Structure of human oligosaccharyltransferase OST-A complex bound to NGI-1
Resolution: 3.61 Å
EM Method: Single-particle
Fitted PDBs: 8pn9
Q-score: 0.474
Lampson BL, Ramirez AS, Baro M, He L, Hegde M, Koduri V, Pfaff JL, Hanna RE, Kowal J, Shirole NH, He Y, Doench JG, Contessa JN, Locher KP, Kaelin Jr WG
Cell (2024) 187 pp. 2209-2223.e16 [ DOI: doi:10.1016/j.cell.2024.03.022 Pubmed: 38670073 ]
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4 (4 kDa, Protein from Homo sapiens)
- Transmembrane protein 258 (9 kDa, Protein from Homo sapiens)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (69 kDa, Protein from Homo sapiens)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kda subunit (50 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- Oligosaccharyltransferase complex ost-a with bound ngi-1 inhibitor (Complex from Homo sapiens)
- (4r,7r)-4-hydroxy-n,n,n-trimethyl-4,9-dioxo-7-[(undecanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphadocosan-1-aminium (636 Da, Ligand)
- 5-(dimethylsulfamoyl)-~{n}-(5-methyl-1,3-thiazol-2-yl)-2-pyrrolidin-1-yl-benzamide (394 Da, Ligand)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit dad1 (12 kDa, Protein from Homo sapiens)
- (2~{s},3~{r},4~{r},5~{s},6~{s})-2-(hydroxymethyl)-6-[(1~{s},2~{r},3~{r},4~{r},5'~{s},6~{s},7~{r},8~{s},9~{r},12~{r},13~{r},15~{s},16~{s},18~{r})-5',7,9,13-tetramethyl-3,15-bis(oxidanyl)spiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosane-6,2'-oxane]-16-yl]oxy-oxane-3,4,5-triol (610 Da, Ligand)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit stt3a (80 kDa, Protein from Homo sapiens)
- Oligosaccharyltransferase complex subunit ostc (16 kDa, Protein from Homo sapiens)
- Manganese (ii) ion (54 Da, Ligand)
- (2e,6e,10e,14e,18e,22e,26e)-3,7,11,15,19,23,27,31-octamethyldotriaconta-2,6,10,14,18,22,26,30-octaenyl trihydrogen diphosphate (722 Da, Ligand)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (68 kDa, Protein from Homo sapiens)
Structure of yeast oligosaccharylransferase complex with lipid-linked oligosaccharide bound
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8agb
Q-score: 0.553
Ramirez AS, de Capitani M, Pesciullesi G, Kowal J, Bloch JS, Irobalieva RN, Reymond JL, Aebi M, Locher KP
Nat Commun (2022) 13 pp. 7296-7296 [ Pubmed: 36435935 DOI: doi:10.1038/s41467-022-35067-x ]
- Yeast ost complex with lipid-linked oligosaccharide bound (284 kDa, Complex from Saccharomyces cerevisiae)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit stt3 (81 kDa, Protein from Saccharomyces cerevisiae)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit ost4 (6 kDa, Protein from Saccharomyces cerevisiae)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit ost2 (14 kDa, Protein from Saccharomyces cerevisiae)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit swp1 (31 kDa, Protein from Saccharomyces cerevisiae)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (54 kDa, Protein from Saccharomyces cerevisiae)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit wbp1 (49 kDa, Protein from Saccharomyces cerevisiae)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3 (39 kDa, Protein from Saccharomyces cerevisiae)
- Phosphono [(3~{r},6~{e},10~{e})-3,7,11,15-tetramethylhexadeca-6,10,14-trienyl] hydrogen phosphate (452 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Manganese (ii) ion (54 Da, Ligand)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit ost5 (9 kDa, Protein from Saccharomyces cerevisiae)
- 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine (758 Da, Ligand)
