Structure of human oligosaccharyltransferase OST-A complex bound to NGI-1
Resolution: 3.61 Å
EM Method: Single-particle
Fitted PDBs: 8pn9
Q-score: 0.474
Lampson BL, Ramirez AS, Baro M, He L, Hegde M, Koduri V, Pfaff JL, Hanna RE, Kowal J, Shirole NH, He Y, Doench JG, Contessa JN, Locher KP, Kaelin Jr WG
Cell (2024) 187 pp. 2209-2223.e16 [ DOI: doi:10.1016/j.cell.2024.03.022 Pubmed: 38670073 ]
- (2~{s},3~{r},4~{r},5~{s},6~{s})-2-(hydroxymethyl)-6-[(1~{s},2~{r},3~{r},4~{r},5'~{s},6~{s},7~{r},8~{s},9~{r},12~{r},13~{r},15~{s},16~{s},18~{r})-5',7,9,13-tetramethyl-3,15-bis(oxidanyl)spiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosane-6,2'-oxane]-16-yl]oxy-oxane-3,4,5-triol (610 Da, Ligand)
- Water (18 Da, Ligand)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (69 kDa, Protein from Homo sapiens)
- Manganese (ii) ion (54 Da, Ligand)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4 (4 kDa, Protein from Homo sapiens)
- Transmembrane protein 258 (9 kDa, Protein from Homo sapiens)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kda subunit (50 kDa, Protein from Homo sapiens)
- (4r,7r)-4-hydroxy-n,n,n-trimethyl-4,9-dioxo-7-[(undecanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphadocosan-1-aminium (636 Da, Ligand)
- (2e,6e,10e,14e,18e,22e,26e)-3,7,11,15,19,23,27,31-octamethyldotriaconta-2,6,10,14,18,22,26,30-octaenyl trihydrogen diphosphate (722 Da, Ligand)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit stt3a (80 kDa, Protein from Homo sapiens)
- 5-(dimethylsulfamoyl)-~{n}-(5-methyl-1,3-thiazol-2-yl)-2-pyrrolidin-1-yl-benzamide (394 Da, Ligand)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit dad1 (12 kDa, Protein from Homo sapiens)
- Oligosaccharyltransferase complex subunit ostc (16 kDa, Protein from Homo sapiens)
- Oligosaccharyltransferase complex ost-a with bound ngi-1 inhibitor (Complex from Homo sapiens)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (68 kDa, Protein from Homo sapiens)
Outer kinetochore Dam1 protomer dimer Ndc80-Nuf2 coiled-coil complex
Resolution: 3.15 Å
EM Method: Single-particle
Fitted PDBs: 8q84
Q-score: 0.294
Muir KW, Batters C, Dendooven T, Yang J, Zhang Z, Burt A, Barford D
Science (2023) 382 pp. 1184-1190 [ DOI: doi:10.1126/science.adj8736 Pubmed: 38060647 ]
- Dash complex subunit dad1 (10 kDa, Protein from Saccharomyces cerevisiae)
- Dash complex subunit dad4 (8 kDa, Protein from Saccharomyces cerevisiae)
- Dash complex subunit spc19 (18 kDa, Protein from Saccharomyces cerevisiae)
- Dash complex subunit hsk3 (8 kDa, Protein from Saccharomyces cerevisiae)
- Outer kinetochore dam1 protomer dimer with staple and ndc80-nuf2 coiled-coils (673 GDa, Complex from Saccharomyces cerevisiae)
- Kinetochore protein nuf2 (53 kDa, Protein from Saccharomyces cerevisiae)
- Dash complex subunit duo1 (27 kDa, Protein from Saccharomyces cerevisiae)
- Dash complex subunit dam1 (38 kDa, Protein from Saccharomyces cerevisiae)
- Dash complex subunit spc34 (34 kDa, Protein from Saccharomyces cerevisiae)
- Kinetochore protein ndc80 (80 kDa, Protein from Saccharomyces cerevisiae)
- Dash complex subunit dad3 (10 kDa, Protein from Saccharomyces cerevisiae)
- Dash complex subunit ask1 (32 kDa, Protein from Saccharomyces cerevisiae)
