Bulky DNA lesion recognition complex 3
Kim J, Li CL, Chen X, Cui Y, Golebiowski FM, Wang H, Hanaoka F, Sugasawa K, Yang W
Nature (2023) 617 pp. 170-175 [ Pubmed: 37076618 DOI: doi:10.1038/s41586-023-05959-z ]
- Dna repair protein complementing xp-a cells (Protein from Homo sapiens)
- General transcription factor iih subunit 1 (Protein from Homo sapiens)
- Bulky dna lesion recognition complex 3 (440 kDa, Complex from Homo sapiens)
- Dna2 (DNA from synthetic construct)
- General transcription factor iih subunit 5 (Protein from Homo sapiens)
- General transcription factor iih subunit 2 (Protein from Homo sapiens)
- Tfiih basal transcription factor complex helicase xpd subunit (Protein from Homo sapiens)
- General transcription factor iih subunit 3 (Protein from Homo sapiens)
- Dna repair protein complementing xp-c cells (Protein from Homo sapiens)
- General transcription factor iih subunit 4 (Protein from Homo sapiens)
- Dna1 (DNA from synthetic construct)
- General transcription and dna repair factor iih helicase subunit xpb (Protein from Homo sapiens)
Initial DNA-lesion (Cy5) binding by XPC and TFIIH focused
Kim J, Li CL, Chen X, Cui Y, Golebiowski FM, Wang H, Hanaoka F, Sugasawa K, Yang W
Nature (2023) 617 pp. 170-175 [ Pubmed: 37076618 DOI: doi:10.1038/s41586-023-05959-z ]
- General transcription factor iih subunit 1 (Protein from Homo sapiens)
- Dna2 (DNA from synthetic construct)
- General transcription factor iih subunit 5 (Protein from Homo sapiens)
- Uv excision repair protein rad23 homolog b (Protein from Homo sapiens)
- General transcription factor iih subunit 2 (Protein from Homo sapiens)
- Tfiih basal transcription factor complex helicase xpd subunit (Protein from Homo sapiens)
- General transcription factor iih subunit 3 (Protein from Homo sapiens)
- Centrin-2 (Protein from Homo sapiens)
- Dna repair protein complementing xp-c cells (Protein from Homo sapiens)
- General transcription factor iih subunit 4 (Protein from Homo sapiens)
- Dna1 (DNA from synthetic construct)
- General transcription and dna repair factor iih helicase subunit xpb (Protein from Homo sapiens)
- Bulky dna lesion recognition complex 1 (270 kDa, Complex from Homo sapiens)
XPC release from Core7-XPA-DNA (Cy5)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8ebu
Q-score: 0.341
Kim J, Li CL, Chen X, Cui Y, Golebiowski FM, Wang H, Hanaoka F, Sugasawa K, Yang W
Nature (2023) 617 pp. 170-175 [ Pubmed: 37076618 DOI: doi:10.1038/s41586-023-05959-z ]
- General transcription factor iih subunit 3 (34 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Bulky dna lesion recognition complex3 (Complex from Homo sapiens)
- Tfiih basal transcription factor complex helicase xpb subunit (89 kDa, Protein from Homo sapiens)
- Dna repair protein complementing xp-c cells (107 kDa, Protein from Homo sapiens)
- General transcription factor iih subunit 5 (8 kDa, Protein from Homo sapiens)
- General transcription factor iih subunit 1 (62 kDa, Protein from Homo sapiens)
- Dna repair protein complementing xp-a cells (31 kDa, Protein from Homo sapiens)
- General transcription factor iih subunit 2 (46 kDa, Protein from Homo sapiens)
- General transcription and dna repair factor iih helicase subunit xpd (88 kDa, Protein from Homo sapiens)
- Iron/sulfur cluster (351 Da, Ligand)
- General transcription factor iih subunit 4, p52 (52 kDa, Protein from Homo sapiens)
- Dna1 (7 kDa, DNA from synthetic construct)
- Dna2 (7 kDa, DNA from synthetic construct)
Cryo-EM structure of mouse RAG1/2 NFC complex (DNA2)
Resolution: 3.29 Å
EM Method: Single-particle
Fitted PDBs: 6oer
Q-score: 0.464
Chen X, Cui Y, Best RB, Wang H, Zhou ZH, Yang W, Gellert M
Nat Struct Mol Biol (2020) 27 pp. 119-126 [ Pubmed: 32015552 DOI: doi:10.1038/s41594-019-0363-2 ]
- Zinc ion (65 Da, Ligand)
- Dna (57-mer) (18 kDa, DNA from Escherichia coli K-12)
- Calcium ion (40 Da, Ligand)
- V(d)j recombination-activating protein 1 (119 kDa, Protein from Mus musculus)
- V(d)j recombination-activating protein 2 (59 kDa, Protein from Mus musculus)
- Dna (57-mer) (18 kDa, DNA from Escherichia coli K-12)
- Dna (46-mer) (15 kDa, DNA from Escherichia coli K-12)
- High mobility group protein b1 (18 kDa, Protein from Equus caballus)
- Dna (46-mer) (15 kDa, DNA from Escherichia coli K-12)
- Rag1/2 nick-forming complex (dna2) (Complex)
