Complex I from Ovis aries at pH5.5, Open state
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 7zdj
Q-score: 0.547
Kravchuk V, Petrova O, Kampjut D, Wojciechowska-Bason A, Breese Z, Sazanov L
Nature (2022) 609 pp. 808-814 [ DOI: doi:10.1038/s41586-022-05199-7 Pubmed: 36104567 ]
- Complex i-pdsw (20 kDa, Protein from sheep)
- Complex i subunit b13 (13 kDa, Protein from sheep)
- Complex i-b14.7 (14 kDa, Protein from sheep)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Complex i-9kd (5 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (36 kDa, Protein from sheep)
- Complex i-b22 (21 kDa, Protein from sheep)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Complex i-aggg (7 kDa, Protein from sheep)
- Complex i-sgdh (16 kDa, Protein from sheep)
- Complex i-kfyi (5 kDa, Protein from sheep)
- Complex i-b12 (8 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (18 kDa, Protein from sheep)
- Complex i-b18 (14 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (14 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (9 kDa, Protein from sheep)
- Complex i-23kd (20 kDa, Protein from sheep)
- Nadh:ubiquinone oxidoreductase subunit b4 (14 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 4 (52 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from sheep)
- Complex i-b9 (8 kDa, Protein from sheep)
- Acyl carrier protein (17 kDa, Protein from sheep)
- Complex i-30kd (24 kDa, Protein from sheep)
- Potassium ion (39 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (47 kDa, Protein from sheep)
- Complex i from ovis aries at ph5.5, open state (1 MDa, Complex from Ovis aries)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from sheep)
- Complex i-49kd (52 kDa, Protein from sheep)
- Nadh:ubiquinone oxidoreductase subunit a9 (43 kDa, Protein from sheep)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Complex i-mnll (6 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (10 kDa, Protein from sheep)
- Mitochondrial complex i, b14.5a subunit (12 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from sheep)
- Complex i-mwfe (8 kDa, Protein from sheep)
- Complex i-20kd (17 kDa, Protein from sheep)
- Myristic acid (228 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from sheep)
- Flavin mononucleotide (456 Da, Ligand)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Complex i-b14 (13 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from sheep)
- Complex i-esss (11 kDa, Protein from sheep)
- Iron/sulfur cluster (351 Da, Ligand)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (75 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (23 kDa, Protein from sheep)
- Mitochondrial complex i, b17 subunit (15 kDa, Protein from sheep)
Complex I from Ovis aries at pH9, Open state
Resolution: 3.88 Å
EM Method: Single-particle
Fitted PDBs: 7zdp
Q-score: 0.437
Kravchuk V, Petrova O, Kampjut D, Wojciechowska-Bason A, Breese Z, Sazanov L
Nature (2022) 609 pp. 808-814 [ DOI: doi:10.1038/s41586-022-05199-7 Pubmed: 36104567 ]
- Complex i-pdsw (20 kDa, Protein from sheep)
- Complex i subunit b13 (13 kDa, Protein from sheep)
- Complex i-b14.7 (14 kDa, Protein from sheep)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Complex i-9kd (5 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (36 kDa, Protein from sheep)
- Complex i from ovis aries at ph9, open state (1 MDa, Complex from Ovis aries)
- Complex i-b22 (21 kDa, Protein from sheep)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Complex i-aggg (7 kDa, Protein from sheep)
- Complex i-sgdh (16 kDa, Protein from sheep)
- Complex i-kfyi (5 kDa, Protein from sheep)
- Complex i-b12 (8 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (18 kDa, Protein from sheep)
- Complex i-b18 (14 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (14 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (9 kDa, Protein from sheep)
- Complex i-23kd (20 kDa, Protein from sheep)
- Nadh:ubiquinone oxidoreductase subunit b4 (14 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 4 (52 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from sheep)
- Complex i-b9 (8 kDa, Protein from sheep)
- Acyl carrier protein (17 kDa, Protein from sheep)
- Complex i-30kd (24 kDa, Protein from sheep)
- Potassium ion (39 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (47 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from sheep)
- Complex i-49kd (52 kDa, Protein from sheep)
- Nadh:ubiquinone oxidoreductase subunit a9 (43 kDa, Protein from sheep)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Adenosine monophosphate (347 Da, Ligand)
- Complex i-mnll (6 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (10 kDa, Protein from sheep)
- Mitochondrial complex i, b14.5a subunit (12 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from sheep)
- Complex i-mwfe (8 kDa, Protein from sheep)
- Complex i-20kd (17 kDa, Protein from sheep)
- Myristic acid (228 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from sheep)
- Flavin mononucleotide (456 Da, Ligand)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Complex i-b14 (13 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from sheep)
