Cryo-EM structure of enterovirus A71 mature virion in complex with Fab h1A6.2
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ Pubmed: 39424982 DOI: doi:10.1038/s41564-024-01822-7 ]
- Enterovirus a71 (Virus from Enterovirus A71)
- Capsid protein vp2 (27 kDa, Protein from Enterovirus A71)
- Capsid protein vp4 (7 kDa, Protein from Enterovirus A71)
- Capsid protein vp1 (32 kDa, Protein from Enterovirus A71)
- Sphingosine (299 Da, Ligand)
- Enterovirus a71 mature virion in complex with fab h1a6.2 (Complex)
- Fab h1a6.2 (Complex from Mus)
- Capsid protein vp3 (26 kDa, Protein from Enterovirus A71)
Cryo-EM structure of enterovirus A71 A-particle in complex with Fab h1A6.2
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ Pubmed: 39424982 DOI: doi:10.1038/s41564-024-01822-7 ]
- Enterovirus a71 (Virus from Enterovirus A71)
- Enterovirus 71 a-particle in complex with fab h1a6.2 (Complex)
- Capsid protein vp2 (27 kDa, Protein from Enterovirus A71)
- Capsid protein vp1 (32 kDa, Protein from Enterovirus A71)
- Fab h1a6.2 (Complex from Mus)
- Capsid protein vp3 (26 kDa, Protein from Enterovirus A71)
Cryo-EM structure of enterovirus A71 empty particle in complex with Fab h1A6.2
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ Pubmed: 39424982 DOI: doi:10.1038/s41564-024-01822-7 ]
- Enterovirus a71 (Virus from Enterovirus A71)
- Enterovirus a71 empty particle in complex with fab h1a6.2 (Complex)
- Capsid protein vp2 (27 kDa, Protein from Enterovirus A71)
- The fab of h1a6.2 (Complex from Mus)
- Capsid protein vp1 (32 kDa, Protein from Enterovirus A71)
- Capsid protein vp3 (26 kDa, Protein from Enterovirus A71)
Cryo-EM structure of enterovirus A71 empty particle
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ Pubmed: 39424982 DOI: doi:10.1038/s41564-024-01822-7 ]
- Enterovirus a71 (Virus from Enterovirus A71)
- Capsid protein vp2 (27 kDa, Protein from Enterovirus A71)
- Capsid protein vp3 (26 kDa, Protein from Enterovirus A71)
- Capsid protein vp1 (32 kDa, Protein from Enterovirus A71)
Cryo-EM structure of enterovirus A71 mature virion
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ Pubmed: 39424982 DOI: doi:10.1038/s41564-024-01822-7 ]
- Enterovirus a71 (Virus from Enterovirus A71)
- Capsid protein vp2 (27 kDa, Protein from Enterovirus A71)
- Capsid protein vp4 (7 kDa, Protein from Enterovirus A71)
- Capsid protein vp1 (32 kDa, Protein from Enterovirus A71)
- Sphingosine (299 Da, Ligand)
- Capsid protein vp3 (26 kDa, Protein from Enterovirus A71)
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 9f5s
Q-score: 0.638
Kingston NJ, Snowden JS, Grehan K, Hall PK, Hietanen EV, Passchier TC, Polyak SJ, Filman DJ, Hogle JM, Rowlands DJ, Stonehouse NJ
PLoS Pathog (2024) 20 pp. e1012511-e1012511 [ DOI: doi:10.1371/journal.ppat.1012511 Pubmed: 39298524 ]
- Vp0 (35 kDa, Protein from Enterovirus A71)
- Enterovirus a71 (Virus from Enterovirus A71)
- Vp3 (26 kDa, Protein from Enterovirus A71)
- Sphingosine (299 Da, Ligand)
- Vp1 (32 kDa, Protein from Enterovirus A71)
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 9f6a
Q-score: 0.61
Kingston NJ, Snowden JS, Grehan K, Hall PK, Hietanen EV, Passchier TC, Polyak SJ, Filman DJ, Hogle JM, Rowlands DJ, Stonehouse NJ
PLoS Pathog (2024) 20 pp. e1012511-e1012511 [ DOI: doi:10.1371/journal.ppat.1012511 Pubmed: 39298524 ]
- Vp0 (35 kDa, Protein from Enterovirus A71)
- Enterovirus a71 (Virus from Enterovirus A71)
- Vp3 (26 kDa, Protein from Enterovirus A71)
- Sphingosine (299 Da, Ligand)
- Vp1 (32 kDa, Protein from Enterovirus A71)
Structure of enterovirus protease in complex host factor
Resolution: 3.14 Å
EM Method: Single-particle
Fitted PDBs: 8x8q
Q-score: 0.544
Gao X, Wang B, Zhu K, Wang L, Qin B, Shang K, Ding W, Wang J, Cui S
Nat Commun (2024) 15 pp. 4176-4176 [ Pubmed: 38755176 DOI: doi:10.1038/s41467-024-48504-w ]
- 2a protein (fragment) (16 kDa, Protein from Enterovirus A71)
- Zinc ion (65 Da, Ligand)
- Actin-histidine n-methyltransferase (67 kDa, Protein from Homo sapiens)
- Enterovirus protease in complex host factor (Complex from Enterovirus A71)
Purification of Enterovirus A71, strain 4643, WT capsid
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8e2x
Q-score: 0.54
Catching A, Te Yeh M, Bianco S, Capponi S, Andino R
Nat Commun (2023) 14 pp. 7450-7450 [ DOI: doi:10.1038/s41467-023-43029-0 Pubmed: 37978288 ]
- Vp2 (27 kDa, Protein from Human enterovirus 71)
- Human enterovirus 71 (Virus from Human enterovirus 71)
- Vp3 (26 kDa, Protein from Human enterovirus 71)
- Vp4 (7 kDa, Protein from Human enterovirus 71)
- Vp1 (32 kDa, Protein from Human enterovirus 71)
- Sphingosine (299 Da, Ligand)
Purification of Enterovirus A71, strain 4643, WT capsid
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 8e38
Q-score: 0.363
Catching A, Te Yeh M, Bianco S, Capponi S, Andino R
Nat Commun (2023) 14 pp. 7450-7450 [ DOI: doi:10.1038/s41467-023-43029-0 Pubmed: 37978288 ]
- Vp2 (27 kDa, Protein from Human enterovirus 71)
- Human enterovirus 71 (Virus from Human enterovirus 71)
- Vp3 (26 kDa, Protein from Human enterovirus 71)
- Vp1 (32 kDa, Protein from Human enterovirus 71)
- Vp4 (7 kDa, Protein from Human enterovirus 71)
- Sphingosine (299 Da, Ligand)