- Dash complex subunit dad2 (15 kDa, Protein from Saccharomyces cerevisiae)
Outer kinetochore Dam1 protomer monomer Ndc80-Nuf2 coiled-coil complex
Resolution: 3.97 Å
EM Method: Single-particle
Fitted PDBs: 8q85
Q-score: 0.277
Muir KW, Batters C, Dendooven T, Yang J, Zhang Z, Burt A, Barford D
Science (2023) 382 pp. 1184-1190 [ DOI: doi:10.1126/science.adj8736 Pubmed: 38060647 ]
- Dash complex subunit dad1 (10 kDa, Protein from Saccharomyces cerevisiae)
- Dash complex subunit dad4 (8 kDa, Protein from Saccharomyces cerevisiae)
- Dash complex subunit spc19 (18 kDa, Protein from Saccharomyces cerevisiae)
- Dash complex subunit hsk3 (8 kDa, Protein from Saccharomyces cerevisiae)
- Kinetochore protein nuf2 (53 kDa, Protein from Saccharomyces cerevisiae)
- Dash complex subunit duo1 (27 kDa, Protein from Saccharomyces cerevisiae)
- Dash complex subunit dam1 (38 kDa, Protein from Saccharomyces cerevisiae)
- Outer kinetochore dam1 protomer monomer with staple and ndc80-nuf2 coiled-coils (673 GDa, Complex from Saccharomyces cerevisiae)
- Kinetochore protein ndc80 (80 kDa, Protein from Saccharomyces cerevisiae)
- Dash complex subunit dad3 (10 kDa, Protein from Saccharomyces cerevisiae)
- Dash complex subunit spc34 (34 kDa, Protein from Saccharomyces cerevisiae)
- Dash complex subunit ask1 (32 kDa, Protein from Saccharomyces cerevisiae)
- Dash complex subunit dad2 (15 kDa, Protein from Saccharomyces cerevisiae)
Subtomogram average of the human Sec61-TRAP-OSTA-translocon
Resolution: 7.6 Å
EM Method: Subtomogram averaging
Fitted PDBs: 8b6l
Q-score: 0.133
Gemmer M, Chaillet ML, van Loenhout J, Cuevas Arenas R, Vismpas D, Grollers-Mulderij M, Koh FA, Albanese P, Scheltema RA, Howes SC, Kotecha A, Fedry J, Forster F
Nature (2023) 614 pp. 160-167 [ Pubmed: 36697828 DOI: doi:10.1038/s41586-022-05638-5 ]
- Protein transport protein sec61 subunit beta (9 kDa, Protein from Homo sapiens)
- Translocon-associated protein subunit gamma (21 kDa, Protein from Homo sapiens)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kda subunit (50 kDa, Protein from Homo sapiens)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (69 kDa, Protein from Homo sapiens)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4 (4 kDa, Protein from Homo sapiens)
- Transmembrane protein 258 (9 kDa, Protein from Homo sapiens)
- Sec61-trap-osta translocon complex (Cellular component from Homo sapiens)
- Protein transport protein sec61 subunit gamma (7 kDa, Protein from Homo sapiens)
- Translocon-associated protein subunit delta (19 kDa, Protein from Homo sapiens)
- Protein transport protein sec61 subunit alpha isoform 1 (52 kDa, Protein from Homo sapiens)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit stt3a (80 kDa, Protein from Homo sapiens)
- Translocon-associated protein subunit alpha (32 kDa, Protein from Homo sapiens)
- Translocon-associated protein subunit beta (20 kDa, Protein from Homo sapiens)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit dad1 (12 kDa, Protein from Homo sapiens)
- Oligosaccharyltransferase complex subunit ostc (16 kDa, Protein from Homo sapiens)
- Signal peptide mix (1 kDa, Protein from Homo sapiens)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (68 kDa, Protein from Homo sapiens)
