Cryo-EM structure of 227 Fab in complex with (NPNA)8 peptide
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8dyt
Q-score: 0.55
Martin GM, Torres JL, Pholcharee T, Oyen D, Flores-Garcia Y, Gibson G, Moskovitz R, Beutler N, Jung DD, Copps J, Lee WH, Gonzalez-Paez G, Emerling D, MacGill RS, Locke E, King CR, Zavala F, Wilson IA, Ward AB
Nat Commun (2023) 14 pp. 4546-4546 [ DOI: doi:10.1038/s41467-023-40151-x Pubmed: 37507365 ]
- 227 fab light chain, 227 fab heavy chain (Complex from Homo sapiens)
- Circumsporozoite protein (3 kDa, Protein from Plasmodium falciparum 3D7)
- 227 fab light chain (22 kDa, Protein from Homo sapiens)
- 227 fab heavy chain (49 kDa, Protein from Homo sapiens)
- 227 fab - (npna)8 complex (Complex)
- Circumsporozoite protein (Complex from Plasmodium falciparum)
Resolution: 3.72 Å
EM Method: Single-particle
Fitted PDBs: 8dyw
Q-score: 0.424
Martin GM, Torres JL, Pholcharee T, Oyen D, Flores-Garcia Y, Gibson G, Moskovitz R, Beutler N, Jung DD, Copps J, Lee WH, Gonzalez-Paez G, Emerling D, MacGill RS, Locke E, King CR, Zavala F, Wilson IA, Ward AB
Nat Commun (2023) 14 pp. 4546-4546 [ DOI: doi:10.1038/s41467-023-40151-x Pubmed: 37507365 ]
- 239 fab light chain (23 kDa, Protein from Homo sapiens)
- 239 fab heavy chain (49 kDa, Protein from Homo sapiens)
- 239 fab light chain, 239 fab heavy chain (Complex from Homo sapiens)
- Circumsporozoite protein (30 kDa, Protein from Plasmodium falciparum)
- 239 fab - rscsp complex (Complex)
- Circumsporozoite protein (Complex from Plasmodium falciparum)
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8dyx
Q-score: 0.514
Martin GM, Torres JL, Pholcharee T, Oyen D, Flores-Garcia Y, Gibson G, Moskovitz R, Beutler N, Jung DD, Copps J, Lee WH, Gonzalez-Paez G, Emerling D, MacGill RS, Locke E, King CR, Zavala F, Wilson IA, Ward AB
Nat Commun (2023) 14 pp. 4546-4546 [ DOI: doi:10.1038/s41467-023-40151-x Pubmed: 37507365 ]
- 311 heavy chain, 311 light chain (Complex from Homo sapiens)
- 311 fab - rscsp complex (Complex)
- 311 heavy chain (24 kDa, Protein from Homo sapiens)
- 311 light chain (22 kDa, Protein from Homo sapiens)
- Circumsporozoite protein (30 kDa, Protein from Plasmodium falciparum)
- Circumsporozoite protein (Complex from Plasmodium falciparum)
Resolution: 3.62 Å
EM Method: Single-particle
Fitted PDBs: 8dyy
Q-score: 0.505
Martin GM, Torres JL, Pholcharee T, Oyen D, Flores-Garcia Y, Gibson G, Moskovitz R, Beutler N, Jung DD, Copps J, Lee WH, Gonzalez-Paez G, Emerling D, MacGill RS, Locke E, King CR, Zavala F, Wilson IA, Ward AB
Nat Commun (2023) 14 pp. 4546-4546 [ DOI: doi:10.1038/s41467-023-40151-x Pubmed: 37507365 ]
- 334 fab light chain (23 kDa, Protein from Homo sapiens)
- 334 fab heavy chain, 334 fab light chain (Complex from Homo sapiens)
- 334 fab heavy chain (24 kDa, Protein from Homo sapiens)
- Circumsporozoite protein (30 kDa, Protein from Plasmodium falciparum)
- Circumsporozoite protein (Complex from Plasmodium falciparum)
- 334 fab - rscsp complex (Complex)
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 8dz3
Q-score: 0.579
Martin GM, Torres JL, Pholcharee T, Oyen D, Flores-Garcia Y, Gibson G, Moskovitz R, Beutler N, Jung DD, Copps J, Lee WH, Gonzalez-Paez G, Emerling D, MacGill RS, Locke E, King CR, Zavala F, Wilson IA, Ward AB
Nat Commun (2023) 14 pp. 4546-4546 [ DOI: doi:10.1038/s41467-023-40151-x Pubmed: 37507365 ]
- Circumsporozoite protein (Complex from Escherichia coli)
- 337 fab light chain (23 kDa, Protein from Homo sapiens)
