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sample_name:"Complex I-MNLL" AND author_name:"O"
Cryo-EM structure of the I-II-III2-IV2 respiratory supercomplex from Tetrahymena thermophila
Release date: Aug. 23, 2023
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8bqs
Q-score: 0.356
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8bqs
Q-score: 0.356
Muhleip A, Flygaard RK, Baradaran R, Haapanen O, Gruhl T, Tobiasson V, Marechal A, Sharma V, Amunts A
Nature (2023) 615 pp. 934-938 [ DOI: doi:10.1038/s41586-023-05817-y Pubmed: 36949187 ]
Sample:
- Cx9c domain-containing protein (28 kDa, Protein from Tetrahymena thermophila SB210)
- Uqcrtt2 (4 kDa, Protein from Tetrahymena thermophila SB210)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 1 (32 kDa, Protein from Tetrahymena thermophila SB210)
- Yflt domain-containing protein (19 kDa, Protein from Tetrahymena thermophila SB210)
- Lysozyme (12 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (23 kDa, Protein from Tetrahymena thermophila SB210)
- Chch domain-containing protein (13 kDa, Protein from Tetrahymena thermophila SB210)
- Apocytochrome b (50 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh-ubiquinone oxidoreductase 75 kda subunit (80 kDa, Protein from Tetrahymena thermophila SB210)
- Potassium ion (39 Da, Ligand)
- Transmembrane protein, putative (18 kDa, Protein from Tetrahymena thermophila SB210)
- Ndub4 (14 kDa, Protein from Tetrahymena thermophila SB210)
- Carrier protein (37 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein (20 kDa, Protein from Tetrahymena thermophila SB210)
- Diphthamide synthesis protein (22 kDa, Protein from Tetrahymena thermophila SB210)
- Chromosome condensation regulator rcc1 repeat protein,chromosome condensation regulator rcc1 repeat protein,chromosome condensation regulator rcc1 repeat protein,chromosome condensation regulator rcc1 repeat protein,chain 150 (50 kDa, Protein from Tetrahymena thermophila SB210)
- Flavin-adenine dinucleotide (785 Da, Ligand)
- Acyl-coa synthetase (amp-forming)/amp-acid ligase ii (36 kDa, Protein from Tetrahymena thermophila SB210)
- Thioredoxin (19 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (24 kDa, Protein from Tetrahymena thermophila SB210)
- Rnase iii domain-containing protein (35 kDa, Protein from Tetrahymena thermophila SB210)
- Dnaj domain protein (36 kDa, Protein from Tetrahymena thermophila SB210)
- Coxtt22 (17 kDa, Protein from Tetrahymena thermophila SB210)
- Surf1-like protein (47 kDa, Protein from Tetrahymena thermophila SB210)
- Coxtt10 (28 kDa, Protein from Tetrahymena thermophila SB210)
- Zinc-finger protein (15 kDa, Protein from Tetrahymena thermophila SB210)
- Ribosomal protein l51/s25/ci-b8 domain protein (12 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (7 kDa, Protein from Tetrahymena thermophila SB210)
- Transcription factor apfi protein, putative (39 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (57 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh-ubiquinone oxidoreductase chain 3 (14 kDa, Protein from Tetrahymena thermophila SB210)
- 2 iron, 2 sulfur cluster-binding protein (19 kDa, Protein from Tetrahymena thermophila SB210)
- Tim10/ddp family zinc finger protein (8 kDa, Protein from Tetrahymena thermophila SB210)
- Cytochrome c oxidase subunit 1 (80 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (18 kDa, Protein from Tetrahymena thermophila SB210)
- Zf-tim10_ddp domain-containing protein (8 kDa, Protein from Tetrahymena thermophila SB210)
- Fe3-s4 cluster (295 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Nadh-ubiquinone oxidoreductase 1, chain, putative (28 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (15 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (8 kDa, Protein from Tetrahymena thermophila SB210)
- Ndub8 (24 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase subunit 1 (7 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8, mitochondrial (37 kDa, Protein from Tetrahymena thermophila SB210)
- Peptidase m16 inactive domain protein (58 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (52 kDa, Protein from Tetrahymena thermophila SB210)
- Coxtt9 (29 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (20 kDa, Protein from Tetrahymena thermophila SB210)
- Ctf/nf-i domain-containing protein (116 kDa, Protein from Tetrahymena thermophila SB210)
- Coxtt27 (23 kDa, Protein from Tetrahymena thermophila SB210)
- Iron-binding zinc finger cdgsh type protein (21 kDa, Protein from Tetrahymena thermophila SB210)
