SARS-CoV-2 S/S2M11/S2X333 Local Refinement
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7lxw
Q-score: 0.522
McCallum M, De Marco A, Lempp FA, Tortorici MA, Pinto D, Walls AC, Beltramello M, Chen A, Liu Z, Zatta F, Zepeda S, di Iulio J, Bowen JE, Montiel-Ruiz M, Zhou J, Rosen LE, Bianchi S, Guarino B, Fregni CS, Abdelnabi R, Foo SC, Rothlauf PW, Bloyet LM, Benigni F, Cameroni E, Neyts J, Riva A, Snell G, Telenti A, Whelan SPJ, Virgin HW, Corti D, Pizzuto MS, Veesler D
Cell (2021) 184 pp. 2332- [ Pubmed: 33761326 DOI: doi:10.1016/j.cell.2021.03.028 ]
- Sars-cov-2 s hexapro bound to s2x333 fab (Complex from Homo sapiens)
- S2x333 fab heavy chain variable region (13 kDa, Protein from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- S2x333 fab light chain variable region (10 kDa, Protein from Homo sapiens)
SARS-CoV-2 S/S2M11/S2L28 Local Refinement
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7lxx
Q-score: 0.507
McCallum M, De Marco A, Lempp FA, Tortorici MA, Pinto D, Walls AC, Beltramello M, Chen A, Liu Z, Zatta F, Zepeda S, di Iulio J, Bowen JE, Montiel-Ruiz M, Zhou J, Rosen LE, Bianchi S, Guarino B, Fregni CS, Abdelnabi R, Foo SC, Rothlauf PW, Bloyet LM, Benigni F, Cameroni E, Neyts J, Riva A, Snell G, Telenti A, Whelan SPJ, Virgin HW, Corti D, Pizzuto MS, Veesler D
Cell (2021) 184 pp. 2332- [ Pubmed: 33761326 DOI: doi:10.1016/j.cell.2021.03.028 ]
- Sars-cov-2 s hexapro bound to s2l28 fab (Complex from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- S2l28 fab heavy chain variable region (13 kDa, Protein from Homo sapiens)
- S2l28 fab light chain variable region (11 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
SARS-CoV-2 S/S2M11/S2X333 Global Refinement
Resolution: 2.2 Å
EM Method: Single-particle
Fitted PDBs: 7lxy
Q-score: 0.58
McCallum M, De Marco A, Lempp FA, Tortorici MA, Pinto D, Walls AC, Beltramello M, Chen A, Liu Z, Zatta F, Zepeda S, di Iulio J, Bowen JE, Montiel-Ruiz M, Zhou J, Rosen LE, Bianchi S, Guarino B, Fregni CS, Abdelnabi R, Foo SC, Rothlauf PW, Bloyet LM, Benigni F, Cameroni E, Neyts J, Riva A, Snell G, Telenti A, Whelan SPJ, Virgin HW, Corti D, Pizzuto MS, Veesler D
Cell (2021) 184 pp. 2332- [ Pubmed: 33761326 DOI: doi:10.1016/j.cell.2021.03.028 ]
- S2x333 fab heavy chain variable region (13 kDa, Protein from Homo sapiens)
- S2m11 fab light chain variable region (11 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- S2m11 fab heavy chain variable region (13 kDa, Protein from Homo sapiens)
- S2x333 fab light chain variable region (10 kDa, Protein from Homo sapiens)
- Sars-cov-2 s hexapro bound to s2x333 fab (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
SARS-CoV-2 S/S2M11/S2L28 Global Refinement
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 7lxz
Q-score: 0.54
McCallum M, De Marco A, Lempp FA, Tortorici MA, Pinto D, Walls AC, Beltramello M, Chen A, Liu Z, Zatta F, Zepeda S, di Iulio J, Bowen JE, Montiel-Ruiz M, Zhou J, Rosen LE, Bianchi S, Guarino B, Fregni CS, Abdelnabi R, Foo SC, Rothlauf PW, Bloyet LM, Benigni F, Cameroni E, Neyts J, Riva A, Snell G, Telenti A, Whelan SPJ, Virgin HW, Corti D, Pizzuto MS, Veesler D
Cell (2021) 184 pp. 2332- [ Pubmed: 33761326 DOI: doi:10.1016/j.cell.2021.03.028 ]
- Sars-cov-2 s hexapro bound to s2l28 fab (Complex from Homo sapiens)
- S2m11 fab light chain variable region (11 kDa, Protein from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- S2m11 fab heavy chain variable region (13 kDa, Protein from Homo sapiens)
- S2l28 fab heavy chain variable region (13 kDa, Protein from Homo sapiens)
- S2l28 fab light chain variable region (11 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
SARS-CoV-2 S/S2M11/S2M28 Local Refinement
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 7ly0
Q-score: 0.529
McCallum M, De Marco A, Lempp FA, Tortorici MA, Pinto D, Walls AC, Beltramello M, Chen A, Liu Z, Zatta F, Zepeda S, di Iulio J, Bowen JE, Montiel-Ruiz M, Zhou J, Rosen LE, Bianchi S, Guarino B, Fregni CS, Abdelnabi R, Foo SC, Rothlauf PW, Bloyet LM, Benigni F, Cameroni E, Neyts J, Riva A, Snell G, Telenti A, Whelan SPJ, Virgin HW, Corti D, Pizzuto MS, Veesler D
Cell (2021) 184 pp. 2332- [ Pubmed: 33761326 DOI: doi:10.1016/j.cell.2021.03.028 ]
- S2m28 fab heavy chain variable region (13 kDa, Protein from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- S2m28 fab light chain variable region (11 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sars-cov-2 s hexapro bound to s2m28 fab (Complex from Homo sapiens)
SARS-CoV-2 S/S2M11/S2M28 Global Refinement
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 7ly2
Q-score: 0.551
McCallum M, De Marco A, Lempp FA, Tortorici MA, Pinto D, Walls AC, Beltramello M, Chen A, Liu Z, Zatta F, Zepeda S, di Iulio J, Bowen JE, Montiel-Ruiz M, Zhou J, Rosen LE, Bianchi S, Guarino B, Fregni CS, Abdelnabi R, Foo SC, Rothlauf PW, Bloyet LM, Benigni F, Cameroni E, Neyts J, Riva A, Snell G, Telenti A, Whelan SPJ, Virgin HW, Corti D, Pizzuto MS, Veesler D
Cell (2021) 184 pp. 2332- [ Pubmed: 33761326 DOI: doi:10.1016/j.cell.2021.03.028 ]
- S2m11 fab light chain variable region (11 kDa, Protein from Homo sapiens)
- S2m28 fab heavy chain variable region (13 kDa, Protein from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- S2m11 fab heavy chain variable region (13 kDa, Protein from Homo sapiens)
- S2m28 fab light chain variable region (11 kDa, Protein from Homo sapiens)
- Sars-cov-2 s hexapro bound to s2m11 and s2m28 fabs (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
BG505 SOSIP.v5.2 in complex with rhesus macaque Fab RM20E1 and PGT122 Fab
Resolution: 4.42 Å
EM Method: Single-particle
Fitted PDBs: 6vlr
Q-score: 0.337
Cottrell CA, van Schooten J, Bowman CA, Yuan M, Oyen D, Shin M, Morpurgo R, van der Woude P, van Breemen M, Torres JL, Patel R, Gross J, Sewall LM, Copps J, Ozorowski G, Nogal B, Sok D, Rakasz EG, Labranche C, Vigdorovich V, Christley S, Carnathan DG, Sather DN, Montefiori D, Silvestri G, Burton DR, Moore JP, Wilson IA, Sanders RW, Ward AB, van Gils MJ
PLoS Pathog (2020) 16 pp. e1008753-e1008753 [ Pubmed: 32866207 DOI: doi:10.1371/journal.ppat.1008753 ]
- Rm20e1 fab kappa chain (12 kDa, Protein from Macaca mulatta)
- Rm20e1 fab heavy chain (13 kDa, Protein from Macaca mulatta)
- Pgt122 fab heavy chain (14 kDa, Protein from Homo sapiens)
- Envelope glycoprotein gp120 (53 kDa, Protein from Human immunodeficiency virus 1)
- Pgt122 fab light chain (11 kDa, Protein from Homo sapiens)
- Bg505 sosipv5.2 gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Bg505 sosip.v5.2 in complex with rhesus macaque fab rm20e1 (Complex from Human immunodeficiency virus 1)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 6ukj
Q-score: 0.505
Kim J, Tan YZ, Wicht KJ, Erramilli SK, Dhingra SK, Okombo J, Vendome J, Hagenah LM, Giacometti SI, Warren AL, Nosol K, Roepe PD, Potter CS, Carragher B, Kossiakoff AA, Quick M, Fidock DA, Mancia F
Nature (2019) 576 pp. 315-320 [ DOI: doi:10.1038/s41586-019-1795-x Pubmed: 31776516 ]
- Antigen-binding fragment (fab) (50 kDa, Cellular component from Homo sapiens)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Plasmodium falciparum chloroquine resistance transporter (pfcrt) 7g8 isoform complexed with fab (102 kDa, Cellular component)
- Plasmodium falciparum chloroquine resistance transporter (pfcrt) (49 kDa, Cellular component from Plasmodium falciparum 7G8)
- Fab heavy chain (25 kDa, Protein from Homo sapiens)
- Fab light chain (23 kDa, Protein from Homo sapiens)
- Chloroquine resistance transporter (53 kDa, Protein from Plasmodium falciparum (isolate 7G8))