Structure of C. albicans FAS in in an inhibited state.
Resolution: 2.66 Å
EM Method: Single-particle
Fitted PDBs: 7tui
Q-score: 0.413
Not published () [ ]
- Fatty acid synthase (2 MDa, Complex from Candida albicans)
- Fatty acid synthase subunit alpha (207 kDa, Protein from Candida albicans)
- Fatty acid synthase subunit beta (228 kDa, Protein from Candida albicans)
- Flavin mononucleotide (456 Da, Ligand)
Electron cryomicroscopy Structure of S. cerevisiae FAS in the Apo state
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 6u5t
Q-score: 0.442
Lou JW, Iyer KR, Hasan SMN, Cowen LE, Mazhab-Jafari MT
Sci Rep (2019) 9 pp. 12987-12987 [ DOI: doi:10.1038/s41598-019-49261-3 Pubmed: 31506493 ]
- Flavin mononucleotide (456 Da, Ligand)
- Fatty acid synthase (2 MDa, Complex from Saccharomyces cerevisiae)
- Fatty acid synthase subunit beta (231 kDa, Protein from Baker's yeast)
- Fatty acid synthase subunit alpha (207 kDa, Protein from Baker's yeast)
- 4'-phosphopantetheine (358 Da, Ligand)
Electron cryomicroscopy Structure of S. cerevisiae FAS in the KS-stalled state
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 6u5u
Q-score: 0.449
Lou JW, Iyer KR, Hasan SMN, Cowen LE, Mazhab-Jafari MT
Sci Rep (2019) 9 pp. 12987-12987 [ DOI: doi:10.1038/s41598-019-49261-3 Pubmed: 31506493 ]
- Flavin mononucleotide (456 Da, Ligand)
- Fatty acid synthase (2 MDa, Complex from Saccharomyces cerevisiae)
- Fatty acid synthase subunit beta (231 kDa, Protein from Baker's yeast)
- Fatty acid synthase subunit alpha (207 kDa, Protein from Baker's yeast)
- 4'-phosphopantetheine (358 Da, Ligand)
- Nadp nicotinamide-adenine-dinucleotide phosphate (743 Da, Ligand)
Electron cryomicroscopy Structure of C. albicans FAS in the Apo state
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 6u5v
Q-score: 0.453
Lou JW, Iyer KR, Hasan SMN, Cowen LE, Mazhab-Jafari MT
Sci Rep (2019) 9 pp. 12987-12987 [ DOI: doi:10.1038/s41598-019-49261-3 Pubmed: 31506493 ]
- Flavin mononucleotide (456 Da, Ligand)
- Fatty acid synthase (2 MDa, Complex from Candida albicans)
- Fatty acid synthase subunit alpha (207 kDa, Protein from Yeast)
- 4'-phosphopantetheine (358 Da, Ligand)
- Fatty acid synthase subunit beta (228 kDa, Protein from Yeast)
Electron cryomicroscopy structure of C. albicans FAS in the KS-stalled state
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 6u5w
Q-score: 0.428
Lou JW, Iyer KR, Hasan SMN, Cowen LE, Mazhab-Jafari MT
Sci Rep (2019) 9 pp. 12987-12987 [ DOI: doi:10.1038/s41598-019-49261-3 Pubmed: 31506493 ]
- Fatty acid synthase (2 MDa, Complex from Candida albicans)
- Flavin mononucleotide (456 Da, Ligand)
- Nadp nicotinamide-adenine-dinucleotide phosphate (743 Da, Ligand)
- Fatty acid synthase subunit beta (228 kDa, Protein from Candida albicans)
- Fatty acid synthase subunit alpha (190 kDa, Protein from Candida albicans)