- Ymf75 (23 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase subunit 9 (23 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (7 kDa, Protein from Tetrahymena thermophila SB210)
- 39s ribosomal protein l9, mitochondrial (27 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (35 kDa, Protein from Tetrahymena thermophila SB210)
- Ubiquinol-cytochrome c reductase hinge protein (9 kDa, Protein from Tetrahymena thermophila SB210)
- Heme c (618 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Transmembrane protein, putative (41 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (28 kDa, Protein from Tetrahymena thermophila SB210)
- Dinuclear copper ion (127 Da, Ligand)
- Transmembrane protein, putative (14 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (29 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein (7 kDa, Protein from Tetrahymena thermophila SB210)
- 37s ribosomal protein s25, mitochondrial (33 kDa, Protein from Tetrahymena thermophila SB210)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Transmembrane protein, putative (15 kDa, Protein from Tetrahymena thermophila SB210)
- Ymf68 (72 kDa, Protein from Tetrahymena thermophila SB210)
- Phage protein (14 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase subunit 7 (51 kDa, Protein from Tetrahymena thermophila SB210)
- M16 family peptidase, putative (53 kDa, Protein from Tetrahymena thermophila SB210)
- Ph domain-containing protein (15 kDa, Protein from Tetrahymena thermophila SB210)
- Annexin (8 kDa, Protein from Tetrahymena thermophila SB210)
- Protein phosphatase 2c, putative (53 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (24 kDa, Protein from Tetrahymena thermophila SB210)
- Etc complex i subunit motif protein (24 kDa, Protein from Tetrahymena thermophila SB210)
- Ymf67 (54 kDa, Protein from Tetrahymena thermophila SB210)
- Surf1-like protein (35 kDa, Protein from Tetrahymena thermophila SB210)
- Nad-dependent epimerase/dehydratase family protein (41 kDa, Protein from Tetrahymena thermophila SB210)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Trab family protein (45 kDa, Protein from Tetrahymena thermophila SB210)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Ndutt10 (14 kDa, Protein from Tetrahymena thermophila SB210)
- Ndub6 (15 kDa, Protein from Tetrahymena thermophila SB210)
- Uqcrtt3 (5 kDa, Protein from Tetrahymena thermophila SB210)
- Ndutt11 (15 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (14 kDa, Protein from Tetrahymena thermophila SB210)
- 2-oxoglutarate/malate carrier protein (36 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (15 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (11 kDa, Protein from Tetrahymena thermophila SB210)
- Mobilization protein (23 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh-ubiquinone oxidoreductase chain 4 (58 kDa, Protein from Tetrahymena thermophila SB210)
- Gamma-carbonic anhydrase (25 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (12 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (26 kDa, Protein from Tetrahymena thermophila SB210)
- Ymf58 (13 kDa, Protein from Tetrahymena thermophila SB210)
- Cytochrome c oxidase subunit vb protein (75 kDa, Protein from Tetrahymena thermophila SB210)
- Acyl carrier protein (15 kDa, Protein from Tetrahymena thermophila SB210)
- Copper (ii) ion (63 Da, Ligand)
- Cullin domain-containing protein (8 kDa, Protein from Tetrahymena thermophila SB210)
- Uridine-5'-diphosphate (404 Da, Ligand)
- Structural protein (27 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (9 kDa, Protein from Tetrahymena thermophila SB210)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Cytochrome c oxidase subunit 2 (72 kDa, Protein from Tetrahymena thermophila SB210)
- Ymf65 (43 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase, putative (20 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (8 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein (24 kDa, Protein from Tetrahymena thermophila SB210)
- Rieske iron-sulfur protein, ubiquinol-cytochrome c reductase iron-sulfur subunit (30 kDa, Protein from Tetrahymena thermophila SB210)
- Heme-a (852 Da, Ligand)
- Complex i-mnll (12 kDa, Protein from Tetrahymena thermophila SB210)
- Magnesium ion (24 Da, Ligand)
- Atp synthase subunit e, mitochondrial (11 kDa, Protein from Tetrahymena thermophila SB210)
- Abc transporter (10 kDa, Protein from Tetrahymena thermophila SB210)
- Uqcrtt1 (39 kDa, Protein from Tetrahymena thermophila SB210)
- Ubiquinone-8 (727 Da, Ligand)
- Flavin mononucleotide (456 Da, Ligand)