Cryo-EM structure of human oligosaccharyltransferase complex OST-A
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 6s7o
Q-score: 0.485
Ramirez AS, Kowal J, Locher KP
Science (2019) 366 pp. 1372-1375 [ Pubmed: 31831667 DOI: doi:10.1126/science.aaz3505 ]
- (2~{s},3~{r},4~{r},5~{s},6~{s})-2-(hydroxymethyl)-6-[(1~{s},2~{r},3~{r},4~{r},5'~{s},6~{s},7~{r},8~{s},9~{r},12~{r},13~{r},15~{s},16~{s},18~{r})-5',7,9,13-tetramethyl-3,15-bis(oxidanyl)spiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosane-6,2'-oxane]-16-yl]oxy-oxane-3,4,5-triol (610 Da, Ligand)
- Human oligosaccharyltransferase complex ost-a (Complex)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (69 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kda subunit (50 kDa, Protein from Homo sapiens)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4 (4 kDa, Protein from Homo sapiens)
- Transmembrane protein 258 (9 kDa, Protein from Homo sapiens)
- (4r,7r)-4-hydroxy-n,n,n-trimethyl-4,9-dioxo-7-[(undecanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphadocosan-1-aminium (636 Da, Ligand)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit stt3a (80 kDa, Protein from Homo sapiens)
- Human oligosaccharyltransferase complex (Complex from Homo sapiens)
- [(3~{r},6~{z},10~{z},14~{z},18~{z})-3,7,11,15,19,23-hexamethyltetracosa-6,10,14,18,22-pentaenyl] dihydrogen phosphate (508 Da, Ligand)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit dad1 (12 kDa, Protein from Homo sapiens)
- Oligosaccharyltransferase complex subunit ostc (16 kDa, Protein from Homo sapiens)
- Oligosaccharyltransferase complex subunit ostc (Complex from Homo sapiens)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (68 kDa, Protein from Homo sapiens)
Cryo-EM structure of human oligosaccharyltransferase complex OST-B
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 6s7t
Q-score: 0.509
Ramirez AS, Kowal J, Locher KP
Science (2019) 366 pp. 1372-1375 [ Pubmed: 31831667 DOI: doi:10.1126/science.aaz3505 ]
- (2~{s},3~{r},4~{r},5~{s},6~{s})-2-(hydroxymethyl)-6-[(1~{s},2~{r},3~{r},4~{r},5'~{s},6~{s},7~{r},8~{s},9~{r},12~{r},13~{r},15~{s},16~{s},18~{r})-5',7,9,13-tetramethyl-3,15-bis(oxidanyl)spiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosane-6,2'-oxane]-16-yl]oxy-oxane-3,4,5-triol (610 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (69 kDa, Protein from Homo sapiens)
- Magnesium transporter protein 1 (38 kDa, Protein from Homo sapiens)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kda subunit (50 kDa, Protein from Homo sapiens)
- (2z,6z,10z,14z,18z,22z,26z)-3,7,11,15,19,23,27,31-octamethyldotriaconta-2,6,10,14,18,22,26,30-octaen-1-yl dihydrogen phosphate (642 Da, Ligand)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4 (4 kDa, Protein from Homo sapiens)
- Transmembrane protein 258 (9 kDa, Protein from Homo sapiens)
- (4r,7r)-4-hydroxy-n,n,n-trimethyl-4,9-dioxo-7-[(undecanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphadocosan-1-aminium (636 Da, Ligand)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (68 kDa, Protein from Homo sapiens)
- Human oligosaccharyltransferase complex ost-b (Complex)
- Malectin (32 kDa, Protein from Homo sapiens)
