Fibriansah G, Ng TS, Lim XN, Tan AWK, Shi J, Crowe JE, Lok SM
To Be Published
- Membrane polyprotein (8 kDa, Protein from dengue virus type 2)
- Envelope protein (54 kDa, Protein from dengue virus type 2)
- Human antibody 2d22 fab light chain (12 kDa, Protein from Homo sapiens)
- Dengue serotype 2 strain d2y98p-pp1 n153q mutant (Complex from dengue virus type 2)
- Human antibody 2d22 fab (heavy and light chains) (Complex from Homo sapiens)
- Human antibody 2d22 fab heavy chain (13 kDa, Protein from Homo sapiens)
- Dengue virus serotype 2 strain y98p-pp1 n153q mutant in complex with human antibody 2d22 fab at 37 deg c (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Fibriansah G, Ng TS, Lim XN, Tan AWK, Shi J, Crowe JE, Lok SM
To Be Published
- Envelope protein (54 kDa, Protein from dengue virus type 2)
- Dengue virus serotype 2 strain y98p-pp1 n153q mutant in complex with human antibody c10 fab at 37 deg c (Complex)
- Dengue serotype 2 strain d2y98p-pp1 n153q mutant (Complex from dengue virus type 2)
- Human antibody c10 fab (light chain) (11 kDa, Protein from Homo sapiens)
- Human antibody c10 fab (heavy and light chains) (Complex from Homo sapiens)
- Membrane protein (8 kDa, Protein from dengue virus type 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Human antibody c10 fab (heavy chain) (14 kDa, Protein from Homo sapiens)
Cryo-EM structure of dengue virus serotype 2 strain D2Y98P-PP1 at 4 deg C
Fibriansah G, Ng TS, Lim XN, Tan AWK, Shi J, Crowe JE, Lok SM
To Be Published
- Membrane polyprotein (8 kDa, Protein from dengue virus type 2)
- Dengue virus serotype 2 strain d2y98p-pp1 at 4 deg c (Complex from dengue virus type 2)
- Envelope protein (54 kDa, Protein from dengue virus type 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Fibriansah G, Ng TS, Lim XN, Tan AWK, Shi J, Crowe JE, Lok SM
To Be Published
- Human antibody 2d22 fab (heavy and light chains) (Complex from Homo sapiens)
- Envelope protein (54 kDa, Protein from dengue virus type 2)
- Dengue serotype 2 strain d2y98p-pp1 (Complex from dengue virus type 2)
- Dengue virus serotype 2 strain d2y98p-pp1 in complex with human antibody 2d22 fab at 37 deg c (Complex)
- Human antibody 2d22 fab (heavy chain) (13 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Human antibody 2d22 fab (light chain) (12 kDa, Protein from Homo sapiens)
- Membrane polyprotein (8 kDa, Protein from dengue virus type 2)
Fibriansah G, Lim EXY, Marzinek JK, Ng TS, Tan JL, Huber RG, Lim XN, Chew VSY, Kostyuchenko VA, Shi J, Anand GS, Bond PJ, Crowe Jr JE, Lok SM
PLoS Pathog (2021) 17 pp. e1009331-e1009331 [ DOI: doi:10.1371/journal.ppat.1009331 Pubmed: 33621239 ]
- Dengue virus 2 (Complex from Homo sapiens)
- Anti-dengue virus human monoclonal antibody 1c19 fab light chain (Protein from Homo sapiens)
- Human antibody 1c19 fab (Complex)
- Dengue virus serotype 2 strain pvp94/07 envelope protein (Protein from Dengue virus 2)
- Anti-dengue virus human monoclonal antibody 1c19 fab heavy chain (Protein from Homo sapiens)
- Dengue virus serotype 2 strain pvp94/07 membrane protein (Protein from Dengue virus 2)
- Dengue virus serotype 2 strain pvp94/07 in complex with human antibody 1c19 fab (Complex from Dengue virus 2)
Fibriansah G, Lim EXY, Marzinek JK, Ng TS, Tan JL, Huber RG, Lim XN, Chew VSY, Kostyuchenko VA, Shi J, Anand GS, Bond PJ, Crowe Jr JE, Lok SM
PLoS Pathog (2021) 17 pp. e1009331-e1009331 [ DOI: doi:10.1371/journal.ppat.1009331 Pubmed: 33621239 ]
- Dengue virus 2 (Complex)
- Anti-dengue virus human monoclonal antibody 1c19 fab light chain (Protein from Homo sapiens)
- Human antibody 1c19 fab (Complex)
- Dengue virus serotype 2 strain pvp94/07 envelope protein (Protein from Dengue virus 2)
