Apolipoprotein B 100 bound to LDL receptor and legobody
Resolution: 5.4 Å
EM Method: Single-particle
Fitted PDBs: 9bdt
Q-score: 0.198
Reimund M, Dearborn AD, Graziano G, Lei H, Ciancone AM, Kumar A, Holewinski R, Neufeld EB, O'Reilly FJ, Remaley AT, Marcotrigiano J
Nature (2024) [ DOI: doi:10.1038/s41586-024-08223-0 Pubmed: 39663455 ]
- Apob100 nanobody 4 (14 kDa, Protein from Camelus bactrianus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Legobody 8d3 fab light chain (24 kDa, Protein from Mus musculus)
- Legobody 8d3 fab heavy chain (25 kDa, Protein from Mus musculus)
- Calcium ion (40 Da, Ligand)
- Low-density lipoprotein receptor (95 kDa, Protein from Homo sapiens)
- Apoliprotein b 100 from ldl bound to ldl receptor and legobody (Complex from Homo sapiens)
- Apolipoprotein b-100 (516 kDa, Protein from Homo sapiens)
- Maltodextrin-binding protein,immunoglobulin g-binding protein a,immunoglobulin g-binding protein g (59 kDa, Protein from Escherichia coli)
CCHFV GP38 bound with ADI-46143 and ADI-46158 Fabs
Shin OS, Monticelli SR, Hjorth CK, Hornet V, Doyle M, Abelson D, Kuehne AI, Wang A, Bakken RR, Mishra AK, Middlecamp M, Champney E, Stuart L, Maurer DP, Li J, Berrigan J, Barajas J, Balinandi S, Lutwama JJ, Lobel L, Zeitlin L, Walker LM, Dye JM, Chandran K, Herbert AS, Pauli NT, McLellan JS
Cell Rep (2024) 43 pp. 114502-114502 [ Pubmed: 39002130 DOI: doi:10.1016/j.celrep.2024.114502 ]
- Cchfv gp38 bound with adi-46143 fab and adi-46158 fab (Complex)
- Adi-46158 fab light chain (Protein from Homo sapiens)
- Adi-46143 fab (Complex from Homo sapiens)
- Adi-46143 fab heavy chain (Protein from Homo sapiens)
- Cchfv gp38 (Protein from Crimean-Congo hemorrhagic fever virus)
- Adi-46143 fab light chain (Protein from Homo sapiens)
- Adi-46158 fab heavy chain (Protein from Homo sapiens)
- Cchfv gp38 (Complex from Crimean-Congo hemorrhagic fever virus)
- Adi-46158 fab (Complex from Homo sapiens)
CCHFV GP38 bound with ADI-58062 and ADI-63530 Fabs
Shin OS, Monticelli SR, Hjorth CK, Hornet V, Doyle M, Abelson D, Kuehne AI, Wang A, Bakken RR, Mishra AK, Middlecamp M, Champney E, Stuart L, Maurer DP, Li J, Berrigan J, Barajas J, Balinandi S, Lutwama JJ, Lobel L, Zeitlin L, Walker LM, Dye JM, Chandran K, Herbert AS, Pauli NT, McLellan JS
Cell Rep (2024) 43 pp. 114502-114502 [ Pubmed: 39002130 DOI: doi:10.1016/j.celrep.2024.114502 ]
- Cchfv gp38 bound with adi-58062 fab and adi-63530 fab (Complex)
- Adi-63530 fab (Complex from Homo sapiens)
- Adi-63530 fab light chain (Protein from Homo sapiens)
- Adi-63530 fab heavy chain (Protein from Homo sapiens)
- Cchfv gp38 (Protein from Crimean-Congo hemorrhagic fever virus)
- Adi-58062 fab heavy chain (Protein from Homo sapiens)
- Cchfv gp38 (Complex from Crimean-Congo hemorrhagic fever virus)
- Adi-58062 fab light chain (Protein from Homo sapiens)
- Adi-58062 fab (Complex from Homo sapiens)
Resolution: 5.3 Å
EM Method: Single-particle
Fitted PDBs: 8u5b
Q-score: 0.273
Erramilli SK, Dominik PK, Ogbu CP, Kossiakoff AA, Vecchio AJ
Commun Biol (2024) 7 pp. 733-733 [ DOI: doi:10.1038/s42003-024-06437-6 Pubmed: 38886509 ]
- Heat-labile enterotoxin b chain (14 kDa, Protein from Clostridium perfringens)
- Lauryl maltose neopentyl glycol (1 kDa, Ligand)