- Peptide (588 Da, Protein from Homo sapiens)
- Human oligosaccharyltransferase complex (Complex from Homo sapiens)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit dad1 (12 kDa, Protein from Homo sapiens)
- Magnesium transporter protein 1 (Complex from Homo sapiens)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit stt3b (93 kDa, Protein from Homo sapiens)
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 6cfz
Q-score: 0.208
Science (2018) 360 pp. 552-558 [ DOI: doi:10.1126/science.aar6436 Pubmed: 29724956 ]
- Dash/dam1 complex (115 kDa, Complex from Chaetomium thermophilum)
- Hsk3 (6 kDa, Protein from Chaetomium thermophilum)
- Duo1 (12 kDa, Protein from Chaetomium thermophilum)
- Dad1,dad1 (10 kDa, Protein from Chaetomium thermophilum)
- Spc19 (17 kDa, Protein from Chaetomium thermophilum)
- Dam1 (6 kDa, Protein from Chaetomium thermophilum)
- Ask1 (8 kDa, Protein from Chaetomium thermophilum)
- Spc34 (27 kDa, Protein from Chaetomium thermophilum)
- Dad3 (7 kDa, Protein from Chaetomium thermophilum)
- Dad2 (10 kDa, Protein from Chaetomium thermophilum)
- Dad4 (8 kDa, Protein from Chaetomium thermophilum)
Resolution: 9.1 Å
EM Method: Subtomogram averaging
Fitted PDBs: 6ftg
Q-score: 0.126
Braunger K, Pfeffer S, Shrimal S, Gilmore R, Berninghausen O, Mandon EC, Becker T, Forster F, Beckmann R
Science (2018) 360 pp. 215-219 [ Pubmed: 29519914 DOI: doi:10.1126/science.aar7899 ]
- Ul13 (23 kDa, Protein from Rabbit)
- El40 (6 kDa, Protein from Rabbit)
- Ribosomal protein l11 (19 kDa, Protein from Rabbit)
- 5s ribosomal rna (38 kDa, RNA from Rabbit)
- Dad1 (8 kDa, Protein from Dog)
- El30 (10 kDa, Protein from Rabbit)
- 60s acidic ribosomal protein p0 (21 kDa, Protein from Rabbit)
- [(2~{s},3~{r},4~{r},5~{s},6~{r})-3-acetamido-6-(hydroxymethyl)-4,5-bis(oxidanyl)oxan-2-yl]methyl-[oxidanyl-[(2~{z},6~{z},10~{z})-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraenoxy]phosphoryl]oxy-phosphinic acid (651 Da, Ligand)
- Ribosomal protein l37 (10 kDa, Protein from Rabbit)
- Ribosomal protein l10 (predicted) (24 kDa, Protein from Rabbit)
- 80s ribosome from wt canine rough microsomal membranes bound to the endoplasmic reticulum protein translocon (Complex)
- Ribosomal protein l37a (10 kDa, Protein from Rabbit)
- El19 (21 kDa, Protein from Rabbit)
- El33 (12 kDa, Protein from Rabbit)
- El38 (8 kDa, Protein from Rabbit)
- El31 (12 kDa, Protein from Rabbit)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1,rpn1 (14 kDa, Protein from Dog)
- Ul6 (21 kDa, Protein from Rabbit)
- Magnesium ion (24 Da, Ligand)
- 60s ribosomal subunit (Complex from Oryctolagus cuniculus)
- Mammalian oligosaccharyltransferase (Complex from Canis lupus familiaris)
- Ribosomal protein l26 (15 kDa, Protein from Rabbit)
- Ul15 (16 kDa, Protein from Rabbit)
- El39 (6 kDa, Protein from Rabbit)
- 60s ribosomal protein l41 (3 kDa, Protein from Rabbit)
- Ribosomal protein l12 (17 kDa, Protein from Rabbit)
- Ul3 (45 kDa, Protein from Rabbit)
- 5.8s ribosomal rna (50 kDa, RNA from Rabbit)
- Ost48 (2 kDa, Protein from Dog)
- Ost4 (3 kDa, Protein from Dog)
- El21 (18 kDa, Protein from Rabbit)
- 60s ribosomal protein l27 (15 kDa, Protein from Rabbit)
- 28s ribosomal rna (1 MDa, RNA from Rabbit)
