Structures of the CRISPR-Cmr complex reveal mode of RNA target positioning
Taylor DW, Zhu Y, Staals RH, Kornfeld JE, Shinkai A, van der Oost J, Nogales E, Doudna JA
Science (2015) 348 pp. 581-585 [ DOI: doi:10.1126/science.aaa4535 Pubmed: 25837515 ]
- Apo crispr-cmr complex (365 kDa, Sample)
- Crispr-associated protein cmr3 (39 kDa, Protein from Thermus thermophilus)
- Crispr-associated protein crm2 (65 kDa, Protein from Thermus thermophilus)
- Crispr system cmr subunit cmr5 (12 kDa, Protein from Thermus thermophilus)
- Crispr rna (RNA from Thermus thermophilus)
- Crispr-associated protein tm1795 (44 kDa, Protein from Thermus thermophilus)
- Crispr-associated ramp cmr4 (37 kDa, Protein from Thermus thermophilus)
- Crispr-associated protein tm1791 (38 kDa, Protein from Thermus thermophilus)
Structures of the CRISPR-Cmr complex reveal mode of RNA target positioning
Taylor DW, Zhu Y, Staals RH, Kornfeld JE, Shinkai A, van der Oost J, Nogales E, Doudna JA
Science (2015) 348 pp. 581-585 [ DOI: doi:10.1126/science.aaa4535 Pubmed: 25837515 ]
- Crispr-associated protein cmr3 (39 kDa, Protein from Thermus thermophilus)
- Crispr-associated protein crm2 (65 kDa, Protein from Thermus thermophilus)
- Crispr system cmr subunit cmr5 (12 kDa, Protein from Thermus thermophilus)
- Smaller apo crispr-cmr complex (316 kDa, Sample)
- Crispr rna (RNA from Thermus thermophilus)
- Crispr-associated protein tm1795 (44 kDa, Protein from Thermus thermophilus)
- Crispr-associated ramp cmr4 (37 kDa, Protein from Thermus thermophilus)
- Crispr-associated protein tm1791 (38 kDa, Protein from Thermus thermophilus)
Structures of the CRISPR-Cmr complex reveal mode of RNA target positioning
Taylor DW, Zhu Y, Staals RH, Kornfeld JE, Shinkai A, van der Oost J, Nogales E, Doudna JA
Science (2015) 348 pp. 581-585 [ DOI: doi:10.1126/science.aaa4535 Pubmed: 25837515 ]
- Crispr-associated protein cmr3 (39 kDa, Protein from Thermus thermophilus)
- Crispr-associated protein crm2 (65 kDa, Protein from Thermus thermophilus)
- Target rna (16 kDa, RNA from Thermus thermophilus)
- Crispr system cmr subunit cmr5 (12 kDa, Protein from Thermus thermophilus)
- Crispr rna (RNA from Thermus thermophilus)
- Crispr-associated protein tm1795 (44 kDa, Protein from Thermus thermophilus)
- Crispr-associated ramp cmr4 (37 kDa, Protein from Thermus thermophilus)
- Crispr-associated protein tm1791 (38 kDa, Protein from Thermus thermophilus)
- Target-bound crispr-cmr complex (381 kDa, Sample)
Ramia NF, Spilman M, Tang L, Shao Y, Elmore J, Hale C, Cocozaki A, Bhattacharya N, Terns RM, Terns MP, Li H, Stagg SM
Cell Rep (2014) 9 pp. 1610-1617 [ Pubmed: 25482566 DOI: doi:10.1016/j.celrep.2014.11.007 ]
- Cmr1 (Protein from Pyrococcus furiosus)
- Cmr4 (Protein from Pyrococcus furiosus)
- Crrna (RNA from Pyrococcus furiosus)
- Cmr5 (Protein from Pyrococcus furiosus)
- Cmr3 (Protein from Pyrococcus furiosus)
- Target rna (RNA from unidentified)
- Cmr2 (Protein from Pyrococcus furiosus)
- Cmr6 (Protein from Pyrococcus furiosus)
- Cmr complex with crrna and target rna (Sample)
Ramia NF, Spilman M, Tang L, Shao Y, Elmore J, Hale C, Cocozaki A, Bhattacharya N, Terns RM, Terns MP, Li H, Stagg SM
Cell Rep (2014) 9 pp. 1610-1617 [ Pubmed: 25482566 DOI: doi:10.1016/j.celrep.2014.11.007 ]
- Cmr1 (Protein from Pyrococcus furiosus)
- Cmr4 (Protein from Pyrococcus furiosus)
- Crrna (RNA from Pyrococcus furiosus)
- Cmr5 (Protein from Pyrococcus furiosus)
- Cmr3 (Protein from Pyrococcus furiosus)
- Target rna (RNA from unidentified)
- Cmr1-6 with crrna and target rna (Sample)
- Cmr6 (Protein from Pyrococcus furiosus)
- Cmr2 (Protein from Pyrococcus furiosus)
Ramia NF, Spilman M, Tang L, Shao Y, Elmore J, Hale C, Cocozaki A, Bhattacharya N, Terns RM, Terns MP, Li H, Stagg SM
Cell Rep (2014) 9 pp. 1610-1617 [ Pubmed: 25482566 DOI: doi:10.1016/j.celrep.2014.11.007 ]
- Cmr4 (Protein from Pyrococcus furiosus)
- Filament of cmr4 and cmr5 (Sample)
- Cmr5 (Protein from Pyrococcus furiosus)
Electron microscopy of the negatively-stained Cmr complex from Thermus thermophilus HB8.
