Structure of outer-arm dyneins bound to microtubule with microtubule binding state 1(MTBS-1)
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7k58
Q-score: 0.357
Rao Q, Han L, Wang Y, Chai P, Kuo YW, Yang R, Hu F, Yang Y, Howard J, Zhang K
Nat Struct Mol Biol (2021) 28 pp. 799-810 [ Pubmed: 34556869 DOI: doi:10.1038/s41594-021-00656-9 ]
- Dynein light chain roadblock (10 kDa, Protein from Tetrahymena thermophila)
- Outer-arm dynein (2 MDa, Complex from Tetrahymena thermophila)
- Dynein light chain tctex-type 1 protein (12 kDa, Protein from Tetrahymena thermophila)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Dynein light chain (11 kDa, Protein from Tetrahymena thermophila)
- Dynein light chain (10 kDa, Protein from Tetrahymena thermophila)
- Dynein light chain roadblock-type 2 protein (12 kDa, Protein from Tetrahymena thermophila)
- Dynein light chain (11 kDa, Protein from Tetrahymena thermophila)
- Dynein light chain (11 kDa, Protein from Tetrahymena thermophila)
- Magnesium ion (24 Da, Ligand)
- Gamma heavy chain (450 kDa, Protein from Tetrahymena thermophila)
- Thioredoxin (12 kDa, Protein from Tetrahymena thermophila)
- Dynein light chain (10 kDa, Protein from Tetrahymena thermophila)
- Dynein heavy chain, outer arm protein (533 kDa, Protein from Tetrahymena thermophila)
- Dynein intermediate chain 2 (69 kDa, Protein from Tetrahymena thermophila)
- Dynein light chain 1 (21 kDa, Protein from Tetrahymena thermophila)
- Dynein light chain (10 kDa, Protein from Tetrahymena thermophila)
- Dynein light chain 2a (14 kDa, Protein from Tetrahymena thermophila)
- Flagellar outer dynein arm intermediate protein, putative (63 kDa, Protein from Tetrahymena thermophila)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Outer arm dynein beta heavy chain (529 kDa, Protein from Tetrahymena thermophila)
Structure of outer-arm dynein bound to microtubule doublet in microtubule binding state 2 (MTBS-2)
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 7k5b
Q-score: 0.264
Rao Q, Han L, Wang Y, Chai P, Kuo YW, Yang R, Hu F, Yang Y, Howard J, Zhang K
Nat Struct Mol Biol (2021) 28 pp. 799-810 [ Pubmed: 34556869 DOI: doi:10.1038/s41594-021-00656-9 ]
- Dynein light chain (11 kDa, Protein from Tetrahymena thermophila)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Dynein light chain (11 kDa, Protein from Tetrahymena thermophila)
- Dynein light chain (12 kDa, Protein from Tetrahymena thermophila)
- Dynein light chain (10 kDa, Protein from Tetrahymena thermophila)
- Dynein heavy chain, outer arm protein (533 kDa, Protein from Tetrahymena thermophila)
- Dynein light chain 4a (16 kDa, Protein from Tetrahymena thermophila)
- Dynein light chain 1 (21 kDa, Protein from Tetrahymena thermophila)
- Dynein light chain roadblock-type 2 protein (17 kDa, Protein from Tetrahymena thermophila)
- Dynein light chain roadblock-type 2 protein (14 kDa, Protein from Tetrahymena thermophila)
- Magnesium ion (24 Da, Ligand)
- Thioredoxin (12 kDa, Protein from Tetrahymena thermophila)
- Outer arm dynein beta heavy chain (529 kDa, Protein from Tetrahymena thermophila)
- Dynein light chain (10 kDa, Protein from Tetrahymena thermophila)