- Protein transport protein sec61 subunit beta (3 kDa, Protein from Dog)
- Ul14 (21 kDa, Protein from Rabbit)
- Protein transport protein sec61 subunit gamma (7 kDa, Protein from Dog)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit stt3a (80 kDa, Protein from Dog)
- Tmem258 (5 kDa, Protein from Dog)
- El32 (15 kDa, Protein from Rabbit)
- Zinc ion (65 Da, Ligand)
- Ul22 (17 kDa, Protein from Rabbit)
- Ribosomal protein l4 (41 kDa, Protein from Rabbit)
- El13 (24 kDa, Protein from Rabbit)
- Oligosaccharyltransferase complex subunit ostc (13 kDa, Protein from Dog)
- El28 (15 kDa, Protein from Rabbit)
- El20 (20 kDa, Protein from Rabbit)
- El22 (11 kDa, Protein from Rabbit)
- Rpn2 (6 kDa, Protein from Dog)
- El29 (14 kDa, Protein from Rabbit)
- Protein transport protein sec61 subunit alpha isoform 1 (50 kDa, Protein from Dog)
- Ribosomal protein l24 (7 kDa, Protein from Rabbit)
- 60s ribosomal protein l29 (8 kDa, Protein from Rabbit)
- El34 (12 kDa, Protein from Rabbit)
- 60s ribosomal protein l36 (11 kDa, Protein from Rabbit)
- Ribosomal protein l14 (16 kDa, Protein from Rabbit)
- Ul14 (13 kDa, Protein from Rabbit)
- 60s ribosomal protein l5 (34 kDa, Protein from Rabbit)
- Ul2 (26 kDa, Protein from Rabbit)
- Ribosomal protein l15 (24 kDa, Protein from Rabbit)
- Ul23 (13 kDa, Protein from Rabbit)
- El42 (12 kDa, Protein from Rabbit)
- Ul30 (26 kDa, Protein from Rabbit)
- Sec61 protein conducting channel (Complex from Canis lupus familiaris)
- 60s ribosomal protein l6 (28 kDa, Protein from Rabbit)
- El8 (27 kDa, Protein from Rabbit)
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 6fti
Q-score: 0.207
Braunger K, Pfeffer S, Shrimal S, Gilmore R, Berninghausen O, Mandon EC, Becker T, Forster F, Beckmann R
Science (2018) 360 pp. 215-219 [ Pubmed: 29519914 DOI: doi:10.1126/science.aar7899 ]
- Ul13 (23 kDa, Protein from Rabbit)
- El40 (6 kDa, Protein from Rabbit)
- P-site trna (24 kDa, RNA from Rabbit)
- Ribosomal protein l11 (19 kDa, Protein from Rabbit)
- 5s ribosomal rna (38 kDa, RNA from Rabbit)
- El30 (10 kDa, Protein from Rabbit)
- Tmem258 (4 kDa, Protein from Dog)
- 60s acidic ribosomal protein p0 (21 kDa, Protein from Rabbit)
- [(2~{s},3~{r},4~{r},5~{s},6~{r})-3-acetamido-6-(hydroxymethyl)-4,5-bis(oxidanyl)oxan-2-yl]methyl-[oxidanyl-[(2~{z},6~{z},10~{z})-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraenoxy]phosphoryl]oxy-phosphinic acid (651 Da, Ligand)
- Ribosomal protein l37 (10 kDa, Protein from Rabbit)
- Ribosomal protein l10 (predicted) (24 kDa, Protein from Rabbit)
- Ribosomal protein l37a (10 kDa, Protein from Rabbit)
- El19 (21 kDa, Protein from Rabbit)
- Mammalian oligosaccharyltransferase in complex with sec61 and the 80s ribosome (Complex)
- 60s ribosomal subunit (Complex from Oryctolagus cuniculus)
- El33 (12 kDa, Protein from Rabbit)
- El31 (12 kDa, Protein from Rabbit)
- El38 (8 kDa, Protein from Rabbit)
- Ul6 (21 kDa, Protein from Rabbit)
- Magnesium ion (24 Da, Ligand)
- 28s rrna (1 MDa, RNA from Rabbit)
- 60s ribosomal protein l41 (3 kDa, Protein from Rabbit)
- Ribosomal protein l26 (15 kDa, Protein from Rabbit)
- Ul15 (16 kDa, Protein from Rabbit)
- El39 (6 kDa, Protein from Rabbit)
- 5.8s ribosomal rna (50 kDa, RNA from Rabbit)