- Phosphatidylethanolamine (734 Da, Ligand)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8agc
Q-score: 0.548
Ramirez AS, de Capitani M, Pesciullesi G, Kowal J, Bloch JS, Irobalieva RN, Reymond JL, Aebi M, Locher KP
Nat Commun (2022) 13 pp. 7296-7296 [ Pubmed: 36435935 DOI: doi:10.1038/s41467-022-35067-x ]
- Dolichyl-diphosphooligosaccharide--protein glycotransferase (81 kDa, Protein from Saccharomyces cerevisiae)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit ost2 (14 kDa, Protein from Saccharomyces cerevisiae)
- Yeast ost complex with lipid-linked oligosaccharide and non-acceptor peptide bound (284 kDa, Complex from Saccharomyces cerevisiae)
- Peptide (682 Da, Protein from Saccharomyces cerevisiae)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (54 kDa, Protein from Saccharomyces cerevisiae)
- 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine (758 Da, Ligand)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit wbp1 (49 kDa, Protein from Saccharomyces cerevisiae)
- Ost4 isoform 1 (6 kDa, Protein from Saccharomyces cerevisiae)
- Ost3 isoform 1 (39 kDa, Protein from Saccharomyces cerevisiae)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (31 kDa, Protein from Saccharomyces cerevisiae)
- Manganese (ii) ion (54 Da, Ligand)
- 2-[3,6-bis(dimethylamino)xanthen-9-yl]-5-methanoyl-benzoate (414 Da, Ligand)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit ost5 (9 kDa, Protein from Saccharomyces cerevisiae)
- Phosphono [(3~{r},6~{e},10~{e})-3,7,11,15-tetramethylhexadeca-6,10,14-trienyl] hydrogen phosphate (452 Da, Ligand)
- Phosphatidylethanolamine (734 Da, Ligand)
Structure of yeast oligosaccharylransferase complex with acceptor peptide bound
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8age
Q-score: 0.571
Ramirez AS, de Capitani M, Pesciullesi G, Kowal J, Bloch JS, Irobalieva RN, Reymond JL, Aebi M, Locher KP
Nat Commun (2022) 13 pp. 7296-7296 [ Pubmed: 36435935 DOI: doi:10.1038/s41467-022-35067-x ]
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit stt3 (81 kDa, Protein from Saccharomyces cerevisiae)
- Water (18 Da, Ligand)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit ost2 (14 kDa, Protein from Saccharomyces cerevisiae)
- Yeast ost complex with acceptor peptide bound (284 kDa, Complex from Saccharomyces cerevisiae)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (54 kDa, Protein from Saccharomyces cerevisiae)
- 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine (758 Da, Ligand)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit wbp1 (49 kDa, Protein from Saccharomyces cerevisiae)
- Ost4 isoform 1 (6 kDa, Protein from Saccharomyces cerevisiae)
- Ost3 isoform 1 (39 kDa, Protein from Saccharomyces cerevisiae)
- (2~{s},3~{r},4~{r},5~{s},6~{s})-2-(hydroxymethyl)-6-[(1~{s},2~{r},3~{r},4~{r},5'~{s},6~{s},7~{r},8~{s},9~{r},12~{r},13~{r},15~{s},16~{s},18~{r})-5',7,9,13-tetramethyl-3,15-bis(oxidanyl)spiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosane-6,2'-oxane]-16-yl]oxy-oxane-3,4,5-triol (610 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (31 kDa, Protein from Saccharomyces cerevisiae)
- Manganese (ii) ion (54 Da, Ligand)
- 2-[3,6-bis(dimethylamino)xanthen-9-yl]-5-methanoyl-benzoate (414 Da, Ligand)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit ost5 (9 kDa, Protein from Saccharomyces cerevisiae)
- Peptide (696 Da, Protein from Saccharomyces cerevisiae)
- Phosphatidylethanolamine (734 Da, Ligand)
Subtomogram average of the human Sec61-TRAP-OSTA-translocon
Resolution: 7.6 Å
EM Method: Subtomogram averaging
