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from house mouse)
- Flavin mononucleotide (456 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (11 kDa, Protein from house mouse)
- Nadh-ubiquinone oxidoreductase chain 6 (18 kDa, Protein from house mouse)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from house mouse)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (13 kDa, Protein from house mouse)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7, methylglyoxal bis-(guanylhydrazone), nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from Mus musculus)
- Sodium ion (22 Da, Ligand)
- ~{s}-[2-[3-[[(2~{r})-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl] (3~{s})-3-oxidanyltetradecanethioate (584 Da, Ligand)
- Iron/sulfur cluster (351 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from house mouse)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from house mouse)
- Dodecyl-beta-d-maltoside (510 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from house mouse)
Complex I from Ovis aries, at pH7.4, Open state
Release date: Sept. 21, 2022
Resolution: 3.16 Å
EM Method: Single-particle
Fitted PDBs: 7zd6
Q-score: 0.561
Resolution: 3.16 Å
EM Method: Single-particle
Fitted PDBs: 7zd6
Q-score: 0.561
Kravchuk V, Petrova O, Kampjut D, Wojciechowska-Bason A, Breese Z, Sazanov L
Nature (2022) 609 pp. 808-814 [ DOI: doi:10.1038/s41586-022-05199-7 Pubmed: 36104567 ]
Sample:
- Complex i-pdsw (20 kDa, Protein from sheep)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (20 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (36 kDa, Protein from sheep)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (16 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (14 kDa, Protein from sheep)
- 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione (322 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (18 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (14 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (9 kDa, Protein from sheep)
- Nadh:ubiquinone oxidoreductase subunit b4 (14 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 4 (52 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (24 kDa, Protein from sheep)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Acyl carrier protein (17 kDa, Protein from sheep)
- Potassium ion (39 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (21 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (47 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (5 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (17 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (7 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (8 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (13 kDa, Protein from sheep)
- Complex i-49kd (52 kDa, Protein from sheep)
- Nadh:ubiquinone oxidoreductase subunit a9 (43 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (13 kDa, Protein from Ovis aries)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (5 kDa, Protein from sheep)
- Adenosine monophosphate (347 Da, Ligand)
- Mitochondrial complex i, b14.5a subunit (12 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (10 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from sheep)
- Complex i-mwfe (8 kDa, Protein from sheep)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Myristic acid (228 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (8 kDa, Protein from sheep)
- Flavin mononucleotide (456 Da, Ligand)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Complex i from ovis aries, at ph7.4, open state (1 MDa, Complex from Ovis aries)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from sheep)
- Iron/sulfur cluster (351 Da, Ligand)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (75 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (11 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (23 kDa, Protein from sheep)
- Mitochondrial complex i, b17 subunit (15 kDa, Protein from sheep)
Complex I from Ovis aries at pH7.4, Closed state
Release date: Sept. 21, 2022
Resolution: 3.46 Å
EM Method: Single-particle
Fitted PDBs: 7zdh
Q-score: 0.513
Resolution: 3.46 Å
EM Method: Single-particle
Fitted PDBs: 7zdh
Q-score: 0.513
Kravchuk V, Petrova O, Kampjut D, Wojciechowska-Bason A, Breese Z, Sazanov L
Nature (2022) 609 pp. 808-814 [ DOI: doi:10.1038/s41586-022-05199-7 Pubmed: 36104567 ]
Sample:
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (49 kDa, Protein from sheep)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from sheep)
- Nadh:ubiquinone oxidoreductase subunit a6 (13 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (36 kDa, Protein from sheep)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Nadh:ubiquinone oxidoreductase subunit a9 (38 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (16 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (14 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (18 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (14 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (9 kDa, Protein from sheep)
