Cryo-EM map of Hrd1/Hrd3 monomer
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 6vjy
Q-score: 0.334
Wu X, Siggel M, Ovchinnikov S, Mi W, Svetlov V, Nudler E, Liao M, Hummer G, Rapoport TA
Science (2020) 368 [ Pubmed: 32327568 DOI: doi:10.1126/science.aaz2449 ]
CryoEM map of Hrd1-Usa1/Der1/Hrd3 complex of the expected topology
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 6vjz
Q-score: 0.334
Wu X, Siggel M, Ovchinnikov S, Mi W, Svetlov V, Nudler E, Liao M, Hummer G, Rapoport TA
Science (2020) 368 [ Pubmed: 32327568 DOI: doi:10.1126/science.aaz2449 ]
- U1 snp1-associating protein 1 (39 kDa, Protein from Saccharomyces cerevisiae)
- Degradation in the endoplasmic reticulum protein 1 (24 kDa, Protein from Saccharomyces cerevisiae)
- Erad-associated e3 ubiquitin-protein ligase component hrd3 (88 kDa, Protein from Saccharomyces cerevisiae)
- Erad-associated e3 ubiquitin-protein ligase hrd1 (55 kDa, Protein from Saccharomyces cerevisiae)
- Complex of hrd1-usa1/der1/hrd3 in the expected topology (Complex from Saccharomyces cerevisiae)
CryoEM map of Hrd1-Usa1/Der1/Hrd3 of the flipped topology
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 6vk0
Q-score: 0.369
Wu X, Siggel M, Ovchinnikov S, Mi W, Svetlov V, Nudler E, Liao M, Hummer G, Rapoport TA
Science (2020) 368 [ Pubmed: 32327568 DOI: doi:10.1126/science.aaz2449 ]
- U1 snp1-associating protein 1 (39 kDa, Protein from Saccharomyces cerevisiae)
- Complex of hrd1-usa1/der1/hrd3 of the flipped topology (Complex from Saccharomyces cerevisiae)
- Erad-associated e3 ubiquitin-protein ligase component hrd3 (88 kDa, Protein from Saccharomyces cerevisiae)
- Degradation in the endoplasmic reticulum protein 1 (24 kDa, Protein from Saccharomyces cerevisiae)
- Erad-associated e3 ubiquitin-protein ligase hrd1 (55 kDa, Protein from Saccharomyces cerevisiae)
CryoEM map of Hrd1/Hrd3 part from Hrd1-Usa1/Der1/Hrd3 complex
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 6vk1
Q-score: 0.401
Wu X, Siggel M, Ovchinnikov S, Mi W, Svetlov V, Nudler E, Liao M, Hummer G, Rapoport TA
Science (2020) 368 [ Pubmed: 32327568 DOI: doi:10.1126/science.aaz2449 ]
Cryo-EM map of the ERAD components Hrd1/Hrd3 dimer
Schoebel S, Mi W, Stein A, Ovchinnikov S, Pavlovicz R, DiMaio F, Baker D, Chambers MG, Su H, Li D, Rapoport TA, Liao M
Nature (2017) 548 pp. 352-355 [ Pubmed: 28682307 DOI: doi:10.1038/nature23314 ]
CryoEM map of Hrd1 dimer with one Hrd3 molecule
Schoebel S, Mi W, Stein A, Ovchinnikov S, Pavlovicz R, DiMaio F, Baker D, Chambers MG, Su H, Li D, Rapoport TA, Liao M
Nature (2017) 548 pp. 352-355 [ Pubmed: 28682307 DOI: doi:10.1038/nature23314 ]
Cryo-EM structure of ERAD-associated E3 ubiquitin-protein ligase component HRD3
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 5v7v
Q-score: 0.396
Schoebel S, Mi W, Stein A, Ovchinnikov S, Pavlovicz R, DiMaio F, Baker D, Chambers MG, Su H, Li D, Rapoport TA, Liao M
Nature (2017) 548 pp. 352-355 [ Pubmed: 28682307 DOI: doi:10.1038/nature23314 ]