- Ribosomal protein l12 (17 kDa, Protein from Rabbit)
- Ul3 (45 kDa, Protein from Rabbit)
- Ost48 (2 kDa, Protein from Dog)
- El21 (18 kDa, Protein from Rabbit)
- 60s ribosomal protein l27 (15 kDa, Protein from Rabbit)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1,rpn1 (12 kDa, Protein from Dog)
- Ul29 (14 kDa, Protein from Rabbit)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4 (3 kDa, Protein from Dog)
- Protein transport protein sec61 subunit beta (3 kDa, Protein from Dog)
- Ul14 (21 kDa, Protein from Rabbit)
- Protein transport protein sec61 subunit gamma (7 kDa, Protein from Dog)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit stt3a (80 kDa, Protein from Dog)
- El32 (15 kDa, Protein from Rabbit)
- Zinc ion (65 Da, Ligand)
- Dad1 (9 kDa, Protein from Dog)
- Ul22 (17 kDa, Protein from Rabbit)
- Ribosomal protein l4 (41 kDa, Protein from Rabbit)
- Rpn1 (6 kDa, Protein from Dog)
- El13 (24 kDa, Protein from Rabbit)
- Oligosaccharyltransferase complex subunit ostc (13 kDa, Protein from Dog)
- El28 (15 kDa, Protein from Rabbit)
- El20 (20 kDa, Protein from Rabbit)
- El22 (11 kDa, Protein from Rabbit)
- Oligosaccharyltransferase (Complex from Canis lupus familiaris)
- Protein transport protein sec61 subunit alpha isoform 1 (50 kDa, Protein from Dog)
- Ribosomal protein l24 (7 kDa, Protein from Rabbit)
- 60s ribosomal protein l29 (8 kDa, Protein from Rabbit)
- El34 (12 kDa, Protein from Rabbit)
- 60s ribosomal protein l36 (11 kDa, Protein from Rabbit)
- Ribosomal protein l14 (16 kDa, Protein from Rabbit)
- Ul14 (13 kDa, Protein from Rabbit)
- 60s ribosomal protein l5 (34 kDa, Protein from Rabbit)
- Ul2 (26 kDa, Protein from Rabbit)
- Ribosomal protein l15 (24 kDa, Protein from Rabbit)
- Ul23 (13 kDa, Protein from Rabbit)
- El42 (12 kDa, Protein from Rabbit)
- Ul30 (26 kDa, Protein from Rabbit)
- Sec61 protein conducting channel (Complex from Canis lupus familiaris)
- Unidentified tm (2 kDa, Protein from Dog)
- 60s ribosomal protein l6 (28 kDa, Protein from Rabbit)
- El8 (27 kDa, Protein from Rabbit)
Resolution: 4.7 Å
EM Method: Single-particle
Fitted PDBs: 6ftj
Q-score: 0.174
Braunger K, Pfeffer S, Shrimal S, Gilmore R, Berninghausen O, Mandon EC, Becker T, Forster F, Beckmann R
Science (2018) 360 pp. 215-219 [ Pubmed: 29519914 DOI: doi:10.1126/science.aar7899 ]
- 60s ribosomal protein l27 (15 kDa, Protein from Oryctolagus cuniculus)
- 5s ribosomal rna (38 kDa, RNA from Oryctolagus cuniculus)
- 28s rrna (1 MDa, RNA from Oryctolagus cuniculus)
- Ribosomal protein l12 (17 kDa, Protein from Oryctolagus cuniculus)
- El13 (24 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l6 (28 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l29 (8 kDa, Protein from Oryctolagus cuniculus)
- El42 (12 kDa, Protein from Oryctolagus cuniculus)
- Ul29 (14 kDa, Protein from Oryctolagus cuniculus)
- Ost48 (2 kDa, Protein from Canis lupus familiaris)
- El20 (20 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l22 (11 kDa, Protein from Oryctolagus cuniculus)
- Mammalian oligosaccharyltransferase in complex with sec61 and the non-programmed 80s ribosome (Complex)
- [(2~{s},3~{r},4~{r},5~{s},6~{r})-3-acetamido-6-(hydroxymethyl)-4,5-bis(oxidanyl)oxan-2-yl]methyl-[oxidanyl-[(2~{z},6~{z},10~{z})-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraenoxy]phosphoryl]oxy-phosphinic acid (651 Da, Ligand)
