Cryo-EM structure of porcine brain ventricles cilia doublet microtubule (48-nm periodicity)
Leung MR, Sun C, Zeng J, Anderson JR, Niu Q, Huang W, Noteborn WEM, Brown A, Zeev-Ben-Mordehai T, Zhang R
Nature (2025) 637 pp. 1170-1177 [ DOI: doi:10.1038/s41586-024-08337-5 Pubmed: 39743588 ]
- Tektin (52 kDa, Protein from Sus scrofa)
- Meiosis-specific nuclear structural protein 1 (60 kDa, Protein from Sus scrofa)
- Cfap107/c1orf158 (23 kDa, Protein from Sus scrofa)
- Cilia and flagella associated protein 144 (16 kDa, Protein from Sus scrofa)
- Ciliary microtubule inner protein 2b (30 kDa, Protein from Sus scrofa)
- Sperm acrosome associated 9 (25 kDa, Protein from Sus scrofa)
- Efcab6 (167 kDa, Protein from Sus scrofa)
- Cilia from porcine brain ventricles (Cellular component from Sus scrofa)
- Nucleoside diphosphate kinase homolog 7 (42 kDa, Protein from Sus scrofa)
- Cilia and flagella associated protein 77 (32 kDa, Protein from Sus scrofa)
- Ciliary microtubule inner protein 2b (28 kDa, Protein from Sus scrofa)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Tubulin alpha chain (49 kDa, Protein from Sus scrofa)
- Cilia and flagella associated protein 210 (66 kDa, Protein from Sus scrofa)
- Rib43a-like with coiled-coils protein 1 (44 kDa, Protein from Sus scrofa)
- Tubulin beta chain (49 kDa, Protein from Sus scrofa)
- Cilia- and flagella-associated protein 45 (65 kDa, Protein from Sus scrofa)
- Piercer of microtubule wall 1 (15 kDa, Protein from Sus scrofa)
- Cilia- and flagella-associated protein 52 (68 kDa, Protein from Sus scrofa)
- Cilia- and flagella-associated protein 53 (62 kDa, Protein from Sus scrofa)
- Tektin (56 kDa, Protein from Sus scrofa)
- Chromosome 1 c9orf135 homolog (26 kDa, Protein from Sus scrofa)
- Armadillo repeat-containing protein 4 isoform 1 (116 kDa, Protein from Sus scrofa)
- Chromosome 1 c15orf65 homolog (13 kDa, Protein from Sus scrofa)
- Outer dynein arm docking complex subunit 3 (72 kDa, Protein from Sus scrofa)
- Parkin coregulated (29 kDa, Protein from Sus scrofa)
- Coiled-coil domain-containing protein 114 isoform x2 (80 kDa, Protein from Sus scrofa)
- Ef-hand domain containing 1 (74 kDa, Protein from Sus scrofa)
- Tektin (48 kDa, Protein from Sus scrofa)
- Ef-hand domain-containing family member c2 (87 kDa, Protein from Sus scrofa)
- Cilia-and flagella-associated protein 96 (34 kDa, Protein from Sus scrofa)
- Guanosine-5'-triphosphate (523 Da, Ligand from Sus scrofa)
- Sperm-associated antigen 8 isoform 1 (50 kDa, Protein from Sus scrofa)
- Outer dynein arm-docking complex subunit 4 (78 kDa, Protein from Sus scrofa)
- Rib43a domain with coiled-coils 2 (45 kDa, Protein from Sus scrofa)
- Enkurin (29 kDa, Protein from Sus scrofa)
- Tektin (49 kDa, Protein from Sus scrofa)
- Ef-hand domain family member b (98 kDa, Protein from Sus scrofa)
- Ef-hand calcium binding domain 1 (29 kDa, Protein from Sus scrofa)
- Cilia and flagella associated protein 161 (35 kDa, Protein from Sus scrofa)
- Cilia- and flagella-associated protein 20 (22 kDa, Protein from Sus scrofa)
