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sample_name:"Fab-B heavy chain"
SARS-CoV-2 M protein dimer in complex with JNJ-9676 and Fab-B
To Be Published
Sample:
- (6s,8r)-n-(3-cyanophenyl)-5-{4-[difluoro(phenyl)methyl]phenyl}-6-methyl-4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-3-carboxamide (497 Da, Ligand)
- Dimer complex of sars-cov-2 m protein with jnj-9676 and fab b (Complex from Homo sapiens)
- Fab b heavy chain (24 kDa, Protein from Homo sapiens)
- Fab b light chain (24 kDa, Protein from Homo sapiens)
- Membrane protein (29 kDa, Protein from SARS-CoV-2 pseudovirus)
SARS-CoV-2 M protein dimer (short form) in complex with Fab-B and CIM-834
Release date: Jan. 22, 2025
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 9exa
Q-score: 0.503
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 9exa
Q-score: 0.503
Laporte M, Jochmans D, Bardiot D, Desmarets L, Debski-Antoniak OJ, Mizzon G, Abdelnabi R, Leyssen P, Chiu W, Zhang Z, Nomura N, Bolland S, Ohto U, Stahl Y, Wuyts J, De Jonghe S, Dubuisson J, Bosch BJ, van Kuppeveld JM, Eydoux C, Decroly E, Canard B, Naesens L, Snijder E, Belouzard S, Shimizu T, Bartenschlager R, Hurdiss DL, Marchand A, Chaltin P, Neyts J
To Be Published
Sample:
- Membrane protein (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 m protein dimer (short form) in complex with fab-b and cim-834 (154 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- 6-[[1-[4,6-dimethyl-5-(2-methylpropyl)pyrimidin-2-yl]piperidin-4-yl]-methyl-amino]-n-(2-pyrrolidin-1-ylethyl)pyridazine-4-carboxamide (494 Da, Ligand)
- Fab-b heavy chain (22 kDa, Protein from Mus musculus)
- Fab-b light chain (23 kDa, Protein from Mus musculus)