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sample_name:"DNA-directed RNA polymerase II subunit RPB11" AND database:"EMDB"
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Paused elongation complex of mammalian RNA polymerase II with nucleosome (PEC2-nuc)

Release date: Feb. 5, 2025
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 9j0n
Q-score: 0.316

Naganuma M, Kujirai T, Ehara H, Uejima T, Ito T, Goto M, Aoki M, Henmi M, Miyamoto-Kohno S, Shirouzu M, Kurumizaka H, Sekine S

Sci Adv (2025) [ DOI: doi:10.1126/sciadv.adu0577 ]

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Arrested elongation complex of mammalian RNA polymerase II with nucleosome (AEC1-nuc)

Release date: Feb. 5, 2025
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 9j0o
Q-score: 0.313

Naganuma M, Kujirai T, Ehara H, Uejima T, Ito T, Goto M, Aoki M, Henmi M, Miyamoto-Kohno S, Shirouzu M, Kurumizaka H, Sekine S

Sci Adv (2025) [ DOI: doi:10.1126/sciadv.adu0577 ]

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Arrested elongation complex of mammalian RNA polymerase II with nucleosome (AEC2-nuc)

Release date: Feb. 5, 2025
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 9j0p
Q-score: 0.311

Naganuma M, Kujirai T, Ehara H, Uejima T, Ito T, Goto M, Aoki M, Henmi M, Miyamoto-Kohno S, Shirouzu M, Kurumizaka H, Sekine S

Sci Adv (2025) [ DOI: doi:10.1126/sciadv.adu0577 ]

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RNA polymerase II bound to Alu RNA right arm

RNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-SETD2-nucleosome, 20 bp upstream

Release date: Dec. 18, 2024
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 9eh1

Markert JW, Soffers JH, Farnung L

Science (2025) 387 pp. 528-533 [ Pubmed: 39666822 DOI: doi:10.1126/science.adn6319 ]

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RNA polymerase II bound to minimal Alu RNA right arm in the alternative conformation

PolII-TCR-STK19 structure.

Release date: Dec. 4, 2024
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 9er2
Q-score: 0.448

van den Heuvel D, Rodriguez-Martinez M, van der Meer PJ, Nieto Moreno N, Park J, Kim HS, van Schie JJM, Wondergem AP, D'Souza A, Yakoub G, Herlihy AE, Kashyap K, Boissiere T, Walker J, Mitter R, Apelt K, de Lint K, Kirdok I, Ljungman M, Wolthuis RMF, Cramer P, Scharer OD, Kokic G, Svejstrup JQ, Luijsterburg MS

Cell (2024) 187 pp. 7107- [ DOI: doi:10.1016/j.cell.2024.10.018 Pubmed: 39547229 ]

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Structure of Pol II-TC-NER-STK19 complex, consensus map

Release date: Nov. 13, 2024
Resolution: 4.2 Å
EM Method: Single-particle

Ramadhin AR, Lee SH, Zhou D, Salmazo A, Gonzalo-Hansen C, van Sluis M, Blom CMA, Janssens RC, Raams A, Dekkers D, Bezstarosti K, Slade D, Vermeulen W, Pines A, Demmers JAA, Bernecky C, Sixma TK, Marteijn JA

Mol Cell (2024) 84 pp. 4740-4757.e12 [ DOI: doi:10.1016/j.molcel.2024.10.030 Pubmed: 39547223 ]

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Structure of Pol II-TC-NER-STK19 complex, focused on Pol II-ELOF1

Release date: Nov. 13, 2024
Resolution: 3.0 Å
EM Method: Single-particle

Ramadhin AR, Lee SH, Zhou D, Salmazo A, Gonzalo-Hansen C, van Sluis M, Blom CMA, Janssens RC, Raams A, Dekkers D, Bezstarosti K, Slade D, Vermeulen W, Pines A, Demmers JAA, Bernecky C, Sixma TK, Marteijn JA

Mol Cell (2024) 84 pp. 4740-4757.e12 [ DOI: doi:10.1016/j.molcel.2024.10.030 Pubmed: 39547223 ]

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Structure of Pol II-TC-NER-STK19 complex, composite map

Release date: Nov. 13, 2024
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 9fd2
Q-score: 0.436

Ramadhin AR, Lee SH, Zhou D, Salmazo A, Gonzalo-Hansen C, van Sluis M, Blom CMA, Janssens RC, Raams A, Dekkers D, Bezstarosti K, Slade D, Vermeulen W, Pines A, Demmers JAA, Bernecky C, Sixma TK, Marteijn JA

Mol Cell (2024) 84 pp. 4740- [ DOI: doi:10.1016/j.molcel.2024.10.030 Pubmed: 39547223 ]

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