NuA4 Histone Acetyltransferase Complex (Composite)
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7zvw
Q-score: 0.309
Frechard A, Faux C, Hexnerova R, Crucifix C, Papai G, Smirnova E, McKeon C, Ping FLY, Helmlinger D, Schultz P, Ben-Shem A
Nat Struct Mol Biol (2023) 30 pp. 1337-1345 [ Pubmed: 37550452 DOI: doi:10.1038/s41594-023-01056-x ]
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Swr1-complex protein 4 (64 kDa, Protein from Komagataella phaffii GS115)
- Actin (53 kDa, Protein from Komagataella phaffii GS115)
- Magnesium ion (24 Da, Ligand)
- Nua4 histone acetyltransferase complex (Complex from Komagataella phaffii GS115)
- Transcription-associated protein (438 kDa, Protein from Komagataella phaffii GS115)
- Enhancer of polycomb-like protein (86 kDa, Protein from Komagataella phaffii GS115)
- Actin (41 kDa, Protein from Komagataella phaffii GS115)
- Chromatin modification-related protein eaf1 (118 kDa, Protein from Komagataella phaffii GS115)
The NuA4 histone acetyltransferase complex from S. cerevisiae
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7yfp
Q-score: 0.334
Ji L, Zhao L, Xu K, Gao H, Zhou Y, Kornberg RD, Zhang H
PNAS (2022) 119 pp. e2214313119-e2214313119 [ DOI: doi:10.1073/pnas.2214313119 Pubmed: 36417436 ]
- Arp4 isoform 1 (54 kDa, Protein from Saccharomyces cerevisiae)
- Swr1-complex protein 4 (55 kDa, Protein from Saccharomyces cerevisiae)
- Actin (41 kDa, Protein from Saccharomyces cerevisiae)
- Chromatin modification-related protein eaf1 (112 kDa, Protein from Saccharomyces cerevisiae)
- The nua4 histone acetyltransferase complex (Complex from Saccharomyces cerevisiae)
- Transcription-associated protein 1 (433 kDa, Protein from Saccharomyces cerevisiae)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Enhancer of polycomb-like protein 1 (96 kDa, Protein from Saccharomyces cerevisiae)
Core module of the NuA4 complex in S. cerevisiae
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7yfn
Q-score: 0.414
Ji L, Zhao L, Xu K, Gao H, Zhou Y, Kornberg RD, Zhang H
PNAS (2022) 119 pp. e2214313119-e2214313119 [ Pubmed: 36417436 DOI: doi:10.1073/pnas.2214313119 ]
- Transcription-associated protein 1 (433 kDa, Protein from Saccharomyces cerevisiae)
- Cryo-em structure of nua4 complex (Complex from Saccharomyces cerevisiae)
- Swr1-complex protein 4 (55 kDa, Protein from Saccharomyces cerevisiae)
- Arp4 isoform 1 (54 kDa, Protein from Saccharomyces cerevisiae)
- Actin (41 kDa, Protein from Saccharomyces cerevisiae)
- Enhancer of polycomb-like protein 1 (96 kDa, Protein from Saccharomyces cerevisiae)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Chromatin modification-related protein eaf1 (112 kDa, Protein from Saccharomyces cerevisiae)
Structure of the Yeast NuA4 Histone Acetyltransferase Complex
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8esc
Q-score: 0.438
Zukin SA, Marunde MR, Popova IK, Soczek KM, Nogales E, Patel AB
eLife (2022) 11 [ DOI: doi:10.7554/eLife.81400 Pubmed: 36263929 ]
- Transcription-associated protein 1 (433 kDa, Protein from Saccharomyces cerevisiae)
- Swr1-complex protein 4 (55 kDa, Protein from Saccharomyces cerevisiae)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Actin (41 kDa, Protein from Saccharomyces cerevisiae)
- Enhancer of polycomb-like protein 1 (96 kDa, Protein from Saccharomyces cerevisiae)
- Magnesium ion (24 Da, Ligand)
- Chromatin modification-related protein eaf1 (112 kDa, Protein from Saccharomyces cerevisiae)