- Nadh:ubiquinone oxidoreductase subunit b4 (14 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 4 (52 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (24 kDa, Protein from sheep)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Acyl carrier protein (17 kDa, Protein from sheep)
- Potassium ion (39 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (21 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (47 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from sheep)
- Complex i-23kd (24 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (5 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (17 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (7 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (8 kDa, Protein from sheep)
- Mitochondrial complex i, b13 subunit (13 kDa, Protein from sheep)
- Complex i from ovis aries at ph7.4, closed state (1 MDa, Complex from Ovis aries)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (20 kDa, Protein from sheep)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (5 kDa, Protein from sheep)
- Adenosine monophosphate (347 Da, Ligand)
- Mitochondrial complex i, b14.5a subunit (12 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (10 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from sheep)
- Complex i-mwfe (8 kDa, Protein from sheep)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Myristic acid (228 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (8 kDa, Protein from sheep)
- Flavin mononucleotide (456 Da, Ligand)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from sheep)
- Iron/sulfur cluster (351 Da, Ligand)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (75 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (11 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (23 kDa, Protein from sheep)
- Mitochondrial complex i, b17 subunit (15 kDa, Protein from sheep)
Complex I from Ovis aries at pH5.5, Open state
Release date: Sept. 21, 2022
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 7zdj
Q-score: 0.547
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 7zdj
Q-score: 0.547
Kravchuk V, Petrova O, Kampjut D, Wojciechowska-Bason A, Breese Z, Sazanov L
Nature (2022) 609 pp. 808-814 [ DOI: doi:10.1038/s41586-022-05199-7 Pubmed: 36104567 ]
Sample:
- Complex i-pdsw (20 kDa, Protein from sheep)
- Complex i subunit b13 (13 kDa, Protein from sheep)
- Complex i-b14.7 (14 kDa, Protein from sheep)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Complex i-9kd (5 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (36 kDa, Protein from sheep)
- Complex i-b22 (21 kDa, Protein from sheep)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Complex i-aggg (7 kDa, Protein from sheep)
- Complex i-sgdh (16 kDa, Protein from sheep)
- Complex i-kfyi (5 kDa, Protein from sheep)
- Complex i-b12 (8 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (18 kDa, Protein from sheep)
- Complex i-b18 (14 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (14 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (9 kDa, Protein from sheep)
- Complex i-23kd (20 kDa, Protein from sheep)
- Nadh:ubiquinone oxidoreductase subunit b4 (14 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 4 (52 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from sheep)
- Complex i-b9 (8 kDa, Protein from sheep)
- Acyl carrier protein (17 kDa, Protein from sheep)
- Complex i-30kd (24 kDa, Protein from sheep)
- Potassium ion (39 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (47 kDa, Protein from sheep)
- Complex i from ovis aries at ph5.5, open state (1 MDa, Complex from Ovis aries)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from sheep)
- Complex i-49kd (52 kDa, Protein from sheep)
- Nadh:ubiquinone oxidoreductase subunit a9 (43 kDa, Protein from sheep)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Complex i-mnll (6 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (10 kDa, Protein from sheep)
- Mitochondrial complex i, b14.5a subunit (12 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from sheep)
- Complex i-mwfe (8 kDa, Protein from sheep)
- Complex i-20kd (17 kDa, Protein from sheep)
- Myristic acid (228 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from sheep)
- Flavin mononucleotide (456 Da, Ligand)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Complex i-b14 (13 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from sheep)
- Complex i-esss (11 kDa, Protein from sheep)
- Iron/sulfur cluster (351 Da, Ligand)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (75 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (23 kDa, Protein from sheep)