- Cilia and flagella associated protein 141 (12 kDa, Protein from Sus scrofa)
- Cilia and flagella associated protein 276 (19 kDa, Protein from Sus scrofa)
- Protein flattop (19 kDa, Protein from Sus scrofa)
Composite cryo-EM density map of the 48-nm repeat doublet microtubule from bovine tracheal cilia
Gui M, Farley H, Anujan P, Anderson JR, Maxwell DW, Whitchurch JB, Botsch JJ, Qiu T, Meleppattu S, Singh SK, Zhang Q, Thompson J, Lucas JS, Bingle CD, Norris DP, Roy S, Brown A
Cell (2021) 184 pp. 5791- [ DOI: doi:10.1016/j.cell.2021.10.007 Pubmed: 34715025 ]
- Nucleoside diphosphate kinase 7 (42 kDa, Protein from Bos taurus)
- Pacrg protein (29 kDa, Protein from Bos taurus)
- Tektin-2 (49 kDa, Protein from Bos taurus)
- Tubulin alpha-1d chain (50 kDa, Protein from Bos taurus)
- Cilia and flagella associated protein 52 (68 kDa, Protein from Bos taurus)
- Outer dynein arm-docking complex subunit 3 (72 kDa, Protein from Bos taurus)
- Efhc2 (85 kDa, Protein from Bos taurus)
- Efcab6 (172 kDa, Protein from Bos taurus)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Sperm associated antigen 8 (51 kDa, Protein from Bos taurus)
- Ef-hand domain family member b (97 kDa, Protein from Bos taurus)
- Tektin-3 (56 kDa, Protein from Bos taurus)
- Pierce2 (13 kDa, Protein from Bos taurus)
- Ef-hand calcium-binding domain-containing protein 1 (24 kDa, Protein from Bos taurus)
- Cilia and flagella associated protein 161 (36 kDa, Protein from Bos taurus)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Cilia and flagella associated protein 45 (65 kDa, Protein from Bos taurus)
- Cilia- and flagella-associated protein 20 (22 kDa, Protein from Bos taurus)
- Chromosome 3 c1orf194 homolog (19 kDa, Protein from Bos taurus)
- Doublet microtubule (Complex from Bos taurus)
- Uncharacterized protein c1orf158 homolog (23 kDa, Protein from Bos taurus)
- Rib43a-like with coiled-coils protein 2 (44 kDa, Protein from Bos taurus)
- Ef-hand domain containing 1 (74 kDa, Protein from Bos taurus)
- Tektin-4 (52 kDa, Protein from Bos taurus)
- Tektin-1 (48 kDa, Protein from Bos taurus)
- Tubulin beta-4b chain (49 kDa, Protein from Bos taurus)
- Meiosis-specific nuclear structural protein 1 (60 kDa, Protein from Bos taurus)
- Protein fam166b (30 kDa, Protein from Bos taurus)
- Protein c9orf135 homolog (26 kDa, Protein from Bos taurus)
- Coiled-coil domain containing 173 (65 kDa, Protein from Bos taurus)
- Methyl-cpg binding domain protein 1 (62 kDa, Protein from Bos taurus)
- Coiled-coil domain containing 114 (77 kDa, Protein from Bos taurus)
- Uncharacterized protein c1orf189 homolog (12 kDa, Protein from Bos taurus)
- Enkurin, trpc channel interacting protein (30 kDa, Protein from Bos taurus)
- Ttc25 protein (78 kDa, Protein from Bos taurus)
- Pierce1 (15 kDa, Protein from Bos taurus)
- Protein flattop (21 kDa, Protein from Bos taurus)
- Magnesium ion (24 Da, Ligand)
- Tektip1 (24 kDa, Protein from Bos taurus)
- Armadillo repeat containing 4 (116 kDa, Protein from Bos taurus)