- Complex i-esss (11 kDa, Protein from sheep)
- Iron/sulfur cluster (351 Da, Ligand)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (75 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (23 kDa, Protein from sheep)
- Mitochondrial complex i, b17 subunit (15 kDa, Protein from sheep)
Complex I from Ovis aries at pH9, Closed state
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7zeb
Q-score: 0.452
Kravchuk V, Petrova O, Kampjut D, Wojciechowska-Bason A, Breese Z, Sazanov L
Nature (2022) 609 pp. 808-814 [ DOI: doi:10.1038/s41586-022-05199-7 Pubmed: 36104567 ]
- Complex i-pdsw (20 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (49 kDa, Protein from sheep)
- Complex i-b14.7 (14 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (13 kDa, Protein from sheep)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Complex i-9kd (5 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (36 kDa, Protein from sheep)
- Complex i-b22 (21 kDa, Protein from sheep)
- Nadh:ubiquinone oxidoreductase subunit a9 (38 kDa, Protein from sheep)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Complex i-aggg (7 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (14 kDa, Protein from sheep)
- Complex i-sgdh (16 kDa, Protein from sheep)
- Complex i-kfyi (5 kDa, Protein from sheep)
- Complex i-b12 (8 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (18 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (14 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (9 kDa, Protein from sheep)
- Nadh:ubiquinone oxidoreductase subunit b4 (14 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 4 (52 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from sheep)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Complex i-b9 (8 kDa, Protein from sheep)
- Acyl carrier protein (17 kDa, Protein from sheep)
- Complex i-30kd (24 kDa, Protein from sheep)
- Potassium ion (39 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (17 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (47 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from sheep)
- Complex i-23kd (24 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from sheep)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Adenosine monophosphate (347 Da, Ligand)
- Complex i-mnll (6 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (10 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from sheep)
- Complex i-mwfe (8 kDa, Protein from sheep)
- Myristic acid (228 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from sheep)
- Flavin mononucleotide (456 Da, Ligand)
- Complex i-b14 (13 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from sheep)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Complex i-esss (11 kDa, Protein from sheep)
- Iron/sulfur cluster (351 Da, Ligand)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (75 kDa, Protein from sheep)
- Complex i from ovis aries at ph9, closed state (1 MDa, Complex from Ovis aries)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (23 kDa, Protein from sheep)
A 3.7-angstrom structure of Yarrowia lipolytica complex I with an R121M mutation in NUCM.
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7b0n
Q-score: 0.467
Hameedi MA, Grba DN, Richardson KH, Jones AJY, Song W, Roessler MM, Wright JJ, Hirst J
J Biol Chem (2021) 296 pp. 100474-100474 [ DOI: doi:10.1016/j.jbc.2021.100474 Pubmed: 33640456 ]
- Subunit nidm of nadh:ubiquinone oxidoreductase (complex i) (11 kDa, Protein from Yarrowia lipolytica)
- Subunit nuam of nadh:ubiquinone oxidoreductase (complex i) (79 kDa, Protein from Yarrowia lipolytica)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Subunit nipm of nadh:ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Yarrowia lipolytica)
- Subunit nb2m of nadh:ubiquinone oxidoreductase (complex i) (6 kDa, Protein from Yarrowia lipolytica)
- Nucm protein (52 kDa, Protein from Yarrowia lipolytica)
- Yarrowia lipolytica mitochondrial complex i (nadh:ubiquinone oxidoreductase) with nucm r121m mutation (Complex from Yarrowia lipolytica)
- Subunit nuxm of nadh:ubiquinone oxidoreductase (complex i) (18 kDa, Protein from Yarrowia lipolytica)
- Subunit nb4m of protein nadh:ubiquinone oxidoreductase (complex i) (14 kDa, Protein from Yarrowia lipolytica)
- Nugm protein (33 kDa, Protein from Yarrowia lipolytica)
- Complex i-b14.7 (18 kDa, Protein from Yarrowia lipolytica)
- Diundecyl phosphatidyl choline (622 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 4 (54 kDa, Protein from Yarrowia lipolytica)
- Subunit nupm of nadh:ubiquinone oxidoreductase (complex i) (19 kDa, Protein from Yarrowia lipolytica)
- Subunit nuhm of nadh:ubiquinone oxidoreductase (complex i) (27 kDa, Protein from Yarrowia lipolytica)
- Subunit nebm of protein nadh:ubiquinone oxidoreductase (complex i) [yarrowia lipolytica] (7 kDa, Protein from Yarrowia lipolytica)
- Subunit nufm of nadh:ubiquinone oxidoreductase (complex i) (16 kDa, Protein from Yarrowia lipolytica)
- Nadh-ubiquinone oxidoreductase chain 3 (14 kDa, Protein from Yarrowia lipolytica)
