Gag CA-SP1 immature lattice bound with Lenacapavir from enveloped virus like particles
Resolution: 2.18 Å
EM Method: Single-particle
Fitted PDBs: 9d6d
Q-score: 0.587
Wu C, Meuser ME, Rey JS, Meshkin H, Yang R, Devarkar SC, Freniere C, Shi J, Aiken C, Perilla JR, Xiong Y
bioRxiv (2024) [ DOI: doi:10.1101/2024.10.09.617473 Pubmed: 39416065 ]
- Water (18 Da, Ligand)
- Lenacapavir (968 Da, Ligand)
- Inositol hexakisphosphate (660 Da, Ligand)
- Gag polyprotein (25 kDa, Protein from Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE))
- Human immunodeficiency virus type 1 (new york-5 isolate) (Virus from Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE))
Gag CA-SP1 immature lattice bound with Bevirimat from enveloped virus like particles
Resolution: 3.09 Å
EM Method: Single-particle
Fitted PDBs: 9d6e
Q-score: 0.467
Wu C, Meuser ME, Rey JS, Meshkin H, Yang R, Devarkar SC, Freniere C, Shi J, Aiken C, Perilla JR, Xiong Y
bioRxiv (2024) [ DOI: doi:10.1101/2024.10.09.617473 Pubmed: 39416065 ]
- Gag polyprotein (25 kDa, Protein from Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE))
- Inositol hexakisphosphate (660 Da, Ligand)
- Human immunodeficiency virus type 1 (new york-5 isolate) (Virus from Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE))
- 3alpha-[(3-carboxy-3-methylbutanoyl)oxy]-8alpha,9beta,10alpha,13alpha,17alpha,19beta-lup-20(29)-en-28-oic acid (584 Da, Ligand)
Gag CA-SP1 immature lattice from enveloped and perforated virus like particles
Resolution: 3.18 Å
EM Method: Single-particle
Fitted PDBs: 9d88
Q-score: 0.474
Wu C, Meuser ME, Rey JS, Meshkin H, Yang R, Devarkar SC, Freniere C, Shi J, Aiken C, Perilla JR, Xiong Y
bioRxiv (2024) [ DOI: doi:10.1101/2024.10.09.617473 Pubmed: 39416065 ]
A 3.7 Angstrom structure of the EIAV CA-SP hexamer (C2) from Gag-deltaMA tubes assembled at pH8
Resolution: 3.7 Å
EM Method: Subtomogram averaging
Fitted PDBs: 6t61
Q-score: 0.419
Dick RA, Xu C, Morado DR, Kravchuk V, Ricana CL, Lyddon TD, Broad AM, Feathers JR, Johnson MC, Vogt VM, Perilla JR, Briggs JAG, Schur FKM
PLoS Pathog (2020) 16 pp. e1008277-e1008277 [ DOI: doi:10.1371/journal.ppat.1008277 Pubmed: 31986188 ]
A structure of the EIAV CA-SP hexamer (C2) from Gag-deltaMA tubes assembled at pH6
Resolution: 3.8 Å
EM Method: Subtomogram averaging
Fitted PDBs: 6t63
Q-score: 0.435
Dick RA, Xu C, Morado DR, Kravchuk V, Ricana CL, Lyddon TD, Broad AM, Feathers JR, Johnson MC, Vogt VM, Perilla JR, Briggs JAG, Schur FKM
PLoS Pathog (2020) 16 pp. e1008277-e1008277 [ DOI: doi:10.1371/journal.ppat.1008277 Pubmed: 31986188 ]
A structure of the EIAV CA-SP hexamer (C6) from Gag-deltaMA spheres assembled at pH6
Resolution: 3.7 Å
EM Method: Subtomogram averaging
Fitted PDBs: 6t64
Q-score: 0.409
Dick RA, Xu C, Morado DR, Kravchuk V, Ricana CL, Lyddon TD, Broad AM, Feathers JR, Johnson MC, Vogt VM, Perilla JR, Briggs JAG, Schur FKM
PLoS Pathog (2020) 16 pp. e1008277-e1008277 [ DOI: doi:10.1371/journal.ppat.1008277 Pubmed: 31986188 ]
CryoEM Structure Refinement by Integrating NMR Chemical Shifts with Molecular Dynamics Simulations
Resolution: 5.0 Å
EM Method: Helical reconstruction
Fitted PDBs: 5upw
Q-score: 0.207
Perilla JR, Zhao G, Lu M, Ning J, Hou G, Byeon IL, Gronenborn AM, Polenova T, Zhang P
J Phys Chem B (2017) 121 pp. 3853-3863 [ DOI: doi:10.1021/acs.jpcb.6b13105 Pubmed: 28181439 ]