Gag CA-SP1 immature lattice bound with Lenacapavir from enveloped virus like particles
Resolution: 2.18 Å
EM Method: Single-particle
Fitted PDBs: 9d6d
Q-score: 0.587
Wu C, Meuser ME, Rey JS, Meshkin H, Yang R, Devarkar SC, Freniere C, Shi J, Aiken C, Perilla JR, Xiong Y
bioRxiv (2024) [ DOI: doi:10.1101/2024.10.09.617473 Pubmed: 39416065 ]
- Water (18 Da, Ligand)
- Lenacapavir (968 Da, Ligand)
- Inositol hexakisphosphate (660 Da, Ligand)
- Gag polyprotein (25 kDa, Protein from Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE))
- Human immunodeficiency virus type 1 (new york-5 isolate) (Virus from Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE))
HIV-1 mature capsid hexamer from CA-IP6 CLPs
Resolution: 2.89 Å
EM Method: Single-particle
Fitted PDBs: 8ckv
Q-score: 0.547
Stacey JCV, Tan A, Lu JM, James LC, Dick RA, Briggs JAG
PNAS (2023) 120 pp. e2220557120-e2220557120 [ DOI: doi:10.1073/pnas.2220557120 Pubmed: 37040417 ]
- Hiv-1 mature capsid (26 kDa, Complex from Human immunodeficiency virus 1)
- Gag polyprotein (25 kDa, Protein from Human immunodeficiency virus 1)
HIV-1 mature capsid hexamer next to pentamer (type I) from CA-IP6 CLPs
Resolution: 2.97 Å
EM Method: Single-particle
Fitted PDBs: 8ckx
Q-score: 0.522
Stacey JCV, Tan A, Lu JM, James LC, Dick RA, Briggs JAG
PNAS (2023) 120 pp. e2220557120-e2220557120 [ DOI: doi:10.1073/pnas.2220557120 Pubmed: 37040417 ]
- Gag polyprotein (25 kDa, Protein from Human immunodeficiency virus 1)
- Hiv-1 mature capsid (26 kDa, Complex from Human immunodeficiency virus 1)
HIV-1 mature capsid hexamer from CA-IP6 CLPs, bound to Nup153 peptide
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8cky
Q-score: 0.597
Stacey JCV, Tan A, Lu JM, James LC, Dick RA, Briggs JAG
PNAS (2023) 120 pp. e2220557120-e2220557120 [ DOI: doi:10.1073/pnas.2220557120 Pubmed: 37040417 ]
- Nuclear pore complex protein nup153 (1 kDa, Protein from Homo sapiens)
- Gag polyprotein (25 kDa, Protein from Human immunodeficiency virus 1)
- Hiv-1 mature capsid (27 kDa, Complex from Human immunodeficiency virus 1)
T=1 particle HIV-1 CA G60A/G61P/M66A
Resolution: 2.39 Å
EM Method: Single-particle
Fitted PDBs: 7urt
Q-score: 0.597
Schirra RT, Dos Santos NFB, Zadrozny KK, Kucharska I, Ganser-Pornillos BK, Pornillos O
Nat Struct Mol Biol (2023) 30 pp. 383-390 [ DOI: doi:10.1038/s41594-022-00913-5 Pubmed: 36759579 ]
T=1 particle HIV-1 CA G60A/G61P
Resolution: 2.2 Å
EM Method: Single-particle
Fitted PDBs: 8eep
Q-score: 0.593
Schirra RT, Dos Santos NFB, Zadrozny KK, Kucharska I, Ganser-Pornillos BK, Pornillos O
Nat Struct Mol Biol (2023) 30 pp. 383-390 [ DOI: doi:10.1038/s41594-022-00913-5 Pubmed: 36759579 ]
Human endogenous retrovirus (HML2) mature capsid assembly, T=1 icosahedron
Resolution: 2.75 Å
EM Method: Single-particle
Fitted PDBs: 6ssj
Q-score: 0.557
Acton O, Grant T, Nicastro G, Ball NJ, Goldstone DC, Robertson LE, Sader K, Nans A, Ramos A, Stoye JP, Taylor IA, Rosenthal PB
Nat Commun (2019) 10 pp. 5822-5822 [ Pubmed: 31862888 DOI: doi:10.1038/s41467-019-13786-y ]