- Subunit nb8m of nadh:ubiquinone oxidoreductase (complex i) (11 kDa, Protein from Yarrowia lipolytica)
- Nadh-ubiquinone oxidoreductase chain 5 (73 kDa, Protein from Yarrowia lipolytica)
- Dodecyl-beta-d-maltoside (510 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 1 (38 kDa, Protein from Yarrowia lipolytica)
- Subunit nuim of protein nadh:ubiquinone oxidoreductase (complex i) (21 kDa, Protein from Yarrowia lipolytica)
- Nadh-ubiquinone oxidoreductase chain 6 (20 kDa, Protein from Yarrowia lipolytica)
- Subunit nuym of nadh:ubiquinone oxidoreductase (complex i) (18 kDa, Protein from Yarrowia lipolytica)
- Zf-chcc domain-containing protein (13 kDa, Protein from Yarrowia lipolytica)
- Grim-19 (13 kDa, Protein from Yarrowia lipolytica)
- Subunit nuzm of nadh:ubiquinone oxidoreductase (complex i) (19 kDa, Protein from Yarrowia lipolytica)
- Subunit ni9m of protein nadh:ubiquinone oxidoreductase (complex i) (8 kDa, Protein from Yarrowia lipolytica)
- Acyl carrier protein (8 kDa, Protein from Yarrowia lipolytica)
- Subunit n7bm of nadh:ubiquinone oxidoreductase (complex i) (16 kDa, Protein from Yarrowia lipolytica)
- Subunit nuvm of nadh:ubiquinone oxidoreductase (complex i) (7 kDa, Protein from Yarrowia lipolytica)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Subunit nuum of nadh:ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Yarrowia lipolytica)
- Subunit ni8m of nadh:ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Yarrowia lipolytica)
- Nadh dehydrogenase subunit 2 (53 kDa, Protein from Yarrowia lipolytica)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Flavin mononucleotide (456 Da, Ligand)
- Epimerase domain-containing protein (40 kDa, Protein from Yarrowia lipolytica)
- Acyl carrier protein (9 kDa, Protein from Yarrowia lipolytica)
- Subunit ni2m of nadh:ubiquinone oxidoreductase (complex i) (12 kDa, Protein from Yarrowia lipolytica)
- Subunit nubm of nadh:ubiquinone oxidoreductase (complex i) (53 kDa, Protein from Yarrowia lipolytica)
- Subunit niam of nadh:ubiquinone oxidoreductase (complex i) (17 kDa, Protein from Yarrowia lipolytica)
- Subunit nukm of nadh:ubiquinone oxidoreductase (complex i) (23 kDa, Protein from Yarrowia lipolytica)
- Subunit nesm of nadh:ubiquinone oxidoreductase (complex i) (28 kDa, Protein from Yarrowia lipolytica)
- ~{s}-[2-[3-[[(2~{r})-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl] (3~{s})-3-oxidanyltetradecanethioate (584 Da, Ligand)
- Iron/sulfur cluster (351 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 4l (9 kDa, Protein from Yarrowia lipolytica)
- Cardiolipin (1 kDa, Ligand)
- Subunit nunm of protein nadh:ubiquinone oxidoreductase (complex i) (15 kDa, Protein from Yarrowia lipolytica)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (9 kDa, Protein from Yarrowia lipolytica)
- Subunit nb5m of nadh:ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Yarrowia lipolytica)
Complex I during turnover, open3
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 6zkf
Q-score: 0.564
Science (2020) 370 [ Pubmed: 32972993 DOI: doi:10.1126/science.abc4209 ]
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Sheep)
- Iron/sulfur cluster (351 Da, Ligand)
- Mitochondrial complex i, pdsw subunit (20 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Sheep)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Mitochondrial complex i, b16.6 subunit (16 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit a9 (43 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b3 (11 kDa, Protein from Sheep)
- Mitochondrial complex i, esss subunit (17 kDa, Protein from Sheep)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Mitochondrial complex i, mnll subunit (7 kDa, Protein from Sheep)
- 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione (322 Da, Ligand)
- Flavin mononucleotide (456 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Sheep)
- Acyl carrier protein (17 kDa, Protein from Sheep)
- Mitochondrial complex i, b14.7 subunit (14 kDa, Protein from Sheep)
- Mitochondrial complex i, b14.5a subunit (12 kDa, Protein from Sheep)
- Potassium ion (39 Da, Ligand)
- Mitochondrial complex i, b13 subunit (13 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b4 (15 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Sheep)
- Mitochondrial complex i, b17 subunit (15 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b7 (16 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from Sheep)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Nadh:ubiquinone oxidoreductase core subunit s1 (79 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit a6 (16 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit s5 (12 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (11 kDa, Protein from Sheep)
- Complex i during turnover, open3 (1 MDa, Complex from Ovis aries)
- Cardiolipin (1 kDa, Ligand)
- Mitochondrial complex i, 49 kda subunit (52 kDa, Protein from Sheep)
- Mitochondrial complex i, tyky subunit (24 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 4 (52 kDa, Protein from Sheep)
- Mitochondrial complex i, 13 kda subunit (13 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase core subunit s3 (30 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Sheep)