- Transposase (8 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (16 kDa, Protein from Tetrahymena thermophila SB210)
- Cox assembly mitochondrial protein (17 kDa, Protein from Tetrahymena thermophila SB210)
- Gram domain protein (10 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (16 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase subunit 10 (18 kDa, Protein from Tetrahymena thermophila SB210)
- Decapping nuclease (10 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (9 kDa, Protein from Tetrahymena thermophila SB210)
- Transposase (11 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase subunit 5 (88 kDa, Protein from Tetrahymena thermophila SB210)
- Sdhtt11 (5 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (15 kDa, Protein from Tetrahymena thermophila SB210)
- Oxoglutarate/malate translocator protein, putative (40 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase subunit 2 (20 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh-ubiquinone oxidoreductase 24 kda subunit (31 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (22 kDa, Protein from Tetrahymena thermophila SB210)
- Succinate dehydrogenase (36 kDa, Protein from Tetrahymena thermophila SB210)
- Zf-tim10_ddp domain-containing protein (10 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (22 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh-ubiquinone oxidoreductase complex i, 21 kda subunit (17 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (13 kDa, Protein from Tetrahymena thermophila SB210)
- Duf4885 domain-containing protein (12 kDa, Protein from Tetrahymena thermophila SB210)
- Acyl carrier protein (16 kDa, Protein from Tetrahymena thermophila SB210)
- Lipid-a-disaccharide synthase (59 kDa, Protein from Tetrahymena thermophila SB210)
- 2-(hexadecanoyloxy)-1-[(phosphonooxy)methyl]ethyl hexadecanoate (648 Da, Ligand)
- Ndub10 (22 kDa, Protein from Tetrahymena thermophila SB210)
- Ymf70 (10 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (15 kDa, Protein from Tetrahymena thermophila SB210)
- Gamma-carbonic anhydrase (28 kDa, Protein from Tetrahymena thermophila SB210)
- Ndutt12 (13 kDa, Protein from Tetrahymena thermophila SB210)
- Complex iii subunit vii (19 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (26 kDa, Protein from Tetrahymena thermophila SB210)
- Nduph2 (22 kDa, Protein from Tetrahymena thermophila SB210)
- Nmra domain-containing protein (36 kDa, Protein from Tetrahymena thermophila SB210)
- Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (70 kDa, Protein from Tetrahymena thermophila SB210)
- Nd5a (25 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (11 kDa, Protein from Tetrahymena thermophila SB210)
- Ymf62 (30 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (21 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (11 kDa, Protein from Tetrahymena thermophila SB210)
- Succinate dehydrogenase complex iron-sulfur subunit d (5 kDa, Protein from Tetrahymena thermophila SB210)
- Ymf57 (12 kDa, Protein from Tetrahymena thermophila SB210)
- Respiratory chain supercomplex from the ciliate tetrahymena thermophila (Complex from Tetrahymena thermophila SB210)
- Ndua13 (21 kDa, Protein from Tetrahymena thermophila SB210)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Chain 77 (23 kDa, Protein from Tetrahymena thermophila SB210)
- Coxtt12,transmembrane protein,transmembrane protein,transmembrane protein (25 kDa, Protein from Tetrahymena thermophila SB210)
- Iron/sulfur cluster (351 Da, Ligand)
- Cardiolipin (1 kDa, Ligand)
- Coxtt28 (11 kDa, Protein from Tetrahymena thermophila SB210)
- Cytochrome protein c1 (37 kDa, Protein from Tetrahymena thermophila SB210)
Release date: March 29, 2023
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8b6f
Q-score: 0.463
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8b6f
Q-score: 0.463
Muhleip A, Flygaard RK, Baradaran R, Haapanen O, Gruhl T, Tobiasson V, Marechal A, Sharma V, Amunts A
Nature (2023) 615 pp. 934-938 [ DOI: doi:10.1038/s41586-023-05817-y Pubmed: 36949187 ]
Sample:
- Cx9c domain-containing protein (28 kDa, Protein from Tetrahymena thermophila SB210)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 1 (32 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (23 kDa, Protein from Tetrahymena thermophila SB210)
- Chch domain-containing protein (13 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh-ubiquinone oxidoreductase 75 kda subunit (80 kDa, Protein from Tetrahymena thermophila SB210)
- Ndub4 (14 kDa, Protein from Tetrahymena thermophila SB210)
- Acyl-coa synthetase (amp-forming)/amp-acid ligase ii (36 kDa, Protein from Tetrahymena thermophila SB210)
