Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8prv
Q-score: 0.581
Singh K, Bunzel G, Graf B, Yip KM, Neumann-Schaal M, Stark H, Chari A
Cell (2023) 186 pp. 5054-5067.e16 [ Pubmed: 37949058 DOI: doi:10.1016/j.cell.2023.10.009 ]
- Fatty acid synthase subunit beta (229 kDa, Protein from Saccharomyces cerevisiae)
- Yeast fatty acid synthase (Complex from Saccharomyces cerevisiae)
- ~{s}-[2-[3-[[(2~{r})-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl] 3-oxidanylidenebutanethioate (442 Da, Ligand)
- Fatty acid synthase subunit alpha (207 kDa, Protein from Saccharomyces cerevisiae)
- Flavin mononucleotide (456 Da, Ligand)
- Coenzyme a (767 Da, Ligand)
- Nadp nicotinamide-adenine-dinucleotide phosphate (743 Da, Ligand)
Cryo-EM structure of the yeast fatty acid synthase at 1.9 angstrom resolution
Resolution: 1.9 Å
EM Method: Single-particle
Fitted PDBs: 8prw
Q-score: 0.712
Singh K, Bunzel G, Graf B, Yip KM, Neumann-Schaal M, Stark H, Chari A
Cell (2023) 186 pp. 5054-5067.e16 [ Pubmed: 37949058 DOI: doi:10.1016/j.cell.2023.10.009 ]
- Fatty acid synthase subunit beta (229 kDa, Protein from Saccharomyces cerevisiae)
- Yeast fatty acid synthase (Complex from Saccharomyces cerevisiae)
- 1-deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydro-2h-benzo[g]pteridin-1-id-10(5h)-yl)-5-o-phosphonato-d-ribitol (458 Da, Ligand)
- Water (18 Da, Ligand)
- Fatty acid synthase subunit alpha (207 kDa, Protein from Saccharomyces cerevisiae)
- Coenzyme a (767 Da, Ligand)
- Nadp nicotinamide-adenine-dinucleotide phosphate (743 Da, Ligand)
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8ps1
Q-score: 0.588
Singh K, Bunzel G, Graf B, Yip KM, Neumann-Schaal M, Stark H, Chari A
Cell (2023) 186 pp. 5054-5067.e16 [ Pubmed: 37949058 DOI: doi:10.1016/j.cell.2023.10.009 ]
- Fatty acid synthase subunit beta (229 kDa, Protein from Saccharomyces cerevisiae)
- Yeast fatty acid synthase (Complex from Saccharomyces cerevisiae)
- Fatty acid synthase subunit alpha (207 kDa, Protein from Saccharomyces cerevisiae)
- Flavin mononucleotide (456 Da, Ligand)
- Coenzyme a (767 Da, Ligand)
- Nadp nicotinamide-adenine-dinucleotide phosphate (743 Da, Ligand)
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8ps2
Q-score: 0.575
Singh K, Bunzel G, Graf B, Yip KM, Neumann-Schaal M, Stark H, Chari A
Cell (2023) 186 pp. 5054-5067.e16 [ Pubmed: 37949058 DOI: doi:10.1016/j.cell.2023.10.009 ]
- Fatty acid synthase subunit beta (228 kDa, Protein from Saccharomyces cerevisiae)
- Yeast fatty acid synthase (Complex from Saccharomyces cerevisiae)
- Fatty acid synthase subunit alpha (207 kDa, Protein from Saccharomyces cerevisiae)
- Flavin mononucleotide (456 Da, Ligand)
- Malonyl-coenzyme a (853 Da, Ligand)
- ~{s}-[2-[3-[[(2~{r})-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl] (~{e})-but-2-enethioate (426 Da, Ligand)
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8ps9
Q-score: 0.574
Singh K, Bunzel G, Graf B, Yip KM, Neumann-Schaal M, Stark H, Chari A