Fitted PDBs: 8b6l
Q-score: 0.133
Gemmer M, Chaillet ML, van Loenhout J, Cuevas Arenas R, Vismpas D, Grollers-Mulderij M, Koh FA, Albanese P, Scheltema RA, Howes SC, Kotecha A, Fedry J, Forster F
Nature (2023) 614 pp. 160-167 [ DOI: doi:10.1038/s41586-022-05638-5 Pubmed: 36697828 ]
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4 (4 kDa, Protein from Homo sapiens)
- Transmembrane protein 258 (9 kDa, Protein from Homo sapiens)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (69 kDa, Protein from Homo sapiens)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit stt3a (80 kDa, Protein from Homo sapiens)
- Protein transport protein sec61 subunit beta (9 kDa, Protein from Homo sapiens)
- Protein transport protein sec61 subunit alpha isoform 1 (52 kDa, Protein from Homo sapiens)
- Translocon-associated protein subunit beta (20 kDa, Protein from Homo sapiens)
- Signal peptide mix (1 kDa, Protein from Homo sapiens)
- Translocon-associated protein subunit gamma (21 kDa, Protein from Homo sapiens)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit dad1 (12 kDa, Protein from Homo sapiens)
- Translocon-associated protein subunit alpha (32 kDa, Protein from Homo sapiens)
- Protein transport protein sec61 subunit gamma (7 kDa, Protein from Homo sapiens)
- Translocon-associated protein subunit delta (19 kDa, Protein from Homo sapiens)
- Oligosaccharyltransferase complex subunit ostc (16 kDa, Protein from Homo sapiens)
- Sec61-trap-osta translocon complex (Cellular component from Homo sapiens)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kda subunit (50 kDa, Protein from Homo sapiens)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (68 kDa, Protein from Homo sapiens)
Cryo-EM structure of yeast Ost6p containing oligosaccharyltransferase complex
Resolution: 3.46 Å
EM Method: Single-particle
Fitted PDBs: 7oci
Q-score: 0.514
Neuhaus JD, Wild R, Eyring J, Irobalieva RN, Kowal J, Lin CW, Locher KP, Aebi M
Glycobiology (2021) 31 pp. 1604-1615 [ Pubmed: 34974622 DOI: doi:10.1093/glycob/cwab084 ]
- Ost6p containing yeast oligosaccharyltransferase complex (Complex from Saccharomyces cerevisiae S288C)
- Dolichylphosphate (847 Da, Ligand)
- Digitonin (1 kDa, Ligand)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit ost4 (3 kDa, Protein from Saccharomyces cerevisiae S288C)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit ost5 (9 kDa, Protein from Saccharomyces cerevisiae S288C)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit ost6 - tm1 (2 kDa, Protein from Saccharomyces cerevisiae S288C)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit ost6 (37 kDa, Protein from Saccharomyces cerevisiae S288C)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit wbp1 (49 kDa, Protein from Saccharomyces cerevisiae S288C)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit swp1 (31 kDa, Protein from Saccharomyces cerevisiae S288C)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (54 kDa, Protein from Saccharomyces cerevisiae S288C)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit stt3 (81 kDa, Protein from Saccharomyces cerevisiae S288C)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit ost2 (14 kDa, Protein from Saccharomyces cerevisiae S288C)
Cryo-EM structure of human oligosaccharyltransferase complex OST-A
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 6s7o
Q-score: 0.485
Ramirez AS, Kowal J, Locher KP
Science (2019) 366 pp. 1372-1375 [ Pubmed: 31831667 DOI: doi:10.1126/science.aaz3505 ]
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4 (4 kDa, Protein from Homo sapiens)