- Nua4 (1 MDa, Complex from Saccharomyces cerevisiae)
- Actin-related protein 4 (54 kDa, Protein from Saccharomyces cerevisiae)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7vvy
Q-score: 0.384
Qu K, Chen K, Wang H, Li X, Chen Z
Nature (2022) 610 pp. 569-574 [ Pubmed: 36198799 DOI: doi:10.1038/s41586-022-05303-x ]
- Enhancer of polycomb-like protein 1 (96 kDa, Protein from Saccharomyces cerevisiae S288C)
- Transcription-associated protein 1 (433 kDa, Protein from Saccharomyces cerevisiae)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Actin-related protein 4 (54 kDa, Protein from Saccharomyces cerevisiae S288C)
- Swr1-complex protein 4 (55 kDa, Protein from Saccharomyces cerevisiae S288C)
- Tra1 module of nua4 (Complex from Saccharomyces cerevisiae)
- Chromatin modification-related protein eaf1 (133 kDa, Protein from Saccharomyces cerevisiae S288C)
- Actin (41 kDa, Protein from Saccharomyces cerevisiae S288C)
Resolution: 8.8 Å
EM Method: Single-particle
Fitted PDBs: 7vvz
Q-score: 0.108
Qu K, Chen K, Wang H, Li X, Chen Z
Nature (2022) 610 pp. 569-574 [ Pubmed: 36198799 DOI: doi:10.1038/s41586-022-05303-x ]
- Dna (207-mer) (64 kDa, DNA from Saccharomyces cerevisiae)
- Actin-related protein 4 (54 kDa, Protein from Saccharomyces cerevisiae S288C)
- Histone h4 (11 kDa, Protein from Xenopus laevis)
- Actin (41 kDa, Protein from Saccharomyces cerevisiae S288C)
- Nua4 bound to the nucleosome (Complex from Saccharomyces cerevisiae)
- Chromatin modification-related protein yng2 (32 kDa, Protein from Saccharomyces cerevisiae S288C)
- Transcription-associated protein 1 (433 kDa, Protein from Saccharomyces cerevisiae)
- Chromatin modification-related protein eaf1 (133 kDa, Protein from Saccharomyces cerevisiae S288C)
- Epl1 arginine anchor (1 kDa, Protein from Saccharomyces cerevisiae)
- Chromatin modification-related protein eaf6 (12 kDa, Protein from Saccharomyces cerevisiae S288C)
- Histone h2a (14 kDa, Protein from Xenopus laevis)
- Histone h2b 1.1 (13 kDa, Protein from Xenopus laevis)
- Histone acetyltransferase esa1 (52 kDa, Protein from Saccharomyces cerevisiae S288C)
- Swr1-complex protein 4 (55 kDa, Protein from Saccharomyces cerevisiae S288C)
- Carboxymethyl coenzyme *a (825 Da, Ligand)
- Histone h3 (15 kDa, Protein from Xenopus laevis)
- Enhancer of polycomb-like protein 1 (96 kDa, Protein from Saccharomyces cerevisiae S288C)
- Dna (207-mer) (63 kDa, DNA from Saccharomyces cerevisiae)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
Resolution: 4.7 Å
EM Method: Single-particle
Fitted PDBs: 5y81
Q-score: 0.308
Wang X, Ahmad S, Zhang Z, Cote J, Cai G
Nat Commun (2018) 9 pp. 1147-1147 [ DOI: doi:10.1038/s41467-018-03504-5 Pubmed: 29559617 ]
- Actin-related protein 4 (54 kDa, Protein from Saccharomyces cerevisiae S288c)
- Eaf1-disorder domain (42 kDa, Protein from Saccharomyces cerevisiae)
- Transcription-associated protein 1 (303 kDa, Protein from Saccharomyces cerevisiae S288c)
- Nua4 teeaa sub-complex (Complex from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Chromatin modification-related protein eaf5 (31 kDa, Protein from Saccharomyces cerevisiae S288c)
- Chromatin modification-related protein eaf1 (39 kDa, Protein from Saccharomyces cerevisiae S288c)
- Transcription-associated protein 1 (130 kDa, Protein from Saccharomyces cerevisiae S288c)
- Actin (41 kDa, Protein from Saccharomyces cerevisiae S288c)
- Chromatin modification-related protein eaf1 (4 kDa, Protein from Saccharomyces cerevisiae S288c)