Structure of CX3CL1-US28-G11iN18-scFv16 in TL-state
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7rkf
Q-score: 0.44
Tsutsumi N, Maeda S, Qu Q, Voegele M, Jude KM, Suomivuori CM, Panova O, Waghray D, Kato HE, Velasco A, Dror RO, Skiniotis G, Kobilka BK, Garcia KC
Sci Adv (2022) 8 pp. eabl5442- [ DOI: doi:10.1126/sciadv.abl5442 ]
- G11in18 heterotrimer (90 kDa, Complex from Homo sapiens)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Fractalkine (10 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Cx3cl1-us28 (50 kDa, Complex from Human betaherpesvirus 5)
- G-protein coupled receptor homolog us28 (42 kDa, Protein from Human cytomegalovirus)
- Guanine nucleotide-binding protein subunit alpha-11 (41 kDa, Protein from Homo sapiens)
- Cx3cl1-us28-g11in18-scfv16 complex (Complex)
- Scfv16 (30 kDa, Complex from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Antibody fragment scfv16 (27 kDa, Protein from Mus musculus)
Structure of CX3CL1-US28-Gi-scFv16 in C-state
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7rkm
Q-score: 0.477
Tsutsumi N, Maeda S, Qu Q, Voegele M, Jude KM, Suomivuori CM, Panova O, Waghray D, Kato HE, Velasco A, Dror RO, Skiniotis G, Kobilka BK, Garcia KC
Sci Adv (2022) 8 pp. eabl5442- [ DOI: doi:10.1126/sciadv.abl5442 ]
- Fractalkine (10 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Cx3cl1-us28 (50 kDa, Complex from Human betaherpesvirus 5)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Scfv16 (30 kDa, Complex from Mus musculus)
- Antibody fragment scfv16 (27 kDa, Protein from Mus musculus)
- Gi heterotrimer (90 kDa, Complex from Homo sapiens)
- Cx3cl1-us28-gi-scfv16 complex (Complex)
- G-protein coupled receptor homolog us28 (42 kDa, Protein from Human betaherpesvirus 5)
Structure of CX3CL1-US28-Gi-scFv16 in OC-state
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7rkn
Q-score: 0.447
Tsutsumi N, Maeda S, Qu Q, Voegele M, Jude KM, Suomivuori CM, Panova O, Waghray D, Kato HE, Velasco A, Dror RO, Skiniotis G, Kobilka BK, Garcia KC
Sci Adv (2022) 8 pp. eabl5442- [ DOI: doi:10.1126/sciadv.abl5442 ]
- Fractalkine (10 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- G-protein coupled receptor homolog us28 (42 kDa, Protein from Human cytomegalovirus)
- Cx3cl1-us28 (50 kDa, Complex from Human betaherpesvirus 5)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Scfv16 (30 kDa, Complex from Mus musculus)
- Antibody fragment scfv16 (27 kDa, Protein from Mus musculus)
- Gi heterotrimer (90 kDa, Complex from Homo sapiens)
- Cx3cl1-us28-gi-scfv16 complex (Complex)
Cryo-EM structure of the beclomethasone-bound adhesion receptor GPR97-Go complex
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7d76
Q-score: 0.526
Ping YQ, Mao C, Xiao P, Zhao RJ, Jiang Y, Yang Z, An WT, Shen DD, Yang F, Zhang H, Qu C, Shen Q, Tian C, Li ZJ, Li S, Wang GY, Tao X, Wen X, Zhong YN, Yang J, Yi F, Yu X, Xu HE, Zhang Y, Sun JP
Nature (2021) 589 pp. 620-626 [ DOI: doi:10.1038/s41586-020-03083-w Pubmed: 33408414 ]
- (8~{s},9~{r},10~{s},11~{s},13~{s},14~{s},16~{s},17~{r})-9-chloranyl-10,13,16-trimethyl-11,17-bis(oxidanyl)-17-(2-oxidanylethanoyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one (408 Da, Ligand)
- Palmitic acid (256 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Adhesion g protein-coupled receptor g3; gpr97 (Complex from Homo sapiens)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Guanine nucleotide-binding protein g(o) subunit alpha (25 kDa, Protein from Homo sapiens)
- Beclomethasone-bound adhesion receptor gpr97-go complex (Complex)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- Go (Complex from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Adhesion g protein-coupled receptor g3; gpr97 (62 kDa, Protein from Homo sapiens)
Cryo-EM structure of the cortisol-bound adhesion receptor GPR97-Go complex
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7d77
Q-score: 0.56
Ping YQ, Mao C, Xiao P, Zhao RJ, Jiang Y, Yang Z, An WT, Shen DD, Yang F, Zhang H, Qu C, Shen Q, Tian C, Li ZJ, Li S, Wang GY, Tao X, Wen X, Zhong YN, Yang J, Yi F, Yu X, Xu HE, Zhang Y, Sun JP
Nature (2021) 589 pp. 620-626 [ DOI: doi:10.1038/s41586-020-03083-w Pubmed: 33408414 ]
- (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione (362 Da, Ligand)
- Water (18 Da, Ligand)
- Palmitic acid (256 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Adhesion g protein-coupled receptor g3; gpr97 (Complex from Homo sapiens)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Scfv16 (26 kDa, Protein from synthetic construct)
- Guanine nucleotide-binding protein g(o) subunit alpha (25 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- Go (Complex from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Cortisol-bound adhesion receptor gpr97-go complex (Complex)
- Adhesion g protein-coupled receptor g3; gpr97 (62 kDa, Protein from Homo sapiens)
- Scfv16 (Complex from synthetic construct)
Human Teneurin-2 and human Latrophilin-3 binary complex
Resolution: 2.97 Å
EM Method: Single-particle
Fitted PDBs: 6vhh
Q-score: 0.502
Li J, Xie Y, Cornelius S, Jiang X, Sando R, Kordon SP, Pan M, Leon K, Sudhof TC, Zhao M, Arac D
Nat Commun (2020) 11 pp. 2140-2140 [ DOI: doi:10.1038/s41467-020-16029-7 Pubmed: 32358586 ]
- Teneurin-2 (216 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Adhesion g protein-coupled receptor l3 (95 kDa, Protein from Homo sapiens)
- Binary complex of human teneurin-2 with human latrophilin-3 extracellular domain (314 kDa, Complex from Homo sapiens)