- Mitochondrial complex i, b17 subunit (15 kDa, Protein from sheep)
Complex I from Ovis aries at pH5.5, Closed state
Release date: Sept. 21, 2022
Resolution: 3.44 Å
EM Method: Single-particle
Fitted PDBs: 7zdm
Q-score: 0.524
Resolution: 3.44 Å
EM Method: Single-particle
Fitted PDBs: 7zdm
Q-score: 0.524
Kravchuk V, Petrova O, Kampjut D, Wojciechowska-Bason A, Breese Z, Sazanov L
Nature (2022) 609 pp. 808-814 [ DOI: doi:10.1038/s41586-022-05199-7 Pubmed: 36104567 ]
Sample:
- Complex i from ovis aries at ph5.5, closed state (1 MDa, Complex from Ovis aries)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Mitochondrial complex i, esss subunit (17 kDa, Protein from sheep)
- Nadh:ubiquinone oxidoreductase subunit a6 (16 kDa, Protein from sheep)
- Nadh:ubiquinone oxidoreductase subunit b4 (15 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 4 (52 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from sheep)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from sheep)
- Acyl carrier protein (17 kDa, Protein from sheep)
- Complex i-9kd (11 kDa, Protein from sheep)
- Potassium ion (39 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (20 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (12 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from sheep)
- Mitochondrial complex i, b13 subunit (13 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from sheep)
- Complex i-20kd (24 kDa, Protein from sheep)
- Complex i-23kd (24 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from sheep)
- Nadh:ubiquinone oxidoreductase subunit b9 (21 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from sheep)
- Nadh:ubiquinone oxidoreductase subunit a3 (9 kDa, Protein from sheep)
- Complex i-49kd (52 kDa, Protein from sheep)
- Nadh:ubiquinone oxidoreductase subunit a9 (43 kDa, Protein from sheep)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (11 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from sheep)
- Mitochondrial complex i, b14.5a subunit (12 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (8 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (7 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from sheep)
- Adenosine monophosphate (347 Da, Ligand)
- Complex i-mwfe (8 kDa, Protein from sheep)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Myristic acid (228 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from sheep)
- Nadh:ubiquinone oxidoreductase core subunit s3 (30 kDa, Protein from sheep)
- Flavin mononucleotide (456 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from sheep)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from sheep)
- Nadh:ubiquinone oxidoreductase core subunit s1 (79 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from sheep)
- Nadh:ubiquinone oxidoreductase subunit b7 (16 kDa, Protein from sheep)
- Iron/sulfur cluster (351 Da, Ligand)
- Mitochondrial complex i, 24 kda subunit (27 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from sheep)
- Mitochondrial complex i, b17 subunit (15 kDa, Protein from sheep)
Complex I from Ovis aries at pH9, Open state
Release date: Sept. 21, 2022
Resolution: 3.88 Å
EM Method: Single-particle
Fitted PDBs: 7zdp
Q-score: 0.437
Resolution: 3.88 Å
EM Method: Single-particle
Fitted PDBs: 7zdp
Q-score: 0.437
Kravchuk V, Petrova O, Kampjut D, Wojciechowska-Bason A, Breese Z, Sazanov L
Nature (2022) 609 pp. 808-814 [ DOI: doi:10.1038/s41586-022-05199-7 Pubmed: 36104567 ]
Sample:
- Complex i-pdsw (20 kDa, Protein from sheep)
- Complex i subunit b13 (13 kDa, Protein from sheep)
- Complex i-b14.7 (14 kDa, Protein from sheep)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Complex i-9kd (5 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (36 kDa, Protein from sheep)
- Complex i from ovis aries at ph9, open state (1 MDa, Complex from Ovis aries)
- Complex i-b22 (21 kDa, Protein from sheep)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Complex i-aggg (7 kDa, Protein from sheep)
- Complex i-sgdh (16 kDa, Protein from sheep)
- Complex i-kfyi (5 kDa, Protein from sheep)
- Complex i-b12 (8 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (18 kDa, Protein from sheep)
- Complex i-b18 (14 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (14 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (9 kDa, Protein from sheep)
- Complex i-23kd (20 kDa, Protein from sheep)
- Nadh:ubiquinone oxidoreductase subunit b4 (14 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 4 (52 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from sheep)
- Complex i-b9 (8 kDa, Protein from sheep)
- Acyl carrier protein (17 kDa, Protein from sheep)
- Complex i-30kd (24 kDa, Protein from sheep)
- Potassium ion (39 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (47 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from sheep)