- Transmembrane protein 258 (9 kDa, Protein from Homo sapiens)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (69 kDa, Protein from Homo sapiens)
- Human oligosaccharyltransferase complex (Complex from Homo sapiens)
- (4r,7r)-4-hydroxy-n,n,n-trimethyl-4,9-dioxo-7-[(undecanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphadocosan-1-aminium (636 Da, Ligand)
- Human oligosaccharyltransferase complex ost-a (Complex)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit dad1 (12 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kda subunit (50 kDa, Protein from Homo sapiens)
- Oligosaccharyltransferase complex subunit ostc (Complex from Homo sapiens)
- [(3~{r},6~{z},10~{z},14~{z},18~{z})-3,7,11,15,19,23-hexamethyltetracosa-6,10,14,18,22-pentaenyl] dihydrogen phosphate (508 Da, Ligand)
- (2~{s},3~{r},4~{r},5~{s},6~{s})-2-(hydroxymethyl)-6-[(1~{s},2~{r},3~{r},4~{r},5'~{s},6~{s},7~{r},8~{s},9~{r},12~{r},13~{r},15~{s},16~{s},18~{r})-5',7,9,13-tetramethyl-3,15-bis(oxidanyl)spiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosane-6,2'-oxane]-16-yl]oxy-oxane-3,4,5-triol (610 Da, Ligand)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit stt3a (80 kDa, Protein from Homo sapiens)
- Oligosaccharyltransferase complex subunit ostc (16 kDa, Protein from Homo sapiens)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (68 kDa, Protein from Homo sapiens)
Cryo-EM structure of human oligosaccharyltransferase complex OST-B
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 6s7t
Q-score: 0.509
Ramirez AS, Kowal J, Locher KP
Science (2019) 366 pp. 1372-1375 [ Pubmed: 31831667 DOI: doi:10.1126/science.aaz3505 ]
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4 (4 kDa, Protein from Homo sapiens)
- Transmembrane protein 258 (9 kDa, Protein from Homo sapiens)
- Human oligosaccharyltransferase complex ost-b (Complex)
- Human oligosaccharyltransferase complex (Complex from Homo sapiens)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (69 kDa, Protein from Homo sapiens)
- Magnesium transporter protein 1 (38 kDa, Protein from Homo sapiens)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit stt3b (93 kDa, Protein from Homo sapiens)
- Magnesium transporter protein 1 (Complex from Homo sapiens)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit dad1 (12 kDa, Protein from Homo sapiens)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kda subunit (50 kDa, Protein from Homo sapiens)
- Peptide (588 Da, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- (2~{s},3~{r},4~{r},5~{s},6~{s})-2-(hydroxymethyl)-6-[(1~{s},2~{r},3~{r},4~{r},5'~{s},6~{s},7~{r},8~{s},9~{r},12~{r},13~{r},15~{s},16~{s},18~{r})-5',7,9,13-tetramethyl-3,15-bis(oxidanyl)spiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosane-6,2'-oxane]-16-yl]oxy-oxane-3,4,5-triol (610 Da, Ligand)
- Malectin (32 kDa, Protein from Homo sapiens)
- (4r,7r)-4-hydroxy-n,n,n-trimethyl-4,9-dioxo-7-[(undecanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphadocosan-1-aminium (636 Da, Ligand)
- (2z,6z,10z,14z,18z,22z,26z)-3,7,11,15,19,23,27,31-octamethyldotriaconta-2,6,10,14,18,22,26,30-octaen-1-yl dihydrogen phosphate (642 Da, Ligand)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (68 kDa, Protein from Homo sapiens)
Resolution: 9.1 Å
EM Method: Subtomogram averaging
Fitted PDBs: 6ftg
Q-score: 0.126
Braunger K, Pfeffer S, Shrimal S, Gilmore R, Berninghausen O, Mandon EC, Becker T, Forster F, Beckmann R
Science (2018) 360 pp. 215-219 [ DOI: doi:10.1126/science.aar7899 Pubmed: 29519914 ]
