Cryo-EM structure of the SFV009 3G01 Fab in complex with A/California/04/2009
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 9dm0
Q-score: 0.511
Lin TH, Lee CD, Fernandez-Quintero ML, Ferguson JA, Han J, Zhu X, Yu W, Guthmiller JJ, Krammer F, Wilson PC, Ward AB, Wilson IA
Nat Commun (2025) 16 pp. 1268-1268 [ DOI: doi:10.1038/s41467-025-56496-4 Pubmed: 39894881 ]
- Hemagglutinin ca09 homotrimer bound to anchor fab (Complex from Homo sapiens)
- Hemagglutinin ha1/2 (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Fab heavy chain (13 kDa, Protein from Homo sapiens)
- Fab light chain (11 kDa, Protein from Homo sapiens)
- Hemagglutinin (26 kDa, Protein from Influenza A virus (A/California/04/2009(H1N1)))
- Fab (Complex)
- Hemagglutinin (35 kDa, Protein from Influenza A virus (A/California/04/2009(H1N1)))
Integrin alpha-5 beta-1 in complex with BIIG2 Fab
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 9b9j
Q-score: 0.589
Nguyen A, Heim JB, Cordara G, Chan MC, Johannesen H, Charlesworth C, Li M, Azumaya CM, Madden B, Krengel U, Meves A, Campbell MG
bioRxiv (2025) [ DOI: doi:10.1101/2025.01.08.631572 Pubmed: 39829743 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Biig2 fab light chain (23 kDa, Protein from Rattus norvegicus)
- Calcium ion (40 Da, Ligand)
- Protein complex of integrin alpha-5 beta-1 with biig2 fab (Complex from Homo sapiens)
- Integrin alpha-5 light chain (108 kDa, Protein from Homo sapiens)
- Biig2 fab heavy chain (23 kDa, Protein from Rattus norvegicus)
- Integrin beta-1 (80 kDa, Protein from Homo sapiens)
Integrin alpha-5 beta-1 in complex with MINT1526A Fab
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 9b9k
Q-score: 0.547
Nguyen A, Heim JB, Cordara G, Chan MC, Johannesen H, Charlesworth C, Li M, Azumaya CM, Madden B, Krengel U, Meves A, Campbell MG
bioRxiv (2025) [ DOI: doi:10.1101/2025.01.08.631572 Pubmed: 39829743 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Protein complex of integrin alpha-5 beta-1 with mint1526a fab (Complex from Homo sapiens)
- Integrin alpha-5 light chain (108 kDa, Protein from Homo sapiens)
- Mint1526a fab heavy chain (13 kDa, Protein from unidentified)
- Mint1526a fab light chain (11 kDa, Protein from unidentified)
- Integrin beta-1 (80 kDa, Protein from Homo sapiens)
Structure of rat beta-arrestin 1 by fiducial-assisted cryo-EM
Resolution: 3.52 Å
EM Method: Single-particle
Fitted PDBs: 9dng
Q-score: 0.431
Kahsai AW, Pakharukova N, Kwon HY, Shah KS, Liang-Lin JG, Del Real CT, Shim PJ, Lee MA, Ngo VA, Shreiber BN, Liu S, Schwalb AM, Espinoza EF, Thomas BN, Kunzle CA, Smith JS, Wang J, Kim J, Zhang X, Rockman HA, Thomsen ARB, Rein LAM, Shi L, Ahn S, Masoudi A, Lefkowitz RJ
bioRxiv (2024) [ Pubmed: 39763753 DOI: doi:10.1101/2024.12.27.630464 ]
- Anti-bril fab heavy chain (23 kDa, Protein from Homo sapiens)
- Beta-arrestin-1,soluble cytochrome b562 (55 kDa, Protein from Rattus norvegicus)
- Beta-arrestin 1 with insertion of soluble cytochrome b562 bound to anti-bril fab (Complex from Rattus norvegicus)
- Anti-bril fab light chain (23 kDa, Protein from Homo sapiens)
Structure of rat beta-arrestin 1 bound to allosteric inhibitor
Resolution: 3.47 Å
EM Method: Single-particle
Fitted PDBs: 9dnm
Q-score: 0.466
Kahsai AW, Pakharukova N, Kwon HY, Shah KS, Liang-Lin JG, Del Real CT, Shim PJ, Lee MA, Ngo VA, Shreiber BN, Liu S, Schwalb AM, Espinoza EF, Thomas BN, Kunzle CA, Smith JS, Wang J, Kim J, Zhang X, Rockman HA, Thomsen ARB, Rein LAM, Shi L, Ahn S, Masoudi A, Lefkowitz RJ
bioRxiv (2024) [ Pubmed: 39763753 DOI: doi:10.1101/2024.12.27.630464 ]
- Anti-bril fab heavy chain (23 kDa, Protein from Homo sapiens)
- Beta-arrestin-1,soluble cytochrome b562 (55 kDa, Protein from Rattus norvegicus)
- Anti-bril fab light chain (23 kDa, Protein from Homo sapiens)