- Complex i-49kd (52 kDa, Protein from sheep)
- Nadh:ubiquinone oxidoreductase subunit a9 (43 kDa, Protein from sheep)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Adenosine monophosphate (347 Da, Ligand)
- Complex i-mnll (6 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (10 kDa, Protein from sheep)
- Mitochondrial complex i, b14.5a subunit (12 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from sheep)
- Complex i-mwfe (8 kDa, Protein from sheep)
- Complex i-20kd (17 kDa, Protein from sheep)
- Myristic acid (228 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from sheep)
- Flavin mononucleotide (456 Da, Ligand)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Complex i-b14 (13 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from sheep)
- Complex i-esss (11 kDa, Protein from sheep)
- Iron/sulfur cluster (351 Da, Ligand)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (75 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (23 kDa, Protein from sheep)
- Mitochondrial complex i, b17 subunit (15 kDa, Protein from sheep)
Complex I from Ovis aries at pH9, Closed state
Release date: Sept. 21, 2022
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7zeb
Q-score: 0.452
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7zeb
Q-score: 0.452
Kravchuk V, Petrova O, Kampjut D, Wojciechowska-Bason A, Breese Z, Sazanov L
Nature (2022) 609 pp. 808-814 [ DOI: doi:10.1038/s41586-022-05199-7 Pubmed: 36104567 ]
Sample:
- Complex i-pdsw (20 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (49 kDa, Protein from sheep)
- Complex i-b14.7 (14 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (13 kDa, Protein from sheep)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Complex i-9kd (5 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (36 kDa, Protein from sheep)
- Complex i-b22 (21 kDa, Protein from sheep)
- Nadh:ubiquinone oxidoreductase subunit a9 (38 kDa, Protein from sheep)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Complex i-aggg (7 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (14 kDa, Protein from sheep)
- Complex i-sgdh (16 kDa, Protein from sheep)
- Complex i-kfyi (5 kDa, Protein from sheep)
- Complex i-b12 (8 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (18 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (14 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (9 kDa, Protein from sheep)
- Nadh:ubiquinone oxidoreductase subunit b4 (14 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 4 (52 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from sheep)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Complex i-b9 (8 kDa, Protein from sheep)
- Acyl carrier protein (17 kDa, Protein from sheep)
- Complex i-30kd (24 kDa, Protein from sheep)
- Potassium ion (39 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (17 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (47 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from sheep)
- Complex i-23kd (24 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from sheep)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Adenosine monophosphate (347 Da, Ligand)
- Complex i-mnll (6 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (10 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from sheep)
- Complex i-mwfe (8 kDa, Protein from sheep)
- Myristic acid (228 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from sheep)
- Flavin mononucleotide (456 Da, Ligand)
- Complex i-b14 (13 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from sheep)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Complex i-esss (11 kDa, Protein from sheep)
- Iron/sulfur cluster (351 Da, Ligand)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (75 kDa, Protein from sheep)
- Complex i from ovis aries at ph9, closed state (1 MDa, Complex from Ovis aries)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (23 kDa, Protein from sheep)
Cryo-EM structure of the human mtLSU assembly intermediate upon MRM2 depletion - class 4
Release date: May 18, 2022
Resolution: 2.89 Å
EM Method: Single-particle
Fitted PDBs: 7qh7
Q-score: 0.441
Resolution: 2.89 Å
EM Method: Single-particle
Fitted PDBs: 7qh7
Q-score: 0.441
Rebelo-Guiomar P, Pellegrino S, Dent KC, Sas-Chen A, Miller-Fleming L, Garone C, Van Haute L, Rogan JF, Dinan A, Firth AE, Andrews B, Whitworth AJ, Schwartz S, Warren AJ, Minczuk M
Nat Commun (2022) 13 pp. 929-929 [ Pubmed: 35177605 DOI: doi:10.1038/s41467-022-28503-5 ]
Sample:
- 39s ribosomal protein l3, mitochondrial (34 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l42, mitochondrial (9 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l43, mitochondrial (16 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l32, mitochondrial (12 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l48, mitochondrial (2 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l22, mitochondrial (19 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l33, mitochondrial (5 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l38, mitochondrial (34 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l14, mitochondrial (12 kDa, Protein from Homo sapiens)
- Acyl carrier protein, mitochondrial (9 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l9, mitochondrial (11 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l45, mitochondrial (19 kDa, Protein from Homo sapiens)
- Human mitochondrial ribosome large subunit (Complex from Homo sapiens)
- 39s ribosomal protein s18a, mitochondrial (16 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l39, mitochondrial (33 kDa, Protein from Homo sapiens)
- Growth arrest and dna damage-inducible proteins-interacting protein 1 (11 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l10, mitochondrial (3 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l41, mitochondrial (14 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l24, mitochondrial (5 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l50, mitochondrial (12 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l13, mitochondrial (20 kDa, Protein from Homo sapiens)
- Mitochondrial assembly of ribosomal large subunit protein 1 (13 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l19, mitochondrial (25 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- 39s ribosomal protein l36, mitochondrial (4 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l2, mitochondrial (23 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l35, mitochondrial (11 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l37, mitochondrial (45 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l47, mitochondrial (21 kDa, Protein from Homo sapiens)
- Mitochondrial trnaval (19 kDa, RNA from Homo sapiens)
- 16s ribosomal rna (403 kDa, RNA from Homo sapiens)
- 39s ribosomal protein l51, mitochondrial (11 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- 39s ribosomal protein l17, mitochondrial (17 kDa, Protein from Homo sapiens)
- Peptidyl-trna hydrolase ict1, mitochondrial (14 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l44, mitochondrial (32 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l4, mitochondrial (28 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Ribosomal protein 63, mitochondrial (9 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l27, mitochondrial (11 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l52, mitochondrial (9 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l49, mitochondrial (15 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l21, mitochondrial (17 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l28, mitochondrial (28 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l16, mitochondrial (23 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l20, mitochondrial (16 kDa, Protein from Homo sapiens)
- 39s ribosomal protein s30, mitochondrial (45 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l34, mitochondrial (5 kDa, Protein from Homo sapiens)
- Mief1 upstream open reading frame protein (8 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l18, mitochondrial (16 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l23, mitochondrial (14 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l15, mitochondrial (32 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l30, mitochondrial (13 kDa, Protein from Homo sapiens)
Middle assembly intermediate of the Trypanosoma brucei mitoribosomal small subunit
Release date: March 2, 2022
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7pua
Q-score: 0.436
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7pua
Q-score: 0.436
Lenarcic T, Niemann M, Ramrath DJF, Calderaro S, Flugel T, Saurer M, Leibundgut M, Boehringer D, Prange C, Horn EK, Schneider A, Ban N
PNAS (2022) 119 [ Pubmed: 35042777 DOI: doi:10.1073/pnas.2114710118 ]
Sample:
- Mt-saf29 (20 kDa, Protein from Trypanosoma brucei brucei)
- Mt-saf37 (37 kDa, Protein from Trypanosoma brucei brucei)
- Ms52 (84 kDa, Protein from Trypanosoma brucei brucei)
- Mt-saf27 (26 kDa, Protein from Trypanosoma brucei brucei)
- Ms55 (66 kDa, Protein from Trypanosoma brucei brucei)
- Phosphate ion (94 Da, Ligand)
- Unkc (783 Da, Protein from Trypanosoma brucei brucei)
- Mt-saf5 (86 kDa, Protein from Trypanosoma brucei brucei)
- Protein fyv4, mitochondrial (22 kDa, Protein from Trypanosoma brucei brucei)
- Unkg (23 kDa, Protein from Trypanosoma brucei brucei)
- Water (18 Da, Ligand)
- Unk8 (2 kDa, Protein from Trypanosoma brucei brucei)
- Bs18m (36 kDa, Protein from Trypanosoma brucei brucei)
- Ms58 (35 kDa, Protein from Trypanosoma brucei brucei)
