HIV-1 BG505 Env SOSIP in complex with bovine Fab Bess4 and non-human primate Fab RM20A3
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8tq1
Q-score: 0.512
Altman PX, Ozorowski G, Stanfield RL, Haakenson J, Appel M, Parren M, Lee WH, Sang H, Woehl J, Saye-Francisco K, Sewall LM, Joyce C, Song G, Porter K, Landais E, Andrabi R, Wilson IA, Ward AB, Mwangi W, Smider VV, Burton DR, Sok D
PLoS Pathog (2024) 20 pp. e1012042-e1012042 [ DOI: doi:10.1371/journal.ppat.1012042 Pubmed: 39250525 ]
- Nhp rm20a3 fab heavy chain (13 kDa, Protein from Macaca mulatta)
- Nhp rm20a3 fab light chain (13 kDa, Protein from Macaca mulatta)
- Hiv-1 bg505 sosip env in complex with bovine bess4 fab and nhp rm20a3 fab (Complex from Human immunodeficiency virus 1)
- Transmembrane protein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Bovine bess4 fab heavy chain (17 kDa, Protein from Bos taurus)
- Hiv-1 envelope glycoprotein bg505 sosip.664 gp120 (57 kDa, Protein from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, M8a-3
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7uz4
Q-score: 0.368
Fan C, Cohen AA, Park M, Hung AF, Keeffe JR, Gnanapragasam PNP, Lee YE, Gao H, Kakutani LM, Wu Z, Kleanthous H, Malecek KE, Williams JC, Bjorkman PJ
Immunity (2022) 55 pp. 2419- [ Pubmed: 36370711 DOI: doi:10.1016/j.immuni.2022.10.019 ]
- Sars-cov-2 s 6p in complex with m8a-3 fab (25 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- M8a-3 fab heavy chain (25 kDa, Protein from Mus musculus)
- Severe acute respiratory syndrome coronavirus 2 spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- M8a-3 fab ch1 and cl domains (Complex from Mus musculus)
- M8a-3 fab light chain (23 kDa, Protein from Mus musculus)
- Spike glycoprotein (139 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- M8a-3 fab vh and vl domains (Complex from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, M8a-6
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7uz5
Q-score: 0.355
Fan C, Cohen AA, Park M, Hung AF, Keeffe JR, Gnanapragasam PNP, Lee YE, Gao H, Kakutani LM, Wu Z, Kleanthous H, Malecek KE, Williams JC, Bjorkman PJ
Immunity (2022) 55 pp. 2419- [ Pubmed: 36370711 DOI: doi:10.1016/j.immuni.2022.10.019 ]
- M8a-6 fab vh and vl domains (Complex from Mus musculus)
- M8a-6 fab ch1 and cl domains (Complex from Mus musculus)
- M8a-6 fab heavy chain (25 kDa, Protein from Mus musculus)
- Sars-cov-2 s 6p in complex with m8a-6 fab (25 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- Severe acute respiratory syndrome coronavirus 2 spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (139 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- M8a-6 fab light chain (23 kDa, Protein from Mus musculus)
Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, M8a-28
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7uz6
Q-score: 0.477
Fan C, Cohen AA, Park M, Hung AF, Keeffe JR, Gnanapragasam PNP, Lee YE, Gao H, Kakutani LM, Wu Z, Kleanthous H, Malecek KE, Williams JC, Bjorkman PJ
Immunity (2022) 55 pp. 2419- [ Pubmed: 36370711 DOI: doi:10.1016/j.immuni.2022.10.019 ]
- M8a-28 fab ch1 and cl domains (Complex from Mus musculus)
- Sars-cov-2 s 6p in complex with m8a-28 fab (25 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- M8a-28 fab heavy chain (25 kDa, Protein from Mus musculus)
- M8a-28 fab light chain (23 kDa, Protein from Mus musculus)
- Severe acute respiratory syndrome coronavirus 2 spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (139 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- M8a-28 fab vh and vl domains (Complex from Mus musculus)
Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, M8a-31
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7uz7
Q-score: 0.36
Fan C, Cohen AA, Park M, Hung AF, Keeffe JR, Gnanapragasam PNP, Lee YE, Gao H, Kakutani LM, Wu Z, Kleanthous H, Malecek KE, Williams JC, Bjorkman PJ
Immunity (2022) 55 pp. 2419- [ Pubmed: 36370711 DOI: doi:10.1016/j.immuni.2022.10.019 ]
- M8a-31 fab light chain (24 kDa, Protein from Mus musculus)
- M8a-31 fab vh and vl domains (Complex from Mus musculus)
- M8a-31 fab heavy chain (24 kDa, Protein from Mus musculus)
- M8a-31 fab ch1 and cl domains (Complex from Mus musculus)
- Severe acute respiratory syndrome coronavirus 2 spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 s 6p in complex with m8a-31 fab (25 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (139 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7uz8
Q-score: 0.35
Fan C, Cohen AA, Park M, Hung AF, Keeffe JR, Gnanapragasam PNP, Lee YE, Gao H, Kakutani LM, Wu Z, Kleanthous H, Malecek KE, Williams JC, Bjorkman PJ
Immunity (2022) 55 pp. 2419- [ Pubmed: 36370711 DOI: doi:10.1016/j.immuni.2022.10.019 ]
- M8a-31 fab light chain (24 kDa, Protein from Mus musculus)
- M8a-31 fab vh and vl domains (Complex from Mus musculus)
- M8a-31 fab heavy chain (24 kDa, Protein from Mus musculus)
- M8a-31 fab ch1 and cl domains (Complex from Mus musculus)
- Spike glycoprotein (139 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 omicron ba.1 s 6p in complex with m8a-31 fab (25 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- Severe acute respiratory syndrome coronavirus 2 omicron spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, M8a-34
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7uz9
Q-score: 0.289
Fan C, Cohen AA, Park M, Hung AF, Keeffe JR, Gnanapragasam PNP, Lee YE, Gao H, Kakutani LM, Wu Z, Kleanthous H, Malecek KE, Williams JC, Bjorkman PJ
Immunity (2022) 55 pp. 2419- [ Pubmed: 36370711 DOI: doi:10.1016/j.immuni.2022.10.019 ]
- M8a-34 fab ch1 and cl domains (Complex from Mus musculus)
- M8a-34 fab heavy chain (25 kDa, Protein from Mus musculus)
- M8a-34 fab light chain (23 kDa, Protein from Mus musculus)
- Severe acute respiratory syndrome coronavirus 2 spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- M8a-34 fab vh and vl domains (Complex from Mus musculus)
- Spike glycoprotein (139 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 s 6p in complex with m8a-34 fab (25 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, HSW-1
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7uza
Q-score: 0.377
Fan C, Cohen AA, Park M, Hung AF, Keeffe JR, Gnanapragasam PNP, Lee YE, Gao H, Kakutani LM, Wu Z, Kleanthous H, Malecek KE, Williams JC, Bjorkman PJ
Immunity (2022) 55 pp. 2419- [ Pubmed: 36370711 DOI: doi:10.1016/j.immuni.2022.10.019 ]
- Hsw-1 fab ch1 and cl domains (Complex from Mus musculus)
- Sars-cov-2 s 6p in complex with hsw-1 fab (25 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- Hsw-1 fab light chain (23 kDa, Protein from Mus musculus)
- Hsw-1 fab heavy chain (25 kDa, Protein from Mus musculus)
- Severe acute respiratory syndrome coronavirus 2 spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (139 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Hsw-1 fab vh and vl domains (Complex from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of the SARS-CoV-2 S S1 doamin in complex with the mouse antibody Fab fragment, HSW-2
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 7uzb
Q-score: 0.334
Fan C, Cohen AA, Park M, Hung AF, Keeffe JR, Gnanapragasam PNP, Lee YE, Gao H, Kakutani LM, Wu Z, Kleanthous H, Malecek KE, Williams JC, Bjorkman PJ
Immunity (2022) 55 pp. 2419- [ Pubmed: 36370711 DOI: doi:10.1016/j.immuni.2022.10.019 ]
- Hsw-2 fab heavy chain (24 kDa, Protein from Mus musculus)
- Hsw-2 fab vh and vl domains (Complex from Mus musculus)
- Hsw-2 fab light chain (23 kDa, Protein from Mus musculus)
- Severe acute respiratory syndrome coronavirus 2 spike glycoprotein s1 domain (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (139 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Hsw-2 fab ch1 and cl domains (Complex from Mus musculus)
- Sars-cov-2 s 6p in complex with hsw-2 fab (25 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
Resolution: 3.47 Å
EM Method: Single-particle
Fitted PDBs: 7t2p
Q-score: 0.422
Zhao F, Berndsen ZT, Pedreno-Lopez N, Burns A, Allen JD, Barman S, Lee WH, Chakraborty S, Gnanakaran S, Sewall LM, Ozorowski G, Limbo O, Song G, Yong P, Callaghan S, Coppola J, Weisgrau KL, Lifson JD, Nedellec R, Voigt TB, Laurino F, Louw J, Rosen BC, Ricciardi M, Crispin M, Desrosiers RC, Rakasz EG, Watkins DI, Andrabi R, Ward AB, Burton DR, Sok D
Nat Commun (2022) 13 pp. 5236-5236 [ DOI: doi:10.1038/s41467-022-32783-2 Pubmed: 36068229 ]
- K11 fab light chain (25 kDa, Protein from Macaca mulatta)
- K11 fab heavy chain (53 kDa, Protein from Macaca mulatta)
- Envelope glycoprotein gp41 (18 kDa, Protein from Simian immunodeficiency virus)
- Envelope glycoprotein gp120 (60 kDa, Protein from Simian immunodeficiency virus)
- Sivmac239.k180s sosip trimer in complex with 3 copies of k11 fab (Complex from Simian immunodeficiency virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)