- 337 fab heavy chain, 337 fab light chain (Complex from Homo sapiens)
- 337 fab heavy chain (24 kDa, Protein from Homo sapiens)
- 337 fab - rscsp complex (Complex)
- Circumsporozoite protein (30 kDa, Protein from Plasmodium falciparum)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8dz4
Q-score: 0.523
Martin GM, Torres JL, Pholcharee T, Oyen D, Flores-Garcia Y, Gibson G, Moskovitz R, Beutler N, Jung DD, Copps J, Lee WH, Gonzalez-Paez G, Emerling D, MacGill RS, Locke E, King CR, Zavala F, Wilson IA, Ward AB
Nat Commun (2023) 14 pp. 4546-4546 [ DOI: doi:10.1038/s41467-023-40151-x Pubmed: 37507365 ]
- 356 fab heavy chain (24 kDa, Protein from Homo sapiens)
- 356 fab light chain (23 kDa, Protein from Homo sapiens)
- 356 fab - rscsp complex (Complex)
- Circumsporozoite protein (30 kDa, Protein from Plasmodium falciparum)
- 356 fab light chain, 356 fab heavy chain (Complex from Homo sapiens)
- Circumsporozoite protein (Complex from Plasmodium falciparum)
Resolution: 3.84 Å
EM Method: Single-particle
Fitted PDBs: 8dz5
Q-score: 0.45
Martin GM, Torres JL, Pholcharee T, Oyen D, Flores-Garcia Y, Gibson G, Moskovitz R, Beutler N, Jung DD, Copps J, Lee WH, Gonzalez-Paez G, Emerling D, MacGill RS, Locke E, King CR, Zavala F, Wilson IA, Ward AB
Nat Commun (2023) 14 pp. 4546-4546 [ DOI: doi:10.1038/s41467-023-40151-x Pubmed: 37507365 ]
- 364 fab light chain (23 kDa, Protein from Homo sapiens)
- 364 fab - rscsp complex (Complex)
- 364 fab heavy chain (23 kDa, Protein from Homo sapiens)
- 364 fab heavy chain, 364 fab light chain (Complex from Homo sapiens)
- Circumsporozoite protein (30 kDa, Protein from Plasmodium falciparum)
- Circumsporozoite protein (Complex from Plasmodium falciparum)
Cryo-EM structure of L9 Fab in complex with rsCSP
Resolution: 3.36 Å
EM Method: Single-particle
Fitted PDBs: 8eh5
Q-score: 0.442
Martin GM, Fernandez-Quintero ML, Lee WH, Pholcharee T, Eshun-Wilson L, Liedl KR, Pancera M, Seder RA, Wilson IA, Ward AB
Nat Commun (2023) 14 pp. 2815-2815 [ DOI: doi:10.1038/s41467-023-38509-2 Pubmed: 37198165 ]
- Circumsporozoite protein (Complex from Plasmodium falciparum)
- L9 light chain (23 kDa, Protein from Homo sapiens)
- Trimeric complex of l9 fab with rscsp (Complex)
- L9 heavy chain, l9 light chain (Complex from Homo sapiens)
- L9 heavy chain (24 kDa, Protein from Homo sapiens)
- Circumsporozoite protein (30 kDa, Protein from Plasmodium falciparum)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8ek1
Q-score: 0.473
Tripathi P, Bender MF, Lei H, Da Silva Pereira L, Shen CH, Bonilla B, Dillon M, Ou L, Pancera M, Wang LT, Zhang B, Batista FD, Idris AH, Seder RA, Kwong PD
Structure (2023) 31 pp. 480-491.e4 [ DOI: doi:10.1016/j.str.2023.02.009 Pubmed: 36931276 ]
- L9 fab light chain (23 kDa, Protein from Homo sapiens)
- L9 fab heavy chain (24 kDa, Protein from Homo sapiens)
- Circumsporozoite protein (37 kDa, Protein from Plasmodium falciparum 3D7)
- Pfcsp in complex with antibody l9 (Complex from Homo sapiens)
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8eka
Q-score: 0.486
Tripathi P, Bender MF, Lei H, Da Silva Pereira L, Shen CH, Bonilla B, Dillon M, Ou L, Pancera M, Wang LT, Zhang B, Batista FD, Idris AH, Seder RA, Kwong PD
Structure (2023) 31 pp. 480-491.e4 [ DOI: doi:10.1016/j.str.2023.02.009 Pubmed: 36931276 ]
- Circumsporozoite protein (37 kDa, Protein from Plasmodium falciparum 3D7)
- L9 fab heavy chain (24 kDa, Protein from Homo sapiens)
- L9 fab light chain (23 kDa, Protein from Homo sapiens)
- Pfcsp in complex with antibody l9 (Complex from Homo sapiens)