- Beta-arrestin 1 with insertion of soluble cytochrome b562 bound to anti-bril fab (Complex from Rattus norvegicus)
- (1beta,6beta,7beta,8alpha,9beta,10alpha,13alpha,14r,16beta)-1,6,7,14-tetrahydroxy-7,20-epoxykauran-15-one (366 Da, Ligand)
SFTSV Gn in complex with JK-8/12 Fab
Resolution: 2.37 Å
EM Method: Single-particle
Fitted PDBs: 8zhq
Q-score: 0.505
Zhang S, Shang H, Han S, Li J, Peng X, Wu Y, Yang X, Leng Y, Wang F, Cui N, Xu L, Zhang H, Guo Y, Xu X, Zhang N, Liu W, Li H
Ebiomedicine (2024) 111 pp. 105481-105481 [ Pubmed: 39644769 DOI: doi:10.1016/j.ebiom.2024.105481 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Jk-8 fab light chain (23 kDa, Protein from Homo sapiens)
- Jk-8 fab heavy chain (23 kDa, Protein from Homo sapiens)
- Jk-12 fab heavy chain (22 kDa, Protein from Homo sapiens)
- Jk-12 fab light chain (22 kDa, Protein from Homo sapiens)
- Ternary complex of sftsv gn with neutralizing antibodies fab jk-8 and jk-12 (150 kDa, Complex from Homo sapiens)
- Envelopment polyprotein (38 kDa, Protein from Severe fever with thrombocytopenia syndrome virus)
Cryo-EM structure of hemagglutinin H5 A/Texas/37/2024 in complex with LSTa and antibody CR9114
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 9dwe
Q-score: 0.559
Good MR, Fernandez-Quintero ML, Ji W, Rodriguez AJ, Han J, Ward AB, Guthmiller JJ
Nat Commun (2024) 15 pp. 10768-10768 [ DOI: doi:10.1038/s41467-024-54934-3 Pubmed: 39737954 ]
- Hemagglutinin (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Hemagglutinin h5 a/texas/37/2024 homotrimer bound to lsta and cr9114 fab (Complex from Homo sapiens)
- Cr9114 fab fab heavy chain (12 kDa, Protein from Homo sapiens)
- Hemagglutinin (65 kDa, Protein from Influenza A virus)
- Cr9114 fab (Complex from Homo sapiens)
- Cr9114 fab light chain (11 kDa, Protein from Homo sapiens)
Macaca fascicularis NTCP in complex with YN69083 Fab
Resolution: 3.49 Å
EM Method: Single-particle
Fitted PDBs: 8xcd
Q-score: 0.368
Shionoya K, Park JH, Ekimoto T, Takeuchi JS, Mifune J, Morita T, Ishimoto N, Umezawa H, Yamamoto K, Kobayashi C, Kusunoki A, Nomura N, Iwata S, Muramatsu M, Tame JRH, Ikeguchi M, Park SY, Watashi K
Nat Commun (2024) 15 pp. 9241-9241 [ DOI: doi:10.1038/s41467-024-53533-6 Pubmed: 39455604 ]
- Yn69083 fab heavy chain (27 kDa, Protein from Mus musculus)
- Solute carrier family 10 member a1 (38 kDa, Protein from Macaca fascicularis)
- Taurocholic acid (515 Da, Ligand)
- Macaca fascicularis ntcp in complex with yn69083 fab (89 kDa, Complex from Macaca fascicularis)
- Yn69083 fab light chain (23 kDa, Protein from Mus musculus)
Structure of the semi-extended AlphaIIbBeta3 in complex with R21D10 Fab
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 9axl
Q-score: 0.473
Wang L, Wang J, Li J, Walz T, Coller BS
Blood Adv (2024) 8 pp. 4398-4409 [ DOI: doi:10.1182/bloodadvances.2024013177 Pubmed: 38968144 ]
- Calcium ion (40 Da, Ligand)
- Integrin beta-3 (87 kDa, Protein from Homo sapiens)
- Integrin alpha-iib (113 kDa, Protein from Homo sapiens)
- The semi-extended alphaiibbeta3 in complex with r21d10 fab (250 kDa, Complex)
- Magnesium ion (24 Da, Ligand)
- R21d10 fab light chain (23 kDa, Protein from Mus musculus)
- R21d10 fab heavy chain (24 kDa, Protein from Mus musculus)
- Water (18 Da, Ligand)
The map of the bent AlphaIIbBeta3 in complex with R21D10 Fab
Wang L, Wang J, Li J, Walz T, Coller BS
Blood Adv (2024) 8 pp. 4398-4409 [ DOI: doi:10.1182/bloodadvances.2024013177 Pubmed: 38968144 ]
- Integrin alphaiib (Protein from Homo sapiens)
- Alphaiibbeta3 integrin (Complex from Homo sapiens)
- Integrin beta3 (Protein from Homo sapiens)
- R21d10 fab (Complex from Mus musculus)
- R211010 fab light chain (Protein from Mus musculus)
- The semi-extended alphaiibbeta3 in complex with r21d10 fab (250 kDa, Complex)
- R21d10 fab heavy chain (Protein from Mus musculus)