- Anti-dengue virus human monoclonal antibody 1c19 fab heavy chain (Protein from Homo sapiens)
- Dengue virus serotype 2 strain pvp94/07 membrane protein (Protein from Dengue virus 2)
- Dengue virus serotype 2 strain pvp94/07 in complex with human antibody 1c19 fab (Complex from Dengue virus 2)
Chimeric flavivirus between Binjari virus and Dengue virus serotype-2
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 7kv8
Q-score: 0.701
Hardy JM, Newton ND, Modhiran N, Scott CAP, Venugopal H, Vet LJ, Young PR, Hall RA, Hobson-Peters J, Coulibaly F, Watterson D
Nat Commun (2021) 12 pp. 3266-3266 [ DOI: doi:10.1038/s41467-021-22773-1 Pubmed: 34075032 ]
- Water (18 Da, Ligand)
- (2s,3r,4z)-3-hydroxy-2-[(9e)-octadec-9-enoylamino]octadec-4-en-1-yl dihydrogen phosphate (643 Da, Ligand)
- Envelope protein e (54 kDa, Protein from Dengue virus 2)
- M and e from dengue virus serotype-2 isolate et300 form a complex that assembles into anti-parallel dimers, (m-e)2, in the t=3 icosahedral particle. (Complex from Dengue virus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Binjari virus (11 MDa, Virus from Binjari virus)
- Matrix protein m (8 kDa, Protein from Dengue virus 2)
- [(2~{r})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{z})-octadec-9-enoate (717 Da, Ligand)
Cryo-EM structure of Dengue virus serotype 2 complexed with Fab SIgN-3C at pH 6.5
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 7bub
Q-score: 0.376
Zhang S, Loy T, Ng TS, Lim XN, Chew SV, Tan TY, Xu M, Kostyuchenko VA, Tukijan F, Shi J, Fink K, Lok SM
Cell Rep (2020) 31 pp. 107584-107584 [ DOI: doi:10.1016/j.celrep.2020.107584 Pubmed: 32348755 ]
- Dengue virus serotype2 e protein (54 kDa, Protein from Dengue virus 2)
- Sign-3c fab heavy chain (14 kDa, Protein from Homo sapiens)
- Complex of dengue virus serotype 2 with sign-3c fab (Complex from Homo sapiens)
- Dengue virus serotype 2 m protein (8 kDa, Protein from Dengue virus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sign-3c fab light chain (11 kDa, Protein from Homo sapiens)
- Dengue virus serotype 2 (Complex)
- Sign-3c fab (Complex from Dengue virus 2)
Cryo-EM structure of Dengue virus serotype 2 complexed with Fab SIgN-3C at pH 8.0
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 7bud
Q-score: 0.334
Zhang S, Loy T, Ng TS, Lim XN, Chew SV, Tan TY, Xu M, Kostyuchenko VA, Tukijan F, Shi J, Fink K, Lok SM
Cell Rep (2020) 31 pp. 107584-107584 [ DOI: doi:10.1016/j.celrep.2020.107584 Pubmed: 32348755 ]
- Sign-3c fab heavy chain (14 kDa, Protein from Homo sapiens)
- Complex of dengue virus serotype 2 with sign-3c fab (Complex from Homo sapiens)
- Dengue virus serotype 2 m protein (8 kDa, Protein from Dengue virus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sign-3c fab light chain (11 kDa, Protein from Homo sapiens)
- Dengue virus serotype 2 e protein (54 kDa, Protein from Dengue virus 2)
- Dengue virus serotype 2 (Complex)
- Sign-3c fab (Complex from Dengue virus 2)
Cryo-EM structure of Dengue virus serotype 2 complexed with Fab SIgN-3C at pH 5.0
Resolution: 7.8 Å
EM Method: Single-particle
Fitted PDBs: 7bue
Q-score: 0.129
Zhang S, Loy T, Ng TS, Lim XN, Chew SV, Tan TY, Xu M, Kostyuchenko VA, Tukijan F, Shi J, Fink K, Lok SM
Cell Rep (2020) 31 pp. 107584-107584 [ DOI: doi:10.1016/j.celrep.2020.107584 Pubmed: 32348755 ]
- Sign-3c fab heavy chain (14 kDa, Protein from Homo sapiens)
- Complex of dengue virus serotype 2 with sign-3c fab (Complex from Homo sapiens)
- Dengue serotype 2 e protein ectodomain (43 kDa, Protein from Dengue virus 2)
- Sign-3c fab light chain (11 kDa, Protein from Homo sapiens)
- Dengue virus serotype 2 (Complex)
- Sign-3c fab (Complex from Dengue virus 2)