- Thioredoxin (19 kDa, Protein from Tetrahymena thermophila SB210)
- Rnase iii domain-containing protein (35 kDa, Protein from Tetrahymena thermophila SB210)
- Dnaj domain protein (36 kDa, Protein from Tetrahymena thermophila SB210)
- Zinc-finger protein (15 kDa, Protein from Tetrahymena thermophila SB210)
- Ribosomal protein l51/s25/ci-b8 domain protein (12 kDa, Protein from Tetrahymena thermophila SB210)
- Transcription factor apfi protein, putative (39 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh-ubiquinone oxidoreductase chain 3 (14 kDa, Protein from Tetrahymena thermophila SB210)
- 2 iron, 2 sulfur cluster-binding protein (19 kDa, Protein from Tetrahymena thermophila SB210)
- Zinc ion (65 Da, Ligand)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Nadh-ubiquinone oxidoreductase 1, chain, putative (28 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (8 kDa, Protein from Tetrahymena thermophila SB210)
- Ndub8 (24 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (52 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase subunit 9 (23 kDa, Protein from Tetrahymena thermophila SB210)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Transmembrane protein, putative (29 kDa, Protein from Tetrahymena thermophila SB210)
- 37s ribosomal protein s25, mitochondrial (33 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase subunit 7 (51 kDa, Protein from Tetrahymena thermophila SB210)
- Ph domain-containing protein (15 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh:ubiquinone oxidoreductase complex (complex-i) from respiratory supercomplex of tetrahymena thermophila (1 MDa, Complex from Tetrahymena thermophila)
- Etc complex i subunit motif protein (24 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (24 kDa, Protein from Tetrahymena thermophila SB210)
- Nad-dependent epimerase/dehydratase family protein (41 kDa, Protein from Tetrahymena thermophila SB210)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Ndub6 (15 kDa, Protein from Tetrahymena thermophila SB210)
- Ndutt17 (13 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (15 kDa, Protein from Tetrahymena thermophila SB210)
- Nd1b (7 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh-ubiquinone oxidoreductase chain 4 (58 kDa, Protein from Tetrahymena thermophila SB210)
- Gamma-carbonic anhydrase (25 kDa, Protein from Tetrahymena thermophila SB210)
- Ymf58 (13 kDa, Protein from Tetrahymena thermophila SB210)
- Acyl carrier protein (15 kDa, Protein from Tetrahymena thermophila SB210)
- Uridine-5'-diphosphate (404 Da, Ligand)
- Transmembrane protein, putative (9 kDa, Protein from Tetrahymena thermophila SB210)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Ndutt15 (25 kDa, Protein from Tetrahymena thermophila SB210)
- Ymf65 (43 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase, putative (20 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (8 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein (24 kDa, Protein from Tetrahymena thermophila SB210)
- Ndutt16 (15 kDa, Protein from Tetrahymena thermophila SB210)
- Complex i-mnll (12 kDa, Protein from Tetrahymena thermophila SB210)
- Magnesium ion (24 Da, Ligand)
- Atp synthase subunit e, mitochondrial (11 kDa, Protein from Tetrahymena thermophila SB210)
- Flavin mononucleotide (456 Da, Ligand)
- Transmembrane protein, putative (16 kDa, Protein from Tetrahymena thermophila SB210)
- Cox assembly mitochondrial protein (17 kDa, Protein from Tetrahymena thermophila SB210)
- Gram domain protein (10 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase subunit 10 (18 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase subunit 5 (88 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase subunit 2 (20 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh-ubiquinone oxidoreductase 24 kda subunit (31 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (22 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (22 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh-ubiquinone oxidoreductase complex i, 21 kda subunit (17 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (13 kDa, Protein from Tetrahymena thermophila SB210)
- Acyl carrier protein (16 kDa, Protein from Tetrahymena thermophila SB210)
- Lipid-a-disaccharide synthase (59 kDa, Protein from Tetrahymena thermophila SB210)
- 2-(hexadecanoyloxy)-1-[(phosphonooxy)methyl]ethyl hexadecanoate (648 Da, Ligand)
- Ndub10 (22 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (15 kDa, Protein from Tetrahymena thermophila SB210)