Cell (2023) 186 pp. 5054-5067.e16 [ DOI: doi:10.1016/j.cell.2023.10.009 Pubmed: 37949058 ]
- Flavin mononucleotide (456 Da, Ligand)
- Malonyl-coenzyme a (853 Da, Ligand)
- Fatty acid synthase subunit beta (228 kDa, Protein from Saccharomyces cerevisiae)
- Fatty acid synthase subunit alpha (207 kDa, Protein from Saccharomyces cerevisiae)
- Yeast fatty acid synthase (Complex from Saccharomyces cerevisiae)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8psa
Q-score: 0.423
Singh K, Bunzel G, Graf B, Yip KM, Neumann-Schaal M, Stark H, Chari A
Cell (2023) 186 pp. 5054-5067.e16 [ Pubmed: 37949058 DOI: doi:10.1016/j.cell.2023.10.009 ]
- Flavin mononucleotide (456 Da, Ligand)
- Fatty acid synthase subunit beta (228 kDa, Protein from Saccharomyces cerevisiae)
- Yeast fatty acid synthase (Complex from Saccharomyces cerevisiae)
- Fatty acid synthase subunit alpha (207 kDa, Protein from Saccharomyces cerevisiae)
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8psf
Q-score: 0.541
Singh K, Bunzel G, Graf B, Yip KM, Neumann-Schaal M, Stark H, Chari A
Cell (2023) 186 pp. 5054-5067.e16 [ Pubmed: 37949058 DOI: doi:10.1016/j.cell.2023.10.009 ]
- Fatty acid synthase subunit beta (228 kDa, Protein from Saccharomyces cerevisiae)
- Yeast fatty acid synthase (Complex from Saccharomyces cerevisiae)
- Fatty acid synthase subunit alpha (207 kDa, Protein from Saccharomyces cerevisiae)
- 4'-phosphopantetheine (358 Da, Ligand)
- Flavin mononucleotide (456 Da, Ligand)
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8psg
Q-score: 0.407
Singh K, Bunzel G, Graf B, Yip KM, Neumann-Schaal M, Stark H, Chari A
Cell (2023) 186 pp. 5054-5067.e16 [ Pubmed: 37949058 DOI: doi:10.1016/j.cell.2023.10.009 ]
- Flavin mononucleotide (456 Da, Ligand)
- Fatty acid synthase subunit beta (228 kDa, Protein from Saccharomyces cerevisiae)
- Yeast fatty acid synthase (Complex from Saccharomyces cerevisiae)
- Fatty acid synthase subunit alpha (207 kDa, Protein from Saccharomyces cerevisiae)
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8psj
Q-score: 0.446
Singh K, Bunzel G, Graf B, Yip KM, Neumann-Schaal M, Stark H, Chari A
Cell (2023) 186 pp. 5054-5067.e16 [ DOI: doi:10.1016/j.cell.2023.10.009 Pubmed: 37949058 ]
- Flavin mononucleotide (456 Da, Ligand)
- Fatty acid synthase subunit beta (228 kDa, Protein from Saccharomyces cerevisiae)
- Fatty acid synthase subunit alpha (207 kDa, Protein from Saccharomyces cerevisiae)
- Yeast fatty acid synthase (Complex from Saccharomyces cerevisiae)
- 4'-phosphopantetheine (358 Da, Ligand)
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8psk
Q-score: 0.578
Singh K, Bunzel G, Graf B, Yip KM, Neumann-Schaal M, Stark H, Chari A
Cell (2023) 186 pp. 5054-5067.e16 [ Pubmed: 37949058 DOI: doi:10.1016/j.cell.2023.10.009 ]
- Flavin mononucleotide (456 Da, Ligand)
- Fatty acid synthase subunit beta (228 kDa, Protein from Saccharomyces cerevisiae)
- Yeast fatty acid synthase (Complex from Saccharomyces cerevisiae)
- Fatty acid synthase subunit alpha (207 kDa, Protein from Saccharomyces cerevisiae)