Cryo-EM structure of an activated Cholecystokinin A receptor (CCKAR)-Gi complex
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7ezh
Q-score: 0.42
Liu Q, Yang D, Zhuang Y, Croll TI, Cai X, Dai A, He X, Duan J, Yin W, Ye C, Zhou F, Wu B, Zhao Q, Xu HE, Wang MW, Jiang Y
Nat Chem Biol (2021) 17 pp. 1238-1244 [ DOI: doi:10.1038/s41589-021-00841-3 ]
- Scfv16 (26 kDa, Protein from synthetic construct)
- Cholecystokinin-8 (1 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Cryo-em structure of an activated cholecystokinin a receptor (cckar)-gi complex (Complex from Homo sapiens)
- Cholecystokinin receptor type a (47 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
Cryo-EM structure of an activated Cholecystokinin A receptor (CCKAR)-Gs complex
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7ezk
Q-score: 0.435
Liu Q, Yang D, Zhuang Y, Croll TI, Cai X, Dai A, He X, Duan J, Yin W, Ye C, Zhou F, Wu B, Zhao Q, Xu HE, Wang MW, Jiang Y
Nat Chem Biol (2021) 17 pp. 1238-1244 [ DOI: doi:10.1038/s41589-021-00841-3 ]
- Cholecystokinin-8 (1 kDa, Protein from Homo sapiens)
- Cryo-em structure of an activated cholecystokinin a receptor (cckar)-gs complex (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Cholecystokinin receptor type a (47 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- Chimera of guanine nucleotide-binding protein g(i) subunit alpha-1 and guanine nucleotide-binding protein g(s) subunit alpha isoforms short (41 kDa, Protein from Homo sapiens)
Cryo-EM structure of an activated Cholecystokinin A receptor (CCKAR)-Gq complex
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7ezm
Q-score: 0.486
Liu Q, Yang D, Zhuang Y, Croll TI, Cai X, Dai A, He X, Duan J, Yin W, Ye C, Zhou F, Wu B, Zhao Q, Xu HE, Wang MW, Jiang Y
Nat Chem Biol (2021) 17 pp. 1238-1244 [ DOI: doi:10.1038/s41589-021-00841-3 ]
- Scfv16 (26 kDa, Protein from synthetic construct)
- Cholecystokinin-8 (1 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Cryo-em structure of an activated cholecystokinin a receptor (cckar)-gq complex (Complex from Homo sapiens)
- Fusion protein of guanine nucleotide-binding protein g(i) subunit alpha-1 and guanine nucleotide-binding protein g(q) subunit alpha-q (41 kDa, Protein from Homo sapiens)
- Cholecystokinin receptor type a (47 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)