Resolution: 35.0 Å
EM Method: Single-particle
Fitted PDBs: 6avq
Q-score: 0.045
Borst AJ, James ZM, Zagotta WN, Ginsberg M, Rey FA, DiMaio F, Backovic M, Veesler D
Structure (2017) 25 pp. 1732-1739.e5 [ DOI: doi:10.1016/j.str.2017.09.007 Pubmed: 29033288 ]
- Integrin beta-3 (76 kDa, Protein from Homo sapiens)
- Integrin alpha-v (105 kDa, Protein from Homo sapiens)
- Lm609 fab heavy chain (27 kDa, Protein from Mus musculus)
- Lm609 fab light chain (23 kDa, Protein from Mus musculus)
- Quaternary complex of human alpha-v beta-3 integrin with the fab lm609 (230 kDa, Complex from Homo sapiens)
CH505 SOSIP.664 trimer in complex with DH522.2 Fab
Williams WB, Zhang J, Jiang C, Nicely NI, Fera D, Luo K, Moody MA, Liao HX, Alam SM, Kepler TB, Ramesh A, Wiehe K, Holland JA, Bradley T, Vandergrift N, Saunders KO, Parks R, Foulger A, Xia SM, Bonsignori M, Montefiori DC, Louder M, Eaton A, Santra S, Scearce R, Sutherland L, Newman A, Bouton-Verville H, Bowman C, Bomze H, Gao F, Marshall DJ, Whitesides JF, Nie X, Kelsoe G, Reed SG, Fox CB, Clary K, Koutsoukos M, Franco D, Mascola JR, Harrison SC, Haynes BF, Verkoczy L
Nat Commun (2017) 8 pp. 1732-1732 [ Pubmed: 29170366 DOI: doi:10.1038/s41467-017-01336-3 ]
- Ch505 sosip.664 in complex with dh522.2 fab (Complex)
- Ch505 sosip.664 (Macromolecule from Human immunodeficiency virus 1)
- Dh522.2 fab (Complex from Homo sapiens)
- Ch505 sosip.664 (Complex from Homo sapiens)
- Dh522.2 fab light chain (Macromolecule from Homo sapiens)
- Dh522.2 fab heavy chain (Macromolecule from Homo sapiens)
Easterhoff D, Moody MA, Fera D, Cheng H, Ackerman M, Wiehe K, Saunders KO, Pollara J, Vandergrift N, Parks R, Kim J, Michael NL, O'Connell RJ, Excler JL, Robb ML, Vasan S, Rerks-Ngarm S, Kaewkungwal J, Pitisuttithum P, Nitayaphan S, Sinangil F, Tartaglia J, Phogat S, Kepler TB, Alam SM, Liao HX, Ferrari G, Seaman MS, Montefiori DC, Tomaras GD, Harrison SC, Haynes BF
PLoS Pathog (2017) 13 pp. e1006182-e1006182 [ DOI: doi:10.1371/journal.ppat.1006182 Pubmed: 28235027 ]
- Dh576 fab (Complex from Homo sapiens)
- Dh576 fab light chain (Protein from Homo sapiens)
- Ch505 transmitted founder envelope (Complex from Homo sapiens)
- Hiv envelope (Protein from Homo sapiens)
- Dh576 fab heavy chain (Protein from Homo sapiens)
- Hiv-1 ch505 transmitted founder sosip.664 env trimer in complex with the dh576 fab from the rv305 trial (50 kDa, Complex from Homo sapiens)
Pre-fusion structure of trimeric HIV-1 envelope glycoprotein determined by cryo-electron microscopy
Resolution: 6.0 Å
EM Method: Single-particle
Fitted PDBs: 4cc8
Q-score: 0.083
Bartesaghi A, Merk A, Borgnia MJ, Milne JLS, Subramaniam S
Nat Struct Mol Biol (2013) 20 pp. 1352-1357 [ DOI: doi:10.1038/nsmb.2711 Pubmed: 24154805 ]
- Gp120 (Protein from Human immunodeficiency virus 1)
- Monoclonal antibody vrc03 fab light chain (25 kDa, Protein from Homo sapiens)
- Complex of knh1144 sosip gp140 trimer with vrc03 fab. (670 kDa, Sample)
- Gp41 (Protein from Human immunodeficiency virus 1)
- Monoclonal antibody vrc03 fab heavy chain (25 kDa, Protein from Homo sapiens)