Cryo-EM structure of two dynein tail domains bound to dynactin and BICDR1
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 6f1t
Q-score: 0.269
Urnavicius L, Lau CK, Elshenawy MM, Morales-Rios E, Motz C, Yildiz A, Carter AP
Nature (2018) 554 pp. 202-206 [ Pubmed: 29420470 DOI: doi:10.1038/nature25462 ]
- Arp1 actin related protein 1 homolog a (42 kDa, Protein from Sus scrofa)
- Capping protein (actin filament) muscle z-line, alpha 1 (33 kDa, Protein from Sus scrofa)
- Cytoplasmic dynein 1 light intermediate chain 2 (54 kDa, Protein from Homo sapiens)
- Dynactin 6 (20 kDa, Protein from Sus scrofa)
- Dynactin subunit 4 (22 kDa, Protein from Sus scrofa)
- Dynactin subunit 2 (52 kDa, Protein from Sus scrofa)
- Bicd family-like cargo adapter 1 (Complex from Mus musculus)
- Dynactin (Complex from Sus scrofa)
- Dynactin subunit 2 (7 kDa, Protein from Sus scrofa)
- F-actin capping protein beta subunit (30 kDa, Protein from Sus scrofa)
- Dynactin subunit 3 (5 kDa, Protein from Sus scrofa)
- Cytoplasmic dynein 1 intermediate chain 2 (68 kDa, Protein from Homo sapiens)
- Dynactin subunit 1 (4 kDa, Protein from Sus scrofa)
- Dynactin subunit 2 (7 kDa, Protein from Sus scrofa)
- Dynactin subunit 2 (5 kDa, Protein from Sus scrofa)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Dynein light chain roadblock-type 1 (10 kDa, Protein from Homo sapiens)
- Dynactin subunit 2 (50 kDa, Protein from Sus scrofa)
- Dynactin subunit 5 (20 kDa, Protein from Sus scrofa)
- Dynactin subunit 1 (4 kDa, Protein from Sus scrofa)
- Actin, cytoplasmic 1 (41 kDa, Protein from Sus scrofa)
- Cryo-em map of two dynein tail domains bound to dynactin and bicdr1 (Complex)
- Bicd family-like cargo adapter 1,bicd family-like cargo adapter 1,bicd family-like cargo adapter 1 (42 kDa, Protein from Mus musculus)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Dynactin subunit 2 (2 kDa, Protein from Sus scrofa)
- Dynein (Complex from Homo sapiens)
- Actin related protein 10 homolog (43 kDa, Protein from Sus scrofa)
- Bicd family-like cargo adapter 1,bicd family-like cargo adapter 1,bicd family-like cargo adapter 1,bicdr-1 (42 kDa, Protein from Mus musculus)
- Cytoplasmic dynein 1 heavy chain 1,cytoplasmic dynein 1 heavy chain 1,cytoplasmic dynein 1 heavy chain 1,dynein heavy chain,cytoplasmic dynein 1 heavy chain 1,cytoplasmic dynein 1 heavy chain 1,cytoplasmic dynein 1 heavy chain 1,cytoplasmic dynein 1 heavy chain 1,dynein heavy chain,cytoplasmic dynein 1 heavy chain 1,cytoplasmic dynein 1 heavy chain 1 (119 kDa, Protein from Homo sapiens)
- Dynactin subunit 2 (10 kDa, Protein from Sus scrofa)
Cryo-EM structure of two dynein tail domains bound to dynactin and HOOK3
Resolution: 6.7 Å
EM Method: Single-particle
Fitted PDBs: 6f38
Q-score: 0.23
Urnavicius L, Lau CK, Elshenawy MM, Morales-Rios E, Motz C, Yildiz A, Carter AP
Nature (2018) 554 pp. 202-206 [ Pubmed: 29420470 DOI: doi:10.1038/nature25462 ]
- Arp1 actin related protein 1 homolog a (42 kDa, Protein from Sus scrofa)
- Dynactin subunit 2 (3 kDa, Protein from Sus scrofa)
- Complex of two dynein tail domains bound to dynactin and hook3 (Complex)
- Capping protein (actin filament) muscle z-line, alpha 1 (33 kDa, Protein from Sus scrofa)
- Dynactin subunit 2 (10 kDa, Protein from Sus scrofa)
- Cytoplasmic dynein 1 light intermediate chain 2 (54 kDa, Protein from Homo sapiens)
- Dynactin 6 (20 kDa, Protein from Sus scrofa)
- Dynactin subunit 2 (49 kDa, Protein from Sus scrofa)
- Dynactin subunit 4 (22 kDa, Protein from Sus scrofa)
- Dynactin (Complex from Sus scrofa)
- Hook3 (18 kDa, Protein from Homo sapiens)
- Dynactin subunit 2 (7 kDa, Protein from Sus scrofa)
- F-actin capping protein beta subunit (30 kDa, Protein from Sus scrofa)
- Hook3 (Complex from Homo sapiens)
- Dynactin subunit 3 (5 kDa, Protein from Sus scrofa)