- Ppr_long domain-containing protein (116 kDa, Protein from Trypanosoma brucei brucei)
- Unkd (1 kDa, Protein from Trypanosoma brucei brucei)
- Ms74 (8 kDa, Protein from Trypanosoma brucei brucei)
- Dihydroflavine-adenine dinucleotide (787 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Ms69 (21 kDa, Protein from Trypanosoma brucei brucei)
- 9s rrna (919 Da, RNA from Trypanosoma brucei brucei)
- Ms73 (11 kDa, Protein from Trypanosoma brucei brucei)
- Us3m (9 kDa, Protein from Trypanosoma brucei brucei)
- Unkf (3 kDa, Protein from Trypanosoma brucei brucei)
- Middle assembly intermediate of the trypanosoma brucei mitoribosomal small subunit (Complex from Trypanosoma brucei brucei)
- Ms35 (98 kDa, Protein from Trypanosoma brucei brucei)
- Ms26 (51 kDa, Protein from Trypanosoma brucei brucei)
- Ms22 (73 kDa, Protein from Trypanosoma brucei brucei)
- Ms51 (93 kDa, Protein from Trypanosoma brucei brucei)
- Dna photolyase, putative (95 kDa, Protein from Trypanosoma brucei brucei)
- Unkp (2 kDa, Protein from Trypanosoma brucei brucei)
- Lmwpc domain-containing protein (30 kDa, Protein from Trypanosoma brucei brucei)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Bs16m (22 kDa, Protein from Trypanosoma brucei brucei)
- Ms49 (137 kDa, Protein from Trypanosoma brucei brucei)
- Ms38 (28 kDa, Protein from Trypanosoma brucei brucei)
- Ms72 (19 kDa, Protein from Trypanosoma brucei brucei)
- S-(2-{[n-(2-hydroxy-4-{[hydroxy(oxido)phosphino]oxy}-3,3-dimethylbutanoyl)-beta-alanyl]amino}ethyl) decanethioate (496 Da, Ligand)
- Unk (698 Da, Protein from Trypanosoma brucei brucei)
- Ms57 (45 kDa, Protein from Trypanosoma brucei brucei)
- Ms50 (131 kDa, Protein from Trypanosoma brucei brucei)
- Mt-saf39 (89 kDa, Protein from Trypanosoma brucei brucei)
- 9s rrna (198 kDa, RNA from Trypanosoma brucei brucei)
- Ribosomal_s5_c domain-containing protein (50 kDa, Protein from Trypanosoma brucei brucei)
- Ms63 (31 kDa, Protein from Trypanosoma brucei brucei)
- Us12m (10 kDa, Protein from Trypanosoma brucei brucei)
- Mt-saf38 (69 kDa, Protein from Trypanosoma brucei brucei)
- Mt-saf7 (76 kDa, Protein from Trypanosoma brucei brucei)
- Ms54 (72 kDa, Protein from Trypanosoma brucei brucei)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Us15m (50 kDa, Protein from Trypanosoma brucei brucei)
- Mt-saf21 (39 kDa, Protein from Trypanosoma brucei brucei)
- Acyl carrier protein (16 kDa, Protein from Trypanosoma brucei brucei)
- Unkk (2 kDa, Protein from Trypanosoma brucei brucei)
- Translation initiation factor if-2, putative (87 kDa, Protein from Trypanosoma brucei brucei)
- Ms37 (24 kDa, Protein from Trypanosoma brucei brucei)
- Mt-saf3 (106 kDa, Protein from Trypanosoma brucei brucei)
- Ms62 (32 kDa, Protein from Trypanosoma brucei brucei)
- 30s ribosomal protein s8, putative (32 kDa, Protein from Trypanosoma brucei brucei)
- Us19m (28 kDa, Protein from Trypanosoma brucei brucei)
- Magnesium ion (24 Da, Ligand)
- Acyl transferase-like protein, putative (60 kDa, Protein from Trypanosoma brucei brucei)
- Ms53 (75 kDa, Protein from Trypanosoma brucei brucei)
- Mt-saf31 (17 kDa, Protein from Trypanosoma brucei brucei)
- Duf4379 domain-containing protein (16 kDa, Protein from Trypanosoma brucei brucei)
- Bs6m (18 kDa, Protein from Trypanosoma brucei brucei)
- Ubiquitin-like domain-containing protein (26 kDa, Protein from Trypanosoma brucei brucei)
- Ms70 (21 kDa, Protein from Trypanosoma brucei brucei)
- Ms65 (30 kDa, Protein from Trypanosoma brucei brucei)
- Unki (528 Da, Protein from Trypanosoma brucei brucei)
- Ms59 (35 kDa, Protein from Trypanosoma brucei brucei)
- Us9m (50 kDa, Protein from Trypanosoma brucei brucei)
- Lysm domain-containing protein (94 kDa, Protein from Trypanosoma brucei brucei)
- Mt-saf22 (39 kDa, Protein from Trypanosoma brucei brucei)
- Mt-saf23 (38 kDa, Protein from Trypanosoma brucei brucei)
- Bs21m (23 kDa, Protein from Trypanosoma brucei brucei)
- Ms71 (20 kDa, Protein from Trypanosoma brucei brucei)
- Ms34 (28 kDa, Protein from Trypanosoma brucei brucei)
- Ms23 (36 kDa, Protein from Trypanosoma brucei brucei)
- Rhodanese domain-containing protein (30 kDa, Protein from Trypanosoma brucei brucei)
- Us14m (19 kDa, Protein from Trypanosoma brucei brucei)
- 30s ribosomal protein s17, putative (35 kDa, Protein from Trypanosoma brucei brucei)
- Unka (869 Da, Protein from Trypanosoma brucei brucei)
- Mt-saf9 (69 kDa, Protein from Trypanosoma brucei brucei)
- Ms33 (21 kDa, Protein from Trypanosoma brucei brucei)
- Us11m (37 kDa, Protein from Trypanosoma brucei brucei)
- Unkg (1 kDa, Protein from Trypanosoma brucei brucei)
- Ms56 (47 kDa, Protein from Trypanosoma brucei brucei)
- Duf4460 domain-containing protein (76 kDa, Protein from Trypanosoma brucei brucei)
- Ms29 (57 kDa, Protein from Trypanosoma brucei brucei)