- Dynein light chain tctex-type 1 protein (12 kDa, Protein from Tetrahymena thermophila)
- Dynein intermediate chain 2 (69 kDa, Protein from Tetrahymena thermophila)
- Outer-arm dynein bound to microtubule doublet in microtubule binding state 2 (mtbs-2) (Complex from Tetrahymena thermophila)
- Dynein light chain (10 kDa, Protein from Tetrahymena thermophila)
- Dynein light chain 2a (14 kDa, Protein from Tetrahymena thermophila)
- Flagellar outer dynein arm intermediate protein, putative (63 kDa, Protein from Tetrahymena thermophila)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Gamma heavy chain (450 kDa, Protein from Tetrahymena thermophila)
Human cytoplasmic dynein-1 bound to dynactin and an N-terminal construct of BICD2
Resolution: 8.7 Å
EM Method: Single-particle
Fitted PDBs: 5nw4
Q-score: 0.113
Zhang K, Foster HE, Rondelet A, Lacey SE, Bahi-Buisson N, Bird AW, Carter AP
Cell (2017) 169 pp. 1303-1314.e18 [ Pubmed: 28602352 DOI: doi:10.1016/j.cell.2017.05.025 ]
- Dynactin shoulder complex (11 kDa, Protein from Sus scrofa)
- Dynein intermediate chain (29 kDa, Protein from Homo sapiens)
- Dynactin shoulder complex (51 kDa, Protein from Sus scrofa)
- Dynein intermediate chain (29 kDa, Protein from Homo sapiens)
- Arp11 (46 kDa, Protein from Sus scrofa)
- Dynactin (5 kDa, Protein from Sus scrofa)
- Dynactin (Complex from Sus scrofa)
- Dynactin (7 kDa, Protein from Sus scrofa)
- Dynein n-terminal dimerization domain (10 kDa, Protein from Homo sapiens)
- Dynein-1 (Complex from Homo sapiens)
- Dynactin shoulder complex (48 kDa, Protein from Sus scrofa)
- Capping protein (actin filament) muscle z-line, alpha 1 (33 kDa, Protein from Sus scrofa)
- Dynein light intermediate chain (25 kDa, Protein from Homo sapiens)
- Dynein heavy chain (75 kDa, Protein from Homo sapiens)
- F-actin capping protein beta subunit variant ii (33 kDa, Protein from Sus scrofa)
- Dynein light intermediate chain (25 kDa, Protein from Homo sapiens)
- Dynactin (3 kDa, Protein from Sus scrofa)
- Dynactin p150 (4 kDa, Protein from Sus scrofa)
- Human cytoplasmic dynein-1 bound to dynactin and an n-terminal construct of bicd2 (2 MDa, Complex)
- Robl (10 kDa, Protein from Homo sapiens)
- Dynactin shoulder complex (14 kDa, Protein from Sus scrofa)
- Dynactin pointed end p62 (20 kDa, Protein from Sus scrofa)
- Bicd2n (23 kDa, Protein from Homo sapiens)
- Bicd2 (Complex from Homo sapiens)
- Dynein heavy chain (78 kDa, Protein from Homo sapiens)
- Dynactin subunit 5 (24 kDa, Protein from Sus scrofa)
- Dynactin 6 (20 kDa, Protein from Sus scrofa)
- Arp1 (42 kDa, Protein from Sus scrofa)
- Dynein n-terminal dimerization domain (10 kDa, Protein from Homo sapiens)
- Dynactin (2 kDa, Protein from Sus scrofa)
- Beta-actin (43 kDa, Protein from Sus scrofa)
- P150 (4 kDa, Protein from Sus scrofa)
Human cytoplasmic dynein-1 tail in the twisted state
Resolution: 8.4 Å
EM Method: Single-particle
Fitted PDBs: 5nvs
Q-score: 0.028
Zhang K, Foster HE, Rondelet A, Lacey SE, Bahi-Buisson N, Bird AW, Carter AP
Cell (2017) 169 pp. 1303-1314.e18 [ Pubmed: 28602352 DOI: doi:10.1016/j.cell.2017.05.025 ]
- Tctex (8 kDa, Protein from Homo sapiens)
- Tctex (8 kDa, Protein from Homo sapiens)