- Gamma-carbonic anhydrase (28 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (26 kDa, Protein from Tetrahymena thermophila SB210)
- Nduph2 (22 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (11 kDa, Protein from Tetrahymena thermophila SB210)
- Ymf62 (30 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (21 kDa, Protein from Tetrahymena thermophila SB210)
- Ymf57 (12 kDa, Protein from Tetrahymena thermophila SB210)
- Ndua13 (21 kDa, Protein from Tetrahymena thermophila SB210)
- Ndub15 (14 kDa, Protein from Tetrahymena thermophila SB210)
- Iron/sulfur cluster (351 Da, Ligand)
- Cardiolipin (1 kDa, Ligand)
Complex I from Ovis aries at pH5.5, Open state
Release date: Sept. 21, 2022
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 7zdj
Q-score: 0.547
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 7zdj
Q-score: 0.547
Kravchuk V, Petrova O, Kampjut D, Wojciechowska-Bason A, Breese Z, Sazanov L
Nature (2022) 609 pp. 808-814 [ DOI: doi:10.1038/s41586-022-05199-7 Pubmed: 36104567 ]
Sample:
- Complex i-pdsw (20 kDa, Protein from sheep)
- Complex i subunit b13 (13 kDa, Protein from sheep)
- Complex i-b14.7 (14 kDa, Protein from sheep)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Complex i-9kd (5 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (36 kDa, Protein from sheep)
- Complex i-b22 (21 kDa, Protein from sheep)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Complex i-aggg (7 kDa, Protein from sheep)
- Complex i-sgdh (16 kDa, Protein from sheep)
- Complex i-kfyi (5 kDa, Protein from sheep)
- Complex i-b12 (8 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (18 kDa, Protein from sheep)
- Complex i-b18 (14 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (14 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (9 kDa, Protein from sheep)
- Complex i-23kd (20 kDa, Protein from sheep)
- Nadh:ubiquinone oxidoreductase subunit b4 (14 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 4 (52 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from sheep)
- Complex i-b9 (8 kDa, Protein from sheep)
- Acyl carrier protein (17 kDa, Protein from sheep)
- Complex i-30kd (24 kDa, Protein from sheep)
- Potassium ion (39 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (47 kDa, Protein from sheep)
- Complex i from ovis aries at ph5.5, open state (1 MDa, Complex from Ovis aries)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from sheep)
- Complex i-49kd (52 kDa, Protein from sheep)
- Nadh:ubiquinone oxidoreductase subunit a9 (43 kDa, Protein from sheep)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Complex i-mnll (6 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (10 kDa, Protein from sheep)
- Mitochondrial complex i, b14.5a subunit (12 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from sheep)
- Complex i-mwfe (8 kDa, Protein from sheep)
- Complex i-20kd (17 kDa, Protein from sheep)
- Myristic acid (228 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from sheep)
- Flavin mononucleotide (456 Da, Ligand)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Complex i-b14 (13 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from sheep)
- Complex i-esss (11 kDa, Protein from sheep)
- Iron/sulfur cluster (351 Da, Ligand)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (75 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (23 kDa, Protein from sheep)
- Mitochondrial complex i, b17 subunit (15 kDa, Protein from sheep)
Complex I from Ovis aries at pH9, Open state
Release date: Sept. 21, 2022
Resolution: 3.88 Å
EM Method: Single-particle
Fitted PDBs: 7zdp
Q-score: 0.437
Resolution: 3.88 Å
EM Method: Single-particle
Fitted PDBs: 7zdp
Q-score: 0.437
Kravchuk V, Petrova O, Kampjut D, Wojciechowska-Bason A, Breese Z, Sazanov L
Nature (2022) 609 pp. 808-814 [ DOI: doi:10.1038/s41586-022-05199-7 Pubmed: 36104567 ]
Sample:
- Complex i-pdsw (20 kDa, Protein from sheep)
- Complex i subunit b13 (13 kDa, Protein from sheep)
- Complex i-b14.7 (14 kDa, Protein from sheep)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Complex i-9kd (5 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (36 kDa, Protein from sheep)
- Complex i from ovis aries at ph9, open state (1 MDa, Complex from Ovis aries)
- Complex i-b22 (21 kDa, Protein from sheep)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Complex i-aggg (7 kDa, Protein from sheep)
- Complex i-sgdh (16 kDa, Protein from sheep)
- Complex i-kfyi (5 kDa, Protein from sheep)
- Complex i-b12 (8 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (18 kDa, Protein from sheep)
