Venezuelan equine encephalitis virus-like particle in complex with Fab SKT05
Sutton MS, Pletnev S, Callahan V, Ko S, Tsybovsky Y, Bylund T, Casner RG, Cerutti G, Gardner CL, Guirguis V, Verardi R, Zhang B, Ambrozak D, Beddall M, Lei H, Yang ES, Liu T, Henry AR, Rawi R, Schon A, Schramm CA, Shen CH, Shi W, Stephens T, Yang Y, Florez MB, Ledgerwood JE, Burke CW, Shapiro L, Fox JM, Kwong PD, Roederer M
Cell (2023) 186 pp. 2672-2689.e25 [ DOI: doi:10.1016/j.cell.2023.05.019 Pubmed: 37295404 ]
- Fab skt05 light chain (Protein from Macaca fascicularis)
- Coat protein (Protein from Venezuelan equine encephalitis virus)
- Fab skt05 heavy chain (Protein from Macaca fascicularis)
- Complex between venezuelan equine encephalitis virus-like particle and fab skt05 (33 MDa, Complex from Venezuelan equine encephalitis virus)
Venezuelan equine encephalitis virus-like particle in complex with Fab SKT05, local refinement
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8eeu
Q-score: 0.462
Sutton MS, Pletnev S, Callahan V, Ko S, Tsybovsky Y, Bylund T, Casner RG, Cerutti G, Gardner CL, Guirguis V, Verardi R, Zhang B, Ambrozak D, Beddall M, Lei H, Yang ES, Liu T, Henry AR, Rawi R, Schon A, Schramm CA, Shen CH, Shi W, Stephens T, Yang Y, Florez MB, Ledgerwood JE, Burke CW, Shapiro L, Fox JM, Kwong PD, Roederer M
Cell (2023) 186 pp. 2672-2689.e25 [ DOI: doi:10.1016/j.cell.2023.05.019 Pubmed: 37295404 ]
- Coat protein (138 kDa, Protein from Venezuelan equine encephalitis virus)
- Fab skt05 light chain (23 kDa, Protein from Macaca fascicularis)
- Fab skt05 heavy chain (25 kDa, Protein from Macaca fascicularis)
- Complex between venezuelan equine encephalitis virus-like particle and fab skt05 (33 MDa, Complex from Venezuelan equine encephalitis virus)
Resolution: 4.17 Å
EM Method: Single-particle
Fitted PDBs: 8dul
Q-score: 0.241
Sutton MS, Pletnev S, Callahan V, Ko S, Tsybovsky Y, Bylund T, Casner RG, Cerutti G, Gardner CL, Guirguis V, Verardi R, Zhang B, Ambrozak D, Beddall M, Lei H, Yang ES, Liu T, Henry AR, Rawi R, Schon A, Schramm CA, Shen CH, Shi W, Stephens T, Yang Y, Florez MB, Ledgerwood JE, Burke CW, Shapiro L, Fox JM, Kwong PD, Roederer M
Cell (2023) 186 pp. 2672-2689.e25 [ DOI: doi:10.1016/j.cell.2023.05.019 Pubmed: 37295404 ]
- Antibody fab skt05 light chain (23 kDa, Protein from Macaca fascicularis)
- Western equine encephalitis virus trimer in complex with antibody fab skt05 (Complex from Western equine encephalitis virus)
- Spike glycoprotein e2 (45 kDa, Protein from Western equine encephalitis virus)
- Antibody fab skt05 heavy chain (25 kDa, Protein from Macaca fascicularis)
- Spike glycoprotein e1 (52 kDa, Protein from Western equine encephalitis virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)