Middle Region of Apolipoprotein B 100 bound to Low Density Lipoprotein Receptor
Resolution: 4.18 Å
EM Method: Single-particle
Fitted PDBs: 9bde
Q-score: 0.311
Reimund M, Dearborn AD, Graziano G, Lei H, Ciancone AM, Kumar A, Holewinski R, Neufeld EB, O'Reilly FJ, Remaley AT, Marcotrigiano J
Nature (2024) [ DOI: doi:10.1038/s41586-024-08223-0 Pubmed: 39663455 ]
- Apob100 nanobody 4 (14 kDa, Protein from Camelus bactrianus)
- Legobody 8d3 fab light chain (24 kDa, Protein from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Legobody 8d3 fab heavy chain (25 kDa, Protein from Mus musculus)
- Calcium ion (40 Da, Ligand)
- Low-density lipoprotein receptor (95 kDa, Protein from Homo sapiens)
- Middle of apob100 bound to ldl receptor and legobody (Complex)
- Apolipoprotein b 100 (516 kDa, Protein from Homo sapiens)
- Maltose/maltodextrin-binding periplasmic protein,immunoglobulin g-binding protein a,immunoglobulin g-binding protein g (59 kDa, Protein from Streptococcus sp. 'group G')
Apolipoprotein B 100 bound to LDL receptor and legobody
Resolution: 5.4 Å
EM Method: Single-particle
Fitted PDBs: 9bdt
Q-score: 0.198
Reimund M, Dearborn AD, Graziano G, Lei H, Ciancone AM, Kumar A, Holewinski R, Neufeld EB, O'Reilly FJ, Remaley AT, Marcotrigiano J
Nature (2024) [ DOI: doi:10.1038/s41586-024-08223-0 Pubmed: 39663455 ]
- Apob100 nanobody 4 (14 kDa, Protein from Camelus bactrianus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Legobody 8d3 fab light chain (24 kDa, Protein from Mus musculus)
- Legobody 8d3 fab heavy chain (25 kDa, Protein from Mus musculus)
- Calcium ion (40 Da, Ligand)
- Low-density lipoprotein receptor (95 kDa, Protein from Homo sapiens)
- Apoliprotein b 100 from ldl bound to ldl receptor and legobody (Complex from Homo sapiens)
- Apolipoprotein b-100 (516 kDa, Protein from Homo sapiens)
- Maltodextrin-binding protein,immunoglobulin g-binding protein a,immunoglobulin g-binding protein g (59 kDa, Protein from Escherichia coli)
Nanobody 4 bound to Apolipoprotein B 100
Resolution: 3.73 Å
EM Method: Single-particle
Fitted PDBs: 9coo
Q-score: 0.396
Reimund M, Dearborn AD, Graziano G, Lei H, Ciancone AM, Kumar A, Holewinski R, Neufeld EB, O'Reilly FJ, Remaley AT, Marcotrigiano J
Nature (2024) [ DOI: doi:10.1038/s41586-024-08223-0 Pubmed: 39663455 ]
- Apob100 nanobody 4 (14 kDa, Protein from Camelus bactrianus)
- Middle of apob100 bound to ldl receptor and legobody (Complex from Homo sapiens)
- Legobody 8d3 fab light chain (24 kDa, Protein from Mus musculus)
- Legobody 8d3 fab heavy chain (25 kDa, Protein from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Low-density lipoprotein receptor (88 kDa, Protein from Homo sapiens)
- Apolipoprotein b 100 (516 kDa, Protein from Homo sapiens)
- Maltodextrin-binding protein,immunoglobulin g-binding protein a,immunoglobulin g-binding protein g (59 kDa, Protein from Escherichia coli)