Human EBP complexed with compound 3a
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8w0s
Q-score: 0.558
Dorel R, Sun D, Carruthers N, Castanedo GM, Ung PM, Factor DC, Li T, Baumann H, Janota D, Pang J, Salphati L, Meklemburg R, Korman AJ, Harper HE, Stubblefield S, Payandeh J, McHugh D, Lang BT, Tesar PJ, Dere E, Masureel M, Adams DJ, Volgraf M, Braun MG
J Med Chem (2024) 67 pp. 4819-4832 [ Pubmed: 38470227 DOI: doi:10.1021/acs.jmedchem.3c02396 ]
Structural Basis of Human NOX5 Activation
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8u86
Q-score: 0.45
Cui C, Jiang M, Jain N, Das S, Lo YH, Kermani AA, Pipatpolkai T, Sun J
Nat Commun (2024) 15 pp. 3994-3994 [ DOI: doi:10.1038/s41467-024-48467-y Pubmed: 38734761 ]
- Zinc ion (65 Da, Ligand)
- Nadph oxidase 5 (82 kDa, Protein from Homo sapiens)
- Nadph oxidase 5 (Complex from Homo sapiens)
- Decane (142 Da, Ligand)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Heme b/c (618 Da, Ligand)
- Flavin-adenine dinucleotide (785 Da, Ligand)
- Dodecane (170 Da, Ligand)
Structural Basis of Human NOX5 Activation
Resolution: 4.06 Å
EM Method: Single-particle
Fitted PDBs: 8u7y
Q-score: 0.327
Cui C, Jiang M, Jain N, Das S, Lo YH, Kermani AA, Pipatpolkai T, Sun J
Nat Commun (2024) 15 pp. 3994-3994 [ DOI: doi:10.1038/s41467-024-48467-y Pubmed: 38734761 ]
- Zinc ion (65 Da, Ligand)
- Nadph oxidase 5 (82 kDa, Protein from Homo sapiens)
- Nadp nicotinamide-adenine-dinucleotide phosphate (743 Da, Ligand)
- Nadph oxidase 5 (Complex from Homo sapiens)
- Decane (142 Da, Ligand)
- Heme b/c (618 Da, Ligand)
- Flavin-adenine dinucleotide (785 Da, Ligand)
- Dodecane (170 Da, Ligand)
Resolution: 3.03 Å
EM Method: Single-particle
Fitted PDBs: 8b01
Q-score: 0.539
Davies JS, Currie MJ, North RA, Scalise M, Wright JD, Copping JM, Remus DM, Gulati A, Morado DR, Jamieson SA, Newton-Vesty MC, Abeysekera GS, Ramaswamy S, Friemann R, Wakatsuki S, Allison JR, Indiveri C, Drew D, Mace PD, Dobson RCJ
Nat Commun (2023) 14 pp. 1120-1120 [ Pubmed: 36849793 DOI: doi:10.1038/s41467-023-36590-1 ]
- Megabody c7hopq (54 kDa, Protein from synthetic construct)
- Docosane (310 Da, Ligand)
- Hexane (86 Da, Ligand)
- Putative trap-type c4-dicarboxylate transport system, large permease component (45 kDa, Protein from Photobacterium profundum SS9)
- Phosphatidylethanolamine (734 Da, Ligand)
- Putative trap-type c4-dicarboxylate transport system, small permease component (19 kDa, Protein from Photobacterium profundum SS9)
- Sodium ion (22 Da, Ligand)
- Tridecane (184 Da, Ligand)
- Decane (142 Da, Ligand)
- Siaqm (Complex from Photobacterium profundum)
- N-octane (114 Da, Ligand)
- Siaqm with megabody (Complex)
- Megabody (Complex from Helicobacter pylori)