- Ost4 (3 kDa, Protein from Dog)
- Ribosomal protein l37a (10 kDa, Protein from Rabbit)
- Sec61 protein conducting channel (Complex from Canis lupus familiaris)
- El13 (24 kDa, Protein from Rabbit)
- Ribosomal protein l12 (17 kDa, Protein from Rabbit)
- 60s ribosomal protein l36 (11 kDa, Protein from Rabbit)
- Mammalian oligosaccharyltransferase (Complex from Canis lupus familiaris)
- El8 (27 kDa, Protein from Rabbit)
- El34 (12 kDa, Protein from Rabbit)
- 60s ribosomal subunit (Complex from Oryctolagus cuniculus)
- El20 (20 kDa, Protein from Rabbit)
- El19 (21 kDa, Protein from Rabbit)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit stt3a (80 kDa, Protein from Dog)
- Ost48 (2 kDa, Protein from Dog)
- 60s ribosomal protein l5 (34 kDa, Protein from Rabbit)
- 60s ribosomal protein l27 (15 kDa, Protein from Rabbit)
- El22 (11 kDa, Protein from Rabbit)
- 60s ribosomal protein l41 (3 kDa, Protein from Rabbit)
- Zinc ion (65 Da, Ligand)
- Ul22 (17 kDa, Protein from Rabbit)
- Ul6 (21 kDa, Protein from Rabbit)
- El33 (12 kDa, Protein from Rabbit)
- Ribosomal protein l15 (24 kDa, Protein from Rabbit)
- El21 (18 kDa, Protein from Rabbit)
- Ribosomal protein l24 (7 kDa, Protein from Rabbit)
- 60s acidic ribosomal protein p0 (21 kDa, Protein from Rabbit)
- 5s ribosomal rna (38 kDa, RNA from Rabbit)
- Tmem258 (5 kDa, Protein from Dog)
- Protein transport protein sec61 subunit gamma (7 kDa, Protein from Dog)
- El32 (15 kDa, Protein from Rabbit)
- Ul30 (26 kDa, Protein from Rabbit)
- Dad1 (8 kDa, Protein from Dog)
- Rpn2 (6 kDa, Protein from Dog)
- Ribosomal protein l4 (41 kDa, Protein from Rabbit)
- Protein transport protein sec61 subunit alpha isoform 1 (50 kDa, Protein from Dog)
- Ul13 (23 kDa, Protein from Rabbit)
- El38 (8 kDa, Protein from Rabbit)
- El39 (6 kDa, Protein from Rabbit)
- El40 (6 kDa, Protein from Rabbit)
- Protein transport protein sec61 subunit beta (3 kDa, Protein from Dog)
- Ribosomal protein l10 (predicted) (24 kDa, Protein from Rabbit)
- Ul15 (16 kDa, Protein from Rabbit)
- Ribosomal protein l11 (19 kDa, Protein from Rabbit)
- El31 (12 kDa, Protein from Rabbit)
- Ul14 (13 kDa, Protein from Rabbit)
- Ribosomal protein l37 (10 kDa, Protein from Rabbit)
- Ul2 (26 kDa, Protein from Rabbit)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1,rpn1 (14 kDa, Protein from Dog)
- Ul3 (45 kDa, Protein from Rabbit)
- 5.8s ribosomal rna (50 kDa, RNA from Rabbit)
- 80s ribosome from wt canine rough microsomal membranes bound to the endoplasmic reticulum protein translocon (Complex)
- 60s ribosomal protein l29 (8 kDa, Protein from Rabbit)
- Ribosomal protein l26 (15 kDa, Protein from Rabbit)
- Magnesium ion (24 Da, Ligand)
- 60s ribosomal protein l6 (28 kDa, Protein from Rabbit)
- Ul14 (21 kDa, Protein from Rabbit)
- El28 (15 kDa, Protein from Rabbit)
- Ul23 (13 kDa, Protein from Rabbit)
- Oligosaccharyltransferase complex subunit ostc (13 kDa, Protein from Dog)
- El30 (10 kDa, Protein from Rabbit)
- Ribosomal protein l14 (16 kDa, Protein from Rabbit)
- 28s ribosomal rna (1 MDa, RNA from Rabbit)
- El29 (14 kDa, Protein from Rabbit)
- El42 (12 kDa, Protein from Rabbit)
- [(2~{s},3~{r},4~{r},5~{s},6~{r})-3-acetamido-6-(hydroxymethyl)-4,5-bis(oxidanyl)oxan-2-yl]methyl-[oxidanyl-[(2~{z},6~{z},10~{z})-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraenoxy]phosphoryl]oxy-phosphinic acid (651 Da, Ligand)
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 6fti
Q-score: 0.207
Braunger K, Pfeffer S, Shrimal S, Gilmore R, Berninghausen O, Mandon EC, Becker T, Forster F, Beckmann R