- Mitochondrial complex i, mwfe subunit (8 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Sheep)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Adenosine monophosphate (347 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Mitochondrial complex i, 24 kda subunit (27 kDa, Protein from Sheep)
- Myristic acid (228 Da, Ligand)
- Nadh:ubiquinone oxidoreductase subunit b2 (12 kDa, Protein from Sheep)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Mitochondrial complex i, psst subunit (24 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b5 (21 kDa, Protein from Sheep)
- Mitochondrial complex i, kfyi subunit (8 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Sheep)
- Mitochondrial complex i, 10 kda subunit (11 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit a3 (9 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b9 (21 kDa, Protein from Sheep)
- 1,2-diacyl-sn-glycero-3-phosphoethanolamine (748 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Sheep)
Membrane domain of open complex I during turnover
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 6zka
Q-score: 0.643
Science (2020) 370 [ Pubmed: 32972993 DOI: doi:10.1126/science.abc4209 ]
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Sheep)
- Mitochondrial complex i, pdsw subunit (20 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Sheep)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Membrane domain of open complex i during turnover (1 MDa, Complex from Ovis aries)
- Mitochondrial complex i, b16.6 subunit (16 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b3 (11 kDa, Protein from Sheep)
- Mitochondrial complex i, esss subunit (17 kDa, Protein from Sheep)
- Mitochondrial complex i, nd4l subunit (52 kDa, Protein from Sheep)
- Mitochondrial complex i, mnll subunit (7 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Sheep)
- Acyl carrier protein (17 kDa, Protein from Sheep)
- Mitochondrial complex i, b14.7 subunit (14 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b4 (15 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Sheep)
- Mitochondrial complex i, b17 subunit (15 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b7 (16 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from Sheep)
- Water (18 Da, Ligand)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Nadh:ubiquinone oxidoreductase subunit s5 (12 kDa, Protein from Sheep)
- Cardiolipin (1 kDa, Ligand)
- Nadh-ubiquinone oxidoreductase chain 4 (52 kDa, Protein from Sheep)
- Mitochondrial complex i, mwfe subunit (8 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from Sheep)
- Adenosine monophosphate (347 Da, Ligand)
- Myristic acid (228 Da, Ligand)
- Nadh:ubiquinone oxidoreductase subunit b2 (12 kDa, Protein from Sheep)
- 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione (322 Da, Ligand from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b5 (21 kDa, Protein from Sheep)
- Mitochondrial complex i, kfyi subunit (8 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit a3 (9 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b9 (21 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Sheep)
- 1,2-diacyl-sn-glycero-3-phosphoethanolamine (748 Da, Ligand)
Membrane domain of closed complex I during turnover
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 6zkb
Q-score: 0.551
Science (2020) 370 [ Pubmed: 32972993 DOI: doi:10.1126/science.abc4209 ]
- Membrane domain of closed complex i during turnover (1 MDa, Complex from Ovis aries)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Sheep)
- Mitochondrial complex i, pdsw subunit (20 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Sheep)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Mitochondrial complex i, b16.6 subunit (16 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b3 (11 kDa, Protein from Sheep)
- Mitochondrial complex i, esss subunit (17 kDa, Protein from Sheep)
- Mitochondrial complex i, mnll subunit (7 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Sheep)
- Acyl carrier protein (17 kDa, Protein from Sheep)
- Mitochondrial complex i, b14.7 subunit (14 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b4 (15 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Sheep)
- Mitochondrial complex i, b17 subunit (15 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b7 (16 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from Sheep)
- Water (18 Da, Ligand)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Mitochondrial complex i, 49 kda subunit (52 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit s5 (12 kDa, Protein from Sheep)
- Cardiolipin (1 kDa, Ligand)
- Nadh-ubiquinone oxidoreductase chain 4 (52 kDa, Protein from Sheep)
- Mitochondrial complex i, mwfe subunit (8 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from Sheep)
- Adenosine monophosphate (347 Da, Ligand)
- Myristic acid (228 Da, Ligand)
- Nadh:ubiquinone oxidoreductase subunit b2 (12 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b5 (21 kDa, Protein from Sheep)
