human connexin-36 gap junction channel in complex with mefloquine
Resolution: 2.13 Å
EM Method: Single-particle
Fitted PDBs: 8qoj
Q-score: 0.657
Ding X, Aureli S, Vaithia A, Lavriha P, Schuster D, Khanppnavar B, Li X, Blum TB, Picotti P, Gervasio FL, Korkhov VM
Cell Discov (2024) 10 pp. 68-68 [ DOI: doi:10.1038/s41421-024-00691-y Pubmed: 38890333 ]
- Human connexin-36 gap junction channel in complex with mefloquine (Complex from Homo sapiens)
- Water (18 Da, Ligand)
- Gap junction delta-2 protein (37 kDa, Protein from Homo sapiens)
- (11r,12s)- mefloquine (378 Da, Ligand)
human connexin-36 gap junction channel
Resolution: 2.53 Å
EM Method: Single-particle
Fitted PDBs: 8r7p
Q-score: 0.62
Ding X, Aureli S, Vaithia A, Lavriha P, Schuster D, Khanppnavar B, Li X, Blum TB, Picotti P, Gervasio FL, Korkhov VM
Cell Discov (2024) 10 pp. 68-68 [ DOI: doi:10.1038/s41421-024-00691-y Pubmed: 38890333 ]
- Human connexin-36 gap junction channel (Complex from Homo sapiens)
- Water (18 Da, Ligand)
- Gap junction delta-2 protein (37 kDa, Protein from Homo sapiens)
human connexin-36 gap junction channel in complex with quinine
Resolution: 2.78 Å
EM Method: Single-particle
Fitted PDBs: 8r7q
Q-score: 0.602
Ding X, Aureli S, Vaithia A, Lavriha P, Schuster D, Khanppnavar B, Li X, Blum TB, Picotti P, Gervasio FL, Korkhov VM
Cell Discov (2024) 10 pp. 68-68 [ DOI: doi:10.1038/s41421-024-00691-y Pubmed: 38890333 ]
- Quinine (324 Da, Ligand)
- Human connexin-36 gap junction channel in complex with quinine (Complex from Homo sapiens)
- Gap junction delta-2 protein (37 kDa, Protein from Homo sapiens)
Connexin43 gap junction channel structure in digitonin
Resolution: 2.26 Å
EM Method: Single-particle
Fitted PDBs: 7z1t
Q-score: 0.605
Qi C, Acosta Gutierrez S, Lavriha P, Othman A, Lopez-Pigozzi D, Bayraktar E, Schuster D, Picotti P, Zamboni N, Bortolozzi M, Gervasio FL, Korkhov VM
eLife (2023) 12 [ Pubmed: 37535063 DOI: doi:10.7554/eLife.87616 ]
- Connexin43 gap junction channel (43 MDa, Complex from Homo sapiens)
- Gap junction alpha-1 protein (43 kDa, Protein from Homo sapiens)
Connexin43 gap junction channel structure in nanodisc
Resolution: 2.95 Å
EM Method: Single-particle
Fitted PDBs: 7z22
Q-score: 0.201
Qi C, Acosta Gutierrez S, Lavriha P, Othman A, Lopez-Pigozzi D, Bayraktar E, Schuster D, Picotti P, Zamboni N, Bortolozzi M, Gervasio FL, Korkhov VM
eLife (2023) 12 [ Pubmed: 37535063 DOI: doi:10.7554/eLife.87616 ]
- Connexin43 gap junction channel (43 MDa, Complex from Homo sapiens)
- Gap junction alpha-1 protein (43 kDa, Protein from Homo sapiens)
Connexin43 gap junction channel structure in digitonin
Resolution: 3.98 Å
EM Method: Single-particle
Fitted PDBs: 7z23
Q-score: 0.258
Qi C, Acosta Gutierrez S, Lavriha P, Othman A, Lopez-Pigozzi D, Bayraktar E, Schuster D, Picotti P, Zamboni N, Bortolozzi M, Gervasio FL, Korkhov VM
eLife (2023) 12 [ Pubmed: 37535063 DOI: doi:10.7554/eLife.87616 ]
- Connexin43 gap junction channel (43 MDa, Complex from Homo sapiens)
- Gap junction alpha-1 protein (43 kDa, Protein from Homo sapiens)