- Human claudin-4 complex with clostridium perfringens enterotoxin c-terminal domain and sfab cop-1 (100 kDa, Complex from Homo sapiens)
- Claudin-4 (22 kDa, Protein from Homo sapiens)
- Cop-1 sfab heavy chain (28 kDa, Protein from synthetic construct)
- Cop-1 sfab light chain (23 kDa, Protein from synthetic construct)
To Be Published
- Dh1285 fab light chain (Macromolecule from Macaca mulatta)
- Ch505tfchim.6r.sosip.664.v4.1 env trimer (Macromolecule from Human immunodeficiency virus 1)
- Dh1285 fab heavy chain (Macromolecule from Macaca mulatta)
- Vaccine elicited antibody dh1285 fab bound to ch505tfchim.6r.sosip.664.v4.1. trimer, 2-fab-bound configuration (308 kDa, Cellular component from Homo sapiens)
Resolution: 5.9 Å
EM Method: Single-particle
Fitted PDBs: 7v0n
Q-score: 0.123
Williamson LE, Bandyopadhyay A, Bailey K, Sirohi D, Klose T, Julander JG, Kuhn RJ, Crowe Jr JE
PNAS (2023) 120 pp. e2213690120-e2213690120 [ DOI: doi:10.1073/pnas.2213690120 Pubmed: 36961925 ]
- Spike glycoprotein e1 (43 kDa, Protein from Eastern equine encephalitis virus)
- Igg 21 fab heavy chain (20 kDa, Protein from Homo sapiens)
- Spike glycoprotein e2 (38 kDa, Protein from Eastern equine encephalitis virus)
- Eastern equine encephalitis virus (Virus from Eastern equine encephalitis virus)
- Igg 21 fab light chain (18 kDa, Protein from Homo sapiens)
Resolution: 5.2 Å
EM Method: Single-particle
Fitted PDBs: 7v0p
Q-score: 0.17
Williamson LE, Bandyopadhyay A, Bailey K, Sirohi D, Klose T, Julander JG, Kuhn RJ, Crowe Jr JE
PNAS (2023) 120 pp. e2213690120-e2213690120 [ DOI: doi:10.1073/pnas.2213690120 Pubmed: 36961925 ]
- Igg 106 fab heavy chain (19 kDa, Protein from Homo sapiens)
- Spike glycoprotein e1 (43 kDa, Protein from Eastern equine encephalitis virus)
- Igg 106 fab light chain (18 kDa, Protein from Homo sapiens)
- Spike glycoprotein e2 (38 kDa, Protein from Eastern equine encephalitis virus)
- Eastern equine encephalitis virus (Virus from Eastern equine encephalitis virus)
H1 Solomon Islands 2006 hemagglutinin in complex with Ab111
Caradonna TM, Ronsard L, Yousif AS, Windsor IW, Hecht R, Bracamonte-Moreno T, Roffler AA, Maron MJ, Maurer DP, Feldman J, Marchiori E, Barnes RM, Rohrer D, Lonberg N, Sempowski GD, Kepler TB, Kuraoka M, Lingwood D, Schmidt AG
Cell Rep (2022) 41 pp. 111628-111628 [ DOI: doi:10.1016/j.celrep.2022.111628 Pubmed: 36351401 ]
Cryo-EM structure of full-length human immunoglobulin M - F(ab')2 conformation 1
Resolution: 5.2 Å
EM Method: Single-particle
Fitted PDBs: 8ady
Q-score: 0.122
Chen Q, Menon R, Calder LJ, Tolar P, Rosenthal PB
Nat Commun (2022) 13 pp. 6314-6314 [ Pubmed: 36274064 DOI: doi:10.1038/s41467-022-34090-2 ]
- Full-length human igm pentamer (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Igm fab, light chain (23 kDa, Protein from Homo sapiens)
- Igm fab, heavy chain (24 kDa, Protein from Homo sapiens)
- Immunoglobulin heavy constant mu (41 kDa, Protein from Homo sapiens)
- Igm c2-domain from mouse (12 kDa, Protein from Homo sapiens)
- Immunoglobulin j chain (15 kDa, Protein from Homo sapiens)
Callaway HM, Zyla D, Larrous F, de Melo GD, Hastie KM, Avalos RD, Agarwal A, Corti D, Bourhy H, Saphire EO
Sci Adv (2022) 8 pp. eabp9151-eabp9151 [ Pubmed: 35714192 DOI: doi:10.1126/sciadv.abp9151 ]