Science (2018) 360 pp. 215-219 [ DOI: doi:10.1126/science.aar7899 Pubmed: 29519914 ]
- P-site trna (24 kDa, RNA from Rabbit)
- Ribosomal protein l37a (10 kDa, Protein from Rabbit)
- Sec61 protein conducting channel (Complex from Canis lupus familiaris)
- El13 (24 kDa, Protein from Rabbit)
- Ribosomal protein l12 (17 kDa, Protein from Rabbit)
- 60s ribosomal protein l36 (11 kDa, Protein from Rabbit)
- El8 (27 kDa, Protein from Rabbit)
- El34 (12 kDa, Protein from Rabbit)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1,rpn1 (12 kDa, Protein from Dog)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit stt3a (80 kDa, Protein from Dog)
- Oligosaccharyltransferase (Complex from Canis lupus familiaris)
- El19 (21 kDa, Protein from Rabbit)
- El20 (20 kDa, Protein from Rabbit)
- Ost48 (2 kDa, Protein from Dog)
- 60s ribosomal protein l5 (34 kDa, Protein from Rabbit)
- 60s ribosomal protein l27 (15 kDa, Protein from Rabbit)
- El22 (11 kDa, Protein from Rabbit)
- 60s ribosomal protein l41 (3 kDa, Protein from Rabbit)
- Zinc ion (65 Da, Ligand)
- Ul22 (17 kDa, Protein from Rabbit)
- Ul6 (21 kDa, Protein from Rabbit)
- El33 (12 kDa, Protein from Rabbit)
- Ribosomal protein l15 (24 kDa, Protein from Rabbit)
- El21 (18 kDa, Protein from Rabbit)
- Ul29 (14 kDa, Protein from Rabbit)
- Ribosomal protein l24 (7 kDa, Protein from Rabbit)
- 60s acidic ribosomal protein p0 (21 kDa, Protein from Rabbit)
- 5s ribosomal rna (38 kDa, RNA from Rabbit)
- Protein transport protein sec61 subunit gamma (7 kDa, Protein from Dog)
- El32 (15 kDa, Protein from Rabbit)
- Ul30 (26 kDa, Protein from Rabbit)
- Mammalian oligosaccharyltransferase in complex with sec61 and the 80s ribosome (Complex)
- Unidentified tm (2 kDa, Protein from Dog)
- Ribosomal protein l4 (41 kDa, Protein from Rabbit)
- Protein transport protein sec61 subunit alpha isoform 1 (50 kDa, Protein from Dog)
- Ul13 (23 kDa, Protein from Rabbit)
- El38 (8 kDa, Protein from Rabbit)
- El39 (6 kDa, Protein from Rabbit)
- El40 (6 kDa, Protein from Rabbit)
- Protein transport protein sec61 subunit beta (3 kDa, Protein from Dog)
- Ribosomal protein l10 (predicted) (24 kDa, Protein from Rabbit)
- Tmem258 (4 kDa, Protein from Dog)
- Ul15 (16 kDa, Protein from Rabbit)
- Ribosomal protein l11 (19 kDa, Protein from Rabbit)
- El31 (12 kDa, Protein from Rabbit)
- 60s ribosomal subunit (Complex from Oryctolagus cuniculus)
- Ul14 (13 kDa, Protein from Rabbit)
- Ribosomal protein l37 (10 kDa, Protein from Rabbit)
- Ul2 (26 kDa, Protein from Rabbit)
- Dad1 (9 kDa, Protein from Dog)
- Ul3 (45 kDa, Protein from Rabbit)
- 5.8s ribosomal rna (50 kDa, RNA from Rabbit)
- 60s ribosomal protein l29 (8 kDa, Protein from Rabbit)
- Ribosomal protein l26 (15 kDa, Protein from Rabbit)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4 (3 kDa, Protein from Dog)
- Magnesium ion (24 Da, Ligand)
- 60s ribosomal protein l6 (28 kDa, Protein from Rabbit)
- Ul14 (21 kDa, Protein from Rabbit)
- El28 (15 kDa, Protein from Rabbit)
- 28s rrna (1 MDa, RNA from Rabbit)
- Ul23 (13 kDa, Protein from Rabbit)
- Oligosaccharyltransferase complex subunit ostc (13 kDa, Protein from Dog)
- El30 (10 kDa, Protein from Rabbit)
- Ribosomal protein l14 (16 kDa, Protein from Rabbit)
- Rpn1 (6 kDa, Protein from Dog)
- El42 (12 kDa, Protein from Rabbit)
- [(2~{s},3~{r},4~{r},5~{s},6~{r})-3-acetamido-6-(hydroxymethyl)-4,5-bis(oxidanyl)oxan-2-yl]methyl-[oxidanyl-[(2~{z},6~{z},10~{z})-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraenoxy]phosphoryl]oxy-phosphinic acid (651 Da, Ligand)