- Dynactin subunit 2 (7 kDa, Protein from Sus scrofa)
- Cytoplasmic dynein 1 intermediate chain 2 (68 kDa, Protein from Homo sapiens)
- Dynactin subunit 1 (4 kDa, Protein from Sus scrofa)
- Dynactin subunit 2 (5 kDa, Protein from Sus scrofa)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Dynein light chain roadblock-type 1 (10 kDa, Protein from Homo sapiens)
- Dynactin subunit 1 (4 kDa, Protein from Sus scrofa)
- Dynactin subunit 5 (20 kDa, Protein from Sus scrofa)
- Actin, cytoplasmic 1 (41 kDa, Protein from Sus scrofa)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Dynein (Complex from Homo sapiens)
- Actin related protein 10 homolog (43 kDa, Protein from Sus scrofa)
- Cytoplasmic dynein 1 heavy chain 1 (168 kDa, Protein from Homo sapiens)
- Dynactin subunit 2 (52 kDa, Protein from Sus scrofa)
CryoEM structure of dynactin complex with p150-glued projection
Urnavicius L, Zhang K, Diamant AG, Motz C, Schlager MA, Yu M, Patel NA, Robinson CV, Carter AP
Science (2015) 347 pp. 1441-1446 [ Pubmed: 25814576 DOI: doi:10.1126/science.aaa4080 ]
- Dynactin subunit 1 (150 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 2 (50 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 5 (25 kDa, Protein from Sus scrofa domesticus)
- Actin related protein 1 (42 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 6 (27 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 4 (62 kDa, Protein from Sus scrofa domesticus)
- Actin related protein 11 (46 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 3 (22 kDa, Protein from Sus scrofa domesticus)
- Actin capping protein (33 kDa, Protein from Sus scrofa domesticus)
- Beta-actin (43 kDa, Protein from Sus scrofa domesticus)
- Dynactin complex from pig brain (1 MDa, Sample)
CryoEM structure of dynactin complex at 4.1 angstrom resolution
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 5adx
Q-score: 0.301
Urnavicius L, Zhang K, Diamant AG, Motz C, Schlager MA, Yu M, Patel NA, Robinson CV, Carter AP
Science (2015) 347 pp. 1441-1446 [ Pubmed: 25814576 DOI: doi:10.1126/science.aaa4080 ]
- Dynactin subunit 1 (150 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 2 (50 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 5 (25 kDa, Protein from Sus scrofa domesticus)
- Actin related protein 1 (42 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 6 (27 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 4 (62 kDa, Protein from Sus scrofa domesticus)
- Actin related protein 11 (46 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 3 (22 kDa, Protein from Sus scrofa domesticus)
- Actin capping protein (33 kDa, Protein from Sus scrofa domesticus)
- Beta-actin (43 kDa, Protein from Sus scrofa domesticus)
- Dynactin complex from pig brain (1 MDa, Sample)
CryoEM reconstruction of dynactin complex from pig brain at 4.0 Angstrom resolution overall
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 5adx
Q-score: 0.229
Urnavicius L, Zhang K, Diamant AG, Motz C, Schlager MA, Yu M, Patel NA, Robinson CV, Carter AP
Science (2015) 347 pp. 1441-1446 [ Pubmed: 25814576 DOI: doi:10.1126/science.aaa4080 ]
- Dynactin subunit 1 (150 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 2 (50 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 5 (25 kDa, Protein from Sus scrofa domesticus)
- Actin related protein 1 (42 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 6 (27 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 4 (62 kDa, Protein from Sus scrofa domesticus)
- Actin related protein 11 (46 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 3 (22 kDa, Protein from Sus scrofa domesticus)
- Actin capping protein (33 kDa, Protein from Sus scrofa domesticus)
- Beta-actin (43 kDa, Protein from Sus scrofa domesticus)
- Dynactin complex from pig brain (1 MDa, Sample)