- Ul22 (17 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l26 (15 kDa, Protein from Oryctolagus cuniculus)
- 5.8s ribosomal rna (50 kDa, RNA from Oryctolagus cuniculus)
- Protein transport protein sec61 subunit alpha isoform 1 (47 kDa, Protein from Canis lupus familiaris)
- Ribosomal protein l14 (16 kDa, Protein from Oryctolagus cuniculus)
- Dad1 (8 kDa, Protein from Canis lupus familiaris)
- 60s ribosomal subunit (Complex from Oryctolagus cuniculus)
- Ul30 (26 kDa, Protein from Oryctolagus cuniculus)
- Magnesium ion (24 Da, Ligand)
- El30 (10 kDa, Protein from Oryctolagus cuniculus)
- Ul14 (21 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l37a (10 kDa, Protein from Oryctolagus cuniculus)
- El38 (8 kDa, Protein from Oryctolagus cuniculus)
- Ul8 (27 kDa, Protein from Oryctolagus cuniculus)
- Protein transport protein sec61 subunit beta (3 kDa, Protein from Canis lupus familiaris)
- Rpn2 (6 kDa, Protein from Canis lupus familiaris)
- El39 (6 kDa, Protein from Oryctolagus cuniculus)
- El21 (18 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l24 (7 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l36 (11 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l4 (41 kDa, Protein from Oryctolagus cuniculus)
- El33 (12 kDa, Protein from Oryctolagus cuniculus)
- El31 (12 kDa, Protein from Oryctolagus cuniculus)
- El34 (12 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l5 (34 kDa, Protein from Oryctolagus cuniculus)
- Ost4 (3 kDa, Protein from Canis lupus familiaris)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit stt3a (79 kDa, Protein from Canis lupus familiaris)
- Ribosomal protein l15 (24 kDa, Protein from Oryctolagus cuniculus)
- El28 (15 kDa, Protein from Oryctolagus cuniculus)
- Oligosaccharyltransferase complex subunit ostc (13 kDa, Protein from Canis lupus familiaris)
- 60s acidic ribosomal protein p0 (21 kDa, Protein from Oryctolagus cuniculus)
- Zinc ion (65 Da, Ligand)
- Ul23 (13 kDa, Protein from Oryctolagus cuniculus)
- Tmem258 (5 kDa, Protein from Canis lupus familiaris)
- Ul3 (45 kDa, Protein from Oryctolagus cuniculus)
- Ul13 (23 kDa, Protein from Oryctolagus cuniculus)
- El32 (15 kDa, Protein from Oryctolagus cuniculus)
- Ul6 (21 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l41 (3 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l11 (19 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l10 (predicted) (24 kDa, Protein from Oryctolagus cuniculus)
- Ul14 (13 kDa, Protein from Oryctolagus cuniculus)
- El19 (21 kDa, Protein from Oryctolagus cuniculus)
- El40 (6 kDa, Protein from Oryctolagus cuniculus)
- Oligosaccharyltransferase (Complex from Canis lupus familiaris)
- Ul15 (16 kDa, Protein from Oryctolagus cuniculus)
- Protein transport protein sec61 subunit gamma (7 kDa, Protein from Canis lupus familiaris)
- Sec61 protein conducting channel (Complex from Canis lupus familiaris)
- Ribosomal protein l37 (10 kDa, Protein from Oryctolagus cuniculus)
- Ul2 (26 kDa, Protein from Oryctolagus cuniculus)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1,rpn1 (17 kDa, Protein from Canis lupus familiaris)