- Complex i-b18 (14 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (14 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (9 kDa, Protein from sheep)
- Complex i-23kd (20 kDa, Protein from sheep)
- Nadh:ubiquinone oxidoreductase subunit b4 (14 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 4 (52 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from sheep)
- Complex i-b9 (8 kDa, Protein from sheep)
- Acyl carrier protein (17 kDa, Protein from sheep)
- Complex i-30kd (24 kDa, Protein from sheep)
- Potassium ion (39 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (47 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from sheep)
- Complex i-49kd (52 kDa, Protein from sheep)
- Nadh:ubiquinone oxidoreductase subunit a9 (43 kDa, Protein from sheep)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Adenosine monophosphate (347 Da, Ligand)
- Complex i-mnll (6 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (10 kDa, Protein from sheep)
- Mitochondrial complex i, b14.5a subunit (12 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from sheep)
- Complex i-mwfe (8 kDa, Protein from sheep)
- Complex i-20kd (17 kDa, Protein from sheep)
- Myristic acid (228 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from sheep)
- Flavin mononucleotide (456 Da, Ligand)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Complex i-b14 (13 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from sheep)
- Complex i-esss (11 kDa, Protein from sheep)
- Iron/sulfur cluster (351 Da, Ligand)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (75 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (23 kDa, Protein from sheep)
- Mitochondrial complex i, b17 subunit (15 kDa, Protein from sheep)
Complex I from Ovis aries at pH9, Closed state
Release date: Sept. 21, 2022
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7zeb
Q-score: 0.452
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7zeb
Q-score: 0.452
Kravchuk V, Petrova O, Kampjut D, Wojciechowska-Bason A, Breese Z, Sazanov L
Nature (2022) 609 pp. 808-814 [ DOI: doi:10.1038/s41586-022-05199-7 Pubmed: 36104567 ]
Sample:
- Complex i-pdsw (20 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (49 kDa, Protein from sheep)
- Complex i-b14.7 (14 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (13 kDa, Protein from sheep)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Complex i-9kd (5 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (36 kDa, Protein from sheep)
- Complex i-b22 (21 kDa, Protein from sheep)
- Nadh:ubiquinone oxidoreductase subunit a9 (38 kDa, Protein from sheep)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Complex i-aggg (7 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (14 kDa, Protein from sheep)
- Complex i-sgdh (16 kDa, Protein from sheep)
- Complex i-kfyi (5 kDa, Protein from sheep)
- Complex i-b12 (8 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (18 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (14 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (9 kDa, Protein from sheep)
- Nadh:ubiquinone oxidoreductase subunit b4 (14 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 4 (52 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from sheep)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Complex i-b9 (8 kDa, Protein from sheep)
- Acyl carrier protein (17 kDa, Protein from sheep)
- Complex i-30kd (24 kDa, Protein from sheep)
- Potassium ion (39 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (17 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (47 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from sheep)
- Complex i-23kd (24 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from sheep)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Adenosine monophosphate (347 Da, Ligand)
- Complex i-mnll (6 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (10 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from sheep)
- Complex i-mwfe (8 kDa, Protein from sheep)
- Myristic acid (228 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from sheep)
- Flavin mononucleotide (456 Da, Ligand)
- Complex i-b14 (13 kDa, Protein from sheep)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from sheep)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Complex i-esss (11 kDa, Protein from sheep)
- Iron/sulfur cluster (351 Da, Ligand)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (75 kDa, Protein from sheep)
- Complex i from ovis aries at ph9, closed state (1 MDa, Complex from Ovis aries)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (23 kDa, Protein from sheep)