SARS-CoV-2 Omicron XBB.1.5 RBD complexed with human ACE2 and S304
Resolution: 2.91 Å
EM Method: Single-particle
Fitted PDBs: 8we4
Q-score: 0.462
Li W, Xu Z, Niu T, Xie Y, Zhao Z, Li D, He Q, Sun W, Shi K, Guo W, Chang Z, Liu K, Fan Z, Qi J, Gao GF
EMBO J (2024) 43 pp. 1484-1498 [ Pubmed: 38467833 DOI: doi:10.1038/s44318-024-00062-z ]
- Ace2 (Complex from Homo sapiens)
- Sars-cov-2 omicron xbb.1.5 rbd complexed with human ace2 and fab s304 (Complex)
- Spike protein s1 (25 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Fabs304 (Complex from Homo sapiens)
- S304 fab heavy chain (24 kDa, Protein from Homo sapiens)
- S304 fab light chain (23 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Sars-cov-2 omicron xbb.1.5 rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- Angiotensin-converting enzyme 2 (92 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of human phagocyte NADPH oxidase in the activated state
Resolution: 2.79 Å
EM Method: Single-particle
Fitted PDBs: 8wej
Q-score: 0.535
Liu X, Shi Y, Liu R, Song K, Chen L
Nature (2024) 627 pp. 189-195 [ Pubmed: 38355798 DOI: doi:10.1038/s41586-024-07056-1 ]
- Neutrophil cytosolic factor 2 (65kda, chronic granulomatous disease, autosomal 2), isoform cra_a (34 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Water (18 Da, Ligand)
- 7d5 fab light chain (26 kDa, Protein from Mus musculus)
- Cytochrome b-245 light chain (21 kDa, Protein from Homo sapiens)
- Dihydroflavine-adenine dinucleotide (787 Da, Ligand)
- Neutrophil cytosol factor 1 (32 kDa, Protein from Homo sapiens)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- 7d5 fab heavy chain (27 kDa, Protein from Mus musculus)
- Cytochrome b-245 heavy chain (65 kDa, Protein from Homo sapiens)
- Rac family small gtpase 1 (21 kDa, Protein from Homo sapiens)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Activated nox2-p22 complex (Complex from Homo sapiens)
Structure of human phagocyte NADPH oxidase in the resting state in the presence of 2 mM NADPH
Resolution: 2.99 Å
EM Method: Single-particle
Fitted PDBs: 8x2l
Q-score: 0.487
Liu X, Shi Y, Liu R, Song K, Chen L
Nature (2024) 627 pp. 189-195 [ Pubmed: 38355798 DOI: doi:10.1038/s41586-024-07056-1 ]
- Magnesium ion (24 Da, Ligand)
- Water (18 Da, Ligand)
- 7d5 fab light chain (26 kDa, Protein from Mus musculus)
- Cytochrome b-245 light chain (21 kDa, Protein from Homo sapiens)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Resting nox2-p22 complex (Complex from Homo sapiens)
- 7d5 fab heavy chain (27 kDa, Protein from Mus musculus)
- Cytochrome b-245 heavy chain (65 kDa, Protein from Homo sapiens)
- Flavin-adenine dinucleotide (785 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Antibody N3-1 bound to RBDs in the up and down conformations
Resolution: 2.79 Å
EM Method: Single-particle
Fitted PDBs: 8tm1
Q-score: 0.543
Goike J, Hsieh CL, Horton AP, Gardner EC, Zhou L, Bartzoka F, Wang N, Javanmardi K, Herbert A, Abbassi S, Xie X, Xia H, Shi PY, Renberg R, Segall-Shapiro TH, Terrace CI, Wu W, Shroff R, Byrom M, Ellington AD, Marcotte EM, Musser JM, Kuchipudi SV, Kapur V, Georgiou G, Weaver SC, Dye JM, Boutz DR, McLellan JS, Gollihar JD
Commun Biol (2023) 6 pp. 1250-1250 [ Pubmed: 38082099 DOI: doi:10.1038/s42003-023-05649-6 ]
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- N3-1 fab heavy chain (14 kDa, Protein from Homo sapiens)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- N3-1 fab light chain (11 kDa, Protein from Homo sapiens)
- N3-1 fab (Complex from Homo sapiens)
- The complex of n3-1 fab bound to two receptor binding domains of the spike (Complex)
Antibody N3-1 bound to RBD in the up conformation
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8tma
Q-score: 0.501
Goike J, Hsieh CL, Horton AP, Gardner EC, Zhou L, Bartzoka F, Wang N, Javanmardi K, Herbert A, Abbassi S, Xie X, Xia H, Shi PY, Renberg R, Segall-Shapiro TH, Terrace CI, Wu W, Shroff R, Byrom M, Ellington AD, Marcotte EM, Musser JM, Kuchipudi SV, Kapur V, Georgiou G, Weaver SC, Dye JM, Boutz DR, McLellan JS, Gollihar JD
Commun Biol (2023) 6 pp. 1250-1250 [ Pubmed: 38082099 DOI: doi:10.1038/s42003-023-05649-6 ]
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- The complex of n3-1 fab bound to one receptor binding domain of the spike (Complex)
- N3-1 fab heavy chain (14 kDa, Protein from Homo sapiens)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- N3-1 fab light chain (11 kDa, Protein from Homo sapiens)
- N3-1 fab (Complex from Homo sapiens)