- Mitochondrial complex i, kfyi subunit (8 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit a3 (9 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b9 (21 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Sheep)
- 1,2-diacyl-sn-glycero-3-phosphoethanolamine (748 Da, Ligand)
Complex I during turnover, closed
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6zkc
Q-score: 0.523
Science (2020) 370 [ Pubmed: 32972993 DOI: doi:10.1126/science.abc4209 ]
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Sheep)
- Iron/sulfur cluster (351 Da, Ligand)
- Mitochondrial complex i, pdsw subunit (20 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Sheep)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Mitochondrial complex i, b16.6 subunit (16 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit a9 (43 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b3 (11 kDa, Protein from Sheep)
- Mitochondrial complex i, esss subunit (17 kDa, Protein from Sheep)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Mitochondrial complex i, mnll subunit (7 kDa, Protein from Sheep)
- 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione (322 Da, Ligand)
- Flavin mononucleotide (456 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Sheep)
- Acyl carrier protein (17 kDa, Protein from Sheep)
- Mitochondrial complex i, b14.7 subunit (14 kDa, Protein from Sheep)
- Mitochondrial complex i, b14.5a subunit (12 kDa, Protein from Sheep)
- Potassium ion (39 Da, Ligand)
- Mitochondrial complex i, b13 subunit (13 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b4 (15 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Sheep)
- Mitochondrial complex i, b17 subunit (15 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b7 (16 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from Sheep)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Nadh:ubiquinone oxidoreductase core subunit s1 (79 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit a6 (16 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit s5 (12 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (11 kDa, Protein from Sheep)
- Cardiolipin (1 kDa, Ligand)
- Mitochondrial complex i, 49 kda subunit (52 kDa, Protein from Sheep)
- Mitochondrial complex i, tyky subunit (24 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 4 (52 kDa, Protein from Sheep)
- Mitochondrial complex i, 13 kda subunit (13 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase core subunit s3 (30 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Sheep)
- Mitochondrial complex i, mwfe subunit (8 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Sheep)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Adenosine monophosphate (347 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Complex i during turnover, closed (1 MDa, Complex from Ovis aries)
- Mitochondrial complex i, 24 kda subunit (27 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b2 (12 kDa, Protein from Sheep)
- Myristic acid (228 Da, Ligand)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Mitochondrial complex i, psst subunit (24 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b5 (21 kDa, Protein from Sheep)
- Mitochondrial complex i, kfyi subunit (8 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Sheep)
- Mitochondrial complex i, 10 kda subunit (11 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit a3 (9 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b9 (21 kDa, Protein from Sheep)
- 1,2-diacyl-sn-glycero-3-phosphoethanolamine (748 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Sheep)
Complex I during turnover, open1
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 6zkd
Q-score: 0.579
Science (2020) 370 [ Pubmed: 32972993 DOI: doi:10.1126/science.abc4209 ]
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Sheep)
- Iron/sulfur cluster (351 Da, Ligand)
- Complex i during turnover, open1 (1 MDa, Complex from Ovis aries)
- Mitochondrial complex i, pdsw subunit (20 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Sheep)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Mitochondrial complex i, b16.6 subunit (16 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit a9 (43 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b3 (11 kDa, Protein from Sheep)
- Mitochondrial complex i, esss subunit (17 kDa, Protein from Sheep)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Mitochondrial complex i, mnll subunit (7 kDa, Protein from Sheep)
- 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione (322 Da, Ligand)
- Flavin mononucleotide (456 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Sheep)
- Acyl carrier protein (17 kDa, Protein from Sheep)
- Mitochondrial complex i, b14.7 subunit (14 kDa, Protein from Sheep)
- Mitochondrial complex i, b14.5a subunit (12 kDa, Protein from Sheep)
- Potassium ion (39 Da, Ligand)
- Mitochondrial complex i, b13 subunit (13 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b4 (15 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Sheep)
