Human Cx36/GJD2 (BRIL-fused mutant) gap junction channel in detergents at 2.2 Angstroms resolution
Resolution: 2.2 Å
EM Method: Single-particle
Fitted PDBs: 7xkt
Q-score: 0.649
Lee SN, Cho HJ, Jeong H, Ryu B, Lee HJ, Kim M, Yoo J, Woo JS, Lee HH
Nat Commun (2023) 14 pp. 1347-1347 [ Pubmed: 36906653 DOI: doi:10.1038/s41467-023-37040-8 ]
- Gap junction delta-2 protein,soluble cytochrome b562 (40 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Cx36-bril (Complex from Homo sapiens)
- 1,2-dimyristoyl