- Intermediate chain (2 kDa, Protein from Homo sapiens)
- Dynein light intermediate chain (25 kDa, Protein from Homo sapiens)
- Dynein heavy chain (76 kDa, Protein from Homo sapiens)
- Dynein heavy chain (79 kDa, Protein from Homo sapiens)
- Dynein intermediate chain (29 kDa, Protein from Homo sapiens)
- N-terminal dimerization domain (10 kDa, Protein from Homo sapiens)
- Lc8 (7 kDa, Protein from Homo sapiens)
- N-terminal dimerization domain (10 kDa, Protein from Homo sapiens)
- Dynein light intermediate chain (25 kDa, Protein from Homo sapiens)
- Robl (10 kDa, Protein from Homo sapiens)
- Human cytoplasmic dynein-1 tail in the twisted n-terminus state (1 MDa, Complex from Homo sapiens)
- Intermediate chain (2 kDa, Protein from Homo sapiens)
Dynein motor domain in complex with Lis1 in the absence of nucleotide
Toropova K, Zou S, Roberts AJ, Redwine WB, Goodman BS, Reck-Peterson SL, Leschziner AE
eLife (2014) 3 pp. e03372-e03372 [ DOI: doi:10.7554/eLife.03372 Pubmed: 25380312 ]
- Dynein heavy chain (331 kDa, Protein from Saccharomyces cerevisiae)
- Lis1 (57 kDa, Protein from Saccharomyces cerevisiae)
- Dynein motor domain in complex with lis1 (445 kDa, Sample)
Dynein motor domain in the absence of nucleotide
Toropova K, Zou S, Roberts AJ, Redwine WB, Goodman BS, Reck-Peterson SL, Leschziner AE
eLife (2014) 3 pp. e03372-e03372 [ DOI: doi:10.7554/eLife.03372 Pubmed: 25380312 ]
- Dynein heavy chain (361 kDa, Protein from Saccharomyces cerevisiae)
- Dynein motor domain in the absence of nucleotide (361 kDa, Sample)
Dynein motor domain in the presence of ADP, with linker at position 2
Toropova K, Zou S, Roberts AJ, Redwine WB, Goodman BS, Reck-Peterson SL, Leschziner AE
eLife (2014) 3 pp. e03372-e03372 [ DOI: doi:10.7554/eLife.03372 Pubmed: 25380312 ]
- Dynein motor domain in 100 um adp (361 kDa, Sample)
- Dynein heavy chain (361 kDa, Protein from Saccharomyces cerevisiae)
Dynein motor domain in the presence of ADP, with linker at position 1
Toropova K, Zou S, Roberts AJ, Redwine WB, Goodman BS, Reck-Peterson SL, Leschziner AE
eLife (2014) 3 pp. e03372-e03372 [ DOI: doi:10.7554/eLife.03372 Pubmed: 25380312 ]
- Dynein motor domain in 100 um adp (361 kDa, Sample)
- Dynein heavy chain (361 kDa, Protein from Saccharomyces cerevisiae)
Dynein motor domain in complex with Lis1 in the presence of ATP and Vi
Toropova K, Zou S, Roberts AJ, Redwine WB, Goodman BS, Reck-Peterson SL, Leschziner AE
eLife (2014) 3 pp. e03372-e03372 [ DOI: doi:10.7554/eLife.03372 Pubmed: 25380312 ]
- Dynein heavy chain (331 kDa, Protein from Saccharomyces cerevisiae)
- Lis1 (57 kDa, Protein from Saccharomyces cerevisiae)
- Dynein motor domain in complex with lis1 in 500 um atp/navo4 (445 kDa, Sample)
Dynein motor domain with truncated linker in complex with Lis1 in the absence of nucleotide
Toropova K, Zou S, Roberts AJ, Redwine WB, Goodman BS, Reck-Peterson SL, Leschziner AE
eLife (2014) 3 pp. e03372-e03372 [ DOI: doi:10.7554/eLife.03372 Pubmed: 25380312 ]
- Dynein heavy chain (314 kDa, Protein from Saccharomyces cerevisiae)
- Lis1 (57 kDa, Protein from Saccharomyces cerevisiae)
- Dynein motor domain with truncated linker in complex with lis1 in the absence of nucleotide (428 kDa, Sample)