- Mitochondrial complex i, b17 subunit (15 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b7 (16 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from Sheep)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Nadh:ubiquinone oxidoreductase core subunit s1 (79 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit a6 (16 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit s5 (12 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (11 kDa, Protein from Sheep)
- Cardiolipin (1 kDa, Ligand)
- Mitochondrial complex i, 49 kda subunit (52 kDa, Protein from Sheep)
- Mitochondrial complex i, tyky subunit (24 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 4 (52 kDa, Protein from Sheep)
- Mitochondrial complex i, 13 kda subunit (13 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase core subunit s3 (30 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Sheep)
- Mitochondrial complex i, mwfe subunit (8 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Sheep)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Adenosine monophosphate (347 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Mitochondrial complex i, 24 kda subunit (27 kDa, Protein from Sheep)
- Myristic acid (228 Da, Ligand)
- Nadh:ubiquinone oxidoreductase subunit b2 (12 kDa, Protein from Sheep)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Mitochondrial complex i, psst subunit (24 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b5 (21 kDa, Protein from Sheep)
- Mitochondrial complex i, kfyi subunit (8 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Sheep)
- Mitochondrial complex i, 10 kda subunit (11 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit a3 (9 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b9 (21 kDa, Protein from Sheep)
- 1,2-diacyl-sn-glycero-3-phosphoethanolamine (748 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Sheep)
Complex I during turnover, open2
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 6zke
Q-score: 0.598
Science (2020) 370 [ Pubmed: 32972993 DOI: doi:10.1126/science.abc4209 ]
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Sheep)
- Iron/sulfur cluster (351 Da, Ligand)
- Mitochondrial complex i, pdsw subunit (20 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Sheep)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Mitochondrial complex i, b16.6 subunit (16 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit a9 (43 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b3 (11 kDa, Protein from Sheep)
- Mitochondrial complex i, esss subunit (17 kDa, Protein from Sheep)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Mitochondrial complex i, mnll subunit (7 kDa, Protein from Sheep)
- 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione (322 Da, Ligand)
- Flavin mononucleotide (456 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Sheep)
- Complex i during turnover, open2 (1 MDa, Complex from Ovis aries)
- Acyl carrier protein (17 kDa, Protein from Sheep)
- Mitochondrial complex i, b14.7 subunit (14 kDa, Protein from Sheep)
- Mitochondrial complex i, b14.5a subunit (12 kDa, Protein from Sheep)
- Potassium ion (39 Da, Ligand)
- Mitochondrial complex i, b13 subunit (13 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b4 (15 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Sheep)
- Mitochondrial complex i, b17 subunit (15 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b7 (16 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from Sheep)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Nadh:ubiquinone oxidoreductase core subunit s1 (79 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit a6 (16 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit s5 (12 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (11 kDa, Protein from Sheep)
- Cardiolipin (1 kDa, Ligand)
- Mitochondrial complex i, 49 kda subunit (52 kDa, Protein from Sheep)
- Mitochondrial complex i, tyky subunit (24 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 4 (52 kDa, Protein from Sheep)
- Mitochondrial complex i, 13 kda subunit (13 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase core subunit s3 (30 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Sheep)
- Mitochondrial complex i, mwfe subunit (8 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Sheep)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Adenosine monophosphate (347 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Mitochondrial complex i, 24 kda subunit (27 kDa, Protein from Sheep)
- Myristic acid (228 Da, Ligand)
- Nadh:ubiquinone oxidoreductase subunit b2 (12 kDa, Protein from Sheep)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Mitochondrial complex i, psst subunit (24 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b5 (21 kDa, Protein from Sheep)
- Mitochondrial complex i, kfyi subunit (8 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Sheep)
- Mitochondrial complex i, 10 kda subunit (11 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit a3 (9 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b9 (21 kDa, Protein from Sheep)
- 1,2-diacyl-sn-glycero-3-phosphoethanolamine (748 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Sheep)