Structure of a class A GPCR/Fab complex
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8tlm
Q-score: 0.527
Sun D, Sun Y, Janezic E, Zhou T, Johnson M, Azumaya C, Noreng S, Chiu C, Seki A, Arenzana TL, Nicoludis JM, Shi Y, Wang B, Ho H, Joshi P, Tam C, Payandeh J, Comps-Agrar L, Wang J, Rutz S, Koerber JT, Masureel M
Nat Commun (2023) 14 pp. 7940-7940 [ DOI: doi:10.1038/s41467-023-43601-8 Pubmed: 38040762 ]
- Fab heavy chain (23 kDa, Protein from Oryctolagus cuniculus)
- C-c chemokine receptor type 8, green fluorescent protein fusion (76 kDa, Protein from Aequorea victoria)
- Ccr8_fab complex (Complex from Homo sapiens)
- Fab light chain (23 kDa, Protein from Oryctolagus cuniculus)
Cryo-EM Structure of Eastern Equine Encephalitis Virus in complex with SKE26 Fab
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8dwo
Q-score: 0.483
Sutton MS, Pletnev S, Callahan V, Ko S, Tsybovsky Y, Bylund T, Casner RG, Cerutti G, Gardner CL, Guirguis V, Verardi R, Zhang B, Ambrozak D, Beddall M, Lei H, Yang ES, Liu T, Henry AR, Rawi R, Schon A, Schramm CA, Shen CH, Shi W, Stephens T, Yang Y, Florez MB, Ledgerwood JE, Burke CW, Shapiro L, Fox JM, Kwong PD, Roederer M
Cell (2023) 186 pp. 2672-2689.e25 [ Pubmed: 37295404 DOI: doi:10.1016/j.cell.2023.05.019 ]
- Ske26 fab light chain (23 kDa, Protein from Macaca fascicularis)
- Eastern equine encephalitis virus (Virus from Eastern equine encephalitis virus)
- Envelope glycoprotein e1 (47 kDa, Protein from Eastern equine encephalitis virus)
- Envelope glycoprotein e2 (47 kDa, Protein from Eastern equine encephalitis virus)
- Ske26 fab heavy chain (25 kDa, Protein from Macaca fascicularis)
Cryo-EM Structure of Western Equine Encephalitis Virus VLP in complex with SKW19 fab
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 8ded
Q-score: 0.363
Sutton MS, Pletnev S, Callahan V, Ko S, Tsybovsky Y, Bylund T, Casner RG, Cerutti G, Gardner CL, Guirguis V, Verardi R, Zhang B, Ambrozak D, Beddall M, Lei H, Yang ES, Liu T, Henry AR, Rawi R, Schon A, Schramm CA, Shen CH, Shi W, Stephens T, Yang Y, Florez MB, Ledgerwood JE, Burke CW, Shapiro L, Fox JM, Kwong PD, Roederer M
Cell (2023) 186 pp. 2672-2689.e25 [ Pubmed: 37295404 DOI: doi:10.1016/j.cell.2023.05.019 ]
- Skw19 fab light chain (23 kDa, Protein from Homo sapiens)
- Skw19 fab heavy chain (25 kDa, Protein from Homo sapiens)
- Spike glycoprotein e2 (46 kDa, Protein from Western equine encephalitis virus)
- Western equine encephalitis virus (Virus from Western equine encephalitis virus)
- Spike glycoprotein e1 (47 kDa, Protein from Western equine encephalitis virus)
Cryo-EM Structure of Western Equine Encephalitis Virus VLP in complex with SKW24 fab
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 8def
Q-score: 0.302
Sutton MS, Pletnev S, Callahan V, Ko S, Tsybovsky Y, Bylund T, Casner RG, Cerutti G, Gardner CL, Guirguis V, Verardi R, Zhang B, Ambrozak D, Beddall M, Lei H, Yang ES, Liu T, Henry AR, Rawi R, Schon A, Schramm CA, Shen CH, Shi W, Stephens T, Yang Y, Florez MB, Ledgerwood JE, Burke CW, Shapiro L, Fox JM, Kwong PD, Roederer M
Cell (2023) 186 pp. 2672-2689.e25 [ Pubmed: 37295404 DOI: doi:10.1016/j.cell.2023.05.019 ]
- Skw24 fab heavy chain (25 kDa, Protein from Homo sapiens)
- Spike glycoprotein e2 (46 kDa, Protein from Western equine encephalitis virus)
- Western equine encephalitis virus (Virus from Western equine encephalitis virus)
- Skw24 fab light chain (22 kDa, Protein from Homo sapiens)
- Spike glycoprotein e1 (47 kDa, Protein from Western equine encephalitis virus)
Cryo-EM local refinement of antibody SKV09 in complex with VEEV alphavirus spike glycoprotein
Resolution: 6.0 Å
EM Method: Single-particle
Fitted PDBs: 8deq
Q-score: 0.19
Sutton MS, Pletnev S, Callahan V, Ko S, Tsybovsky Y, Bylund T, Casner RG, Cerutti G, Gardner CL, Guirguis V, Verardi R, Zhang B, Ambrozak D, Beddall M, Lei H, Yang ES, Liu T, Henry AR, Rawi R, Schon A, Schramm CA, Shen CH, Shi W, Stephens T, Yang Y, Florez MB, Ledgerwood JE, Burke CW, Shapiro L, Fox JM, Kwong PD, Roederer M
Cell (2023) 186 pp. 2672-2689.e25 [ Pubmed: 37295404 DOI: doi:10.1016/j.cell.2023.05.019 ]
- Cryo-em local refinement of antibody skv09 in complex with veev alphavirus spike glycoprotein (Complex from Venezuelan equine encephalitis virus)
- Skv09 fab heavy chain (13 kDa, Protein from Macaca)
- Spike glycoprotein e1 (43 kDa, Protein from Venezuelan equine encephalitis virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Skv09 fab light chain (11 kDa, Protein from Macaca)