Staals RH, Agari Y, Maki-Yonekura S, Zhu Y, Taylor DW, van Duijn E, Barendregt A, Vlot M, Koehorst JJ, Sakamoto K, Masuda A, Dohmae N, Schaap PJ, Doudna JA, Heck AJ, Yonekura K, van der Oost J, Shinkai A
Mol Cell (2013) 52 pp. 135-145 [ DOI: doi:10.1016/j.molcel.2013.09.013 Pubmed: 24119403 ]
- Cmr1 (40 kDa, Protein from Thermus thermophilus)
- Cmr2 (65 kDa, Protein from Thermus thermophilus)
- Cmr4 (30 kDa, Protein from Thermus thermophilus)
- Cmr3 (40 kDa, Protein from Thermus thermophilus)
- Cmr5 (10 kDa, Protein from Thermus thermophilus)
- Cmr6 (40 kDa, Protein from Thermus thermophilus)
- Cmr complex from thermus thermophilus (400 kDa, Sample)
- Crrna (20 kDa, RNA from Thermus thermophilus)
Structure of an RNA silencing complex of the CRISPR-Cas immune system
Spilman M, Cocozaki A, Hale C, Shao Y, Ramia N, Terns R, Terns M, Li H, Stagg S
Mol Cell (2013) 52 pp. 146-152 [ Pubmed: 24119404 DOI: doi:10.1016/j.molcel.2013.09.008 ]
- Cmr4 (Protein from Pyrococcus furiosus)
- Cmr5 (Protein from Pyrococcus furiosus)
- Cmr4-cmr5 filament (520 kDa, Sample)
Structure of an RNA silencing complex of the CRISPR-Cas immune system
Spilman M, Cocozaki A, Hale C, Shao Y, Ramia N, Terns R, Terns M, Li H, Stagg S
Mol Cell (2013) 52 pp. 146-152 [ DOI: doi:10.1016/j.molcel.2013.09.008 Pubmed: 24119404 ]
- Cmr1 (Protein from Pyrococcus furiosus)
- Cmr5 (Protein from Pyrococcus furiosus)
- Cmr3 (Protein from Pyrococcus furiosus)
- Cmr1-6 effector complex (350 kDa, Sample)
- Cmr6 (Protein from Pyrococcus furiosus)
- Cmr4 (Protein from Pyrococcus furiosus)
- Cmr2 (Protein from Pyrococcus furiosus)
Structure and activity of an RNA-targeting Type III-B CRISPER-Cas complex
Staals RH, Agari Y, Maki-Yonekura S, Zhu Y, Taylor DW, van Duijn E, Barendregt A, Vlot M, Koehorst JJ, Sakamoto K, Masuda A, Dohmae N, Schaap PJ, Doudna JA, Heck AJ, Yonekura K, van der Oost J, Shinkai A
Mol Cell (2013) 52 pp. 135-145 [ DOI: doi:10.1016/j.molcel.2013.09.013 Pubmed: 24119403 ]
- Type iii-b crispr-cas complex of thermus thermophilus (365 kDa, Sample)
- Crispr-associated protein cmr3 (39 kDa, Protein from Thermus thermophilus)
- Crispr-associated protein crm2 (65 kDa, Protein from Thermus thermophilus)
- Crispr system cmr subunit cmr5 (12 kDa, Protein from Thermus thermophilus)
- Crispr rna (RNA from Thermus thermophilus)
- Crispr-associated protein tm1795 (44 kDa, Protein from Thermus thermophilus)
- Crispr-associated ramp cmr4 (37 kDa, Protein from Thermus thermophilus)
- Crispr-associated protein tm1791 (38 kDa, Protein from Thermus thermophilus)