Resolution: 3.06 Å
EM Method: Single-particle
Fitted PDBs: 8znz
Q-score: 0.547
Xu JG, Chen S, He Y, Zhu X, Wang Y, Ye Z, Zhou JC, Wu X, Zhang L, Ren X, Jia H, Yu H, Wei X, Feng Y, Chen X, Cui X, Pan X, Wang S, Xia S, Shang H, Pu Y, Xu W, Li H, Chen Q, Chen Z, Wang M, Yan X, Shi H, Li M, Xia Y, Bellelli R, Dong S, He J, Huang J, Cai CL, Zhu X, Zhan Y, Wan L
Nat Commun (2024) 15 pp. 10872-10872 [ DOI: doi:10.1038/s41467-024-55207-9 Pubmed: 39738003 ]
- Zinc ion (65 Da, Ligand)
- Hb0038 fab light chain (11 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Hb0038 fab heavy chain (13 kDa, Protein from Homo sapiens)
- Hb0039 fab light chain (11 kDa, Protein from Homo sapiens)
- Sodium ion (22 Da, Ligand)
- Hb0039 fab heavy chain (13 kDa, Protein from Homo sapiens)
- Cd73 complexed with hb0017 antibody coaktail (630 kDa, Complex from Homo sapiens)
- 5'-nucleotidase (58 kDa, Protein from Homo sapiens)
Fibriansah G, Ng TS, Lim XN, Tan AWK, Shi J, Crowe JE, Lok SM
To Be Published
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Dengue serotype 2 strain d2y98p-pp1 n153q mutant (Complex from dengue virus type 2)
- Envelope protein (54 kDa, Protein from dengue virus type 2)
- Dengue virus serotype 2 strain y98p-pp1 n153q mutant in complex with human antibody 2d22 fab at 37 deg c (Complex)
- Human antibody 2d22 fab (heavy and light chains) (Complex from Homo sapiens)
- Membrane polyprotein (8 kDa, Protein from dengue virus type 2)
- Human antibody 2d22 fab heavy chain (13 kDa, Protein from Homo sapiens)
- Human antibody 2d22 fab light chain (12 kDa, Protein from Homo sapiens)
Fibriansah G, Ng TS, Lim XN, Tan AWK, Shi J, Crowe JE, Lok SM
To Be Published
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Membrane protein (8 kDa, Protein from dengue virus type 2)
- Dengue serotype 2 strain d2y98p-pp1 n153q mutant (Complex from dengue virus type 2)
- Envelope protein (54 kDa, Protein from dengue virus type 2)
- Human antibody c10 fab (light chain) (11 kDa, Protein from Homo sapiens)
- Human antibody c10 fab (heavy chain) (14 kDa, Protein from Homo sapiens)
- Human antibody c10 fab (heavy and light chains) (Complex from Homo sapiens)
- Dengue virus serotype 2 strain y98p-pp1 n153q mutant in complex with human antibody c10 fab at 37 deg c (Complex)
Fibriansah G, Ng TS, Lim XN, Tan AWK, Shi J, Crowe JE, Lok SM
To Be Published
- Human antibody 2d22 fab (heavy chain) (13 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Dengue virus serotype 2 strain d2y98p-pp1 in complex with human antibody 2d22 fab at 37 deg c (Complex)
- Envelope protein (54 kDa, Protein from dengue virus type 2)
- Human antibody 2d22 fab (light chain) (12 kDa, Protein from Homo sapiens)
- Human antibody 2d22 fab (heavy and light chains) (Complex from Homo sapiens)
- Dengue serotype 2 strain d2y98p-pp1 (Complex from dengue virus type 2)
- Membrane polyprotein (8 kDa, Protein from dengue virus type 2)
Fibriansah G, Ng TS, Lim XN, Tan AWK, Shi J, Crowe JE, Lok SM
To Be Published
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Envelope protein (54 kDa, Protein from dengue virus type 2)
- Dengue virus type 2 (Virus)
- Human antibody c10 fab (light chain) (11 kDa, Protein from Homo sapiens)
- Dengue serotype 2 strain d2y98p-pp1 (Complex from dengue virus type 2)
- Human antibody c10 fab (heavy chain) (14 kDa, Protein from Homo sapiens)
- Membrane polyprotein (8 kDa, Protein from dengue virus type 2)
- Human antibody c10 fab (heavy and light chains) (Complex from Homo sapiens)
Structure of rat beta-arrestin 1 by fiducial-assisted cryo-EM
Resolution: 3.52 Å
EM Method: Single-particle
Fitted PDBs: 9dng
Q-score: 0.431
Kahsai AW, Pakharukova N, Kwon HY, Shah KS, Liang-Lin JG, Del Real CT, Shim PJ, Lee MA, Ngo VA, Shreiber BN, Liu S, Schwalb AM, Espinoza EF, Thomas BN, Kunzle CA, Smith JS, Wang J, Kim J, Zhang X, Rockman HA, Thomsen ARB, Rein LAM, Shi L, Ahn S, Masoudi A, Lefkowitz RJ
bioRxiv (2024) [ Pubmed: 39763753 DOI: doi:10.1101/2024.12.27.630464 ]
- Anti-bril fab heavy chain (23 kDa, Protein from Homo sapiens)
- Beta-arrestin-1,soluble cytochrome b562 (55 kDa, Protein from Rattus norvegicus)
- Beta-arrestin 1 with insertion of soluble cytochrome b562 bound to anti-bril fab (Complex from Rattus norvegicus)
- Anti-bril fab light chain (23 kDa, Protein from Homo sapiens)
Structure of rat beta-arrestin 1 bound to allosteric inhibitor
Resolution: 3.47 Å
EM Method: Single-particle
Fitted PDBs: 9dnm
Q-score: 0.466
Kahsai AW, Pakharukova N, Kwon HY, Shah KS, Liang-Lin JG, Del Real CT, Shim PJ, Lee MA, Ngo VA, Shreiber BN, Liu S, Schwalb AM, Espinoza EF, Thomas BN, Kunzle CA, Smith JS, Wang J, Kim J, Zhang X, Rockman HA, Thomsen ARB, Rein LAM, Shi L, Ahn S, Masoudi A, Lefkowitz RJ
bioRxiv (2024) [ Pubmed: 39763753 DOI: doi:10.1101/2024.12.27.630464 ]
- Anti-bril fab heavy chain (23 kDa, Protein from Homo sapiens)
- Beta-arrestin-1,soluble cytochrome b562 (55 kDa, Protein from Rattus norvegicus)
- Anti-bril fab light chain (23 kDa, Protein from Homo sapiens)
- Beta-arrestin 1 with insertion of soluble cytochrome b562 bound to anti-bril fab (Complex from Rattus norvegicus)
- (1beta,6beta,7beta,8alpha,9beta,10alpha,13alpha,14r,16beta)-1,6,7,14-tetrahydroxy-7,20-epoxykauran-15-one (366 Da, Ligand)
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 9c44
Q-score: 0.535
Liu P, Huang ML, Guo H, McCallum M, Si JY, Chen YM, Wang CL, Yu X, Shi LL, Xiong Q, Ma CB, Bowen JE, Tong F, Liu C, Sun YH, Yang X, Chen J, Guo M, Li J, Corti D, Veesler D, Shi ZL, Yan H
Nature (2024) 635 pp. 978-986 [ Pubmed: 39478224 DOI: doi:10.1038/s41586-024-08121-5 ]
- Sars-cov-2 s bound by s2l20 fab (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- S2l20 fab light chain variable region (11 kDa, Protein from Homo sapiens)
- S2l20 fab heavy chain variable (13 kDa, Protein from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 S + S2L20 (local refinement of NTD and S2L20 Fab variable region)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 9c45
Q-score: 0.552
Liu P, Huang ML, Guo H, McCallum M, Si JY, Chen YM, Wang CL, Yu X, Shi LL, Xiong Q, Ma CB, Bowen JE, Tong F, Liu C, Sun YH, Yang X, Chen J, Guo M, Li J, Corti D, Veesler D, Shi ZL, Yan H
Nature (2024) 635 pp. 978-986 [ Pubmed: 39478224 DOI: doi:10.1038/s41586-024-08121-5 ]
- Sars-cov-2 s bound by s2l20 fab (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- S2l20 fab light chain variable region (11 kDa, Protein from Homo sapiens)
- S2l20 fab heavy chain variable (13 kDa, Protein from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 Omicron XBB.1.5 RBD complexed with human ACE2 and S304
Resolution: 2.91 Å
EM Method: Single-particle
Fitted PDBs: 8we4
Q-score: 0.462
Li W, Xu Z, Niu T, Xie Y, Zhao Z, Li D, He Q, Sun W, Shi K, Guo W, Chang Z, Liu K, Fan Z, Qi J, Gao GF
EMBO J (2024) 43 pp. 1484-1498 [ Pubmed: 38467833 DOI: doi:10.1038/s44318-024-00062-z ]
- Zinc ion (65 Da, Ligand)
- Spike protein s1 (25 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- S304 fab light chain (23 kDa, Protein from Homo sapiens)
- Sars-cov-2 omicron xbb.1.5 rbd complexed with human ace2 and fab s304 (Complex)
- Fabs304 (Complex from Homo sapiens)
- Angiotensin-converting enzyme 2 (92 kDa, Protein from Homo sapiens)
- Ace2 (Complex from Homo sapiens)
- S304 fab heavy chain (24 kDa, Protein from Homo sapiens)
- Sars-cov-2 omicron xbb.1.5 rbd (Complex from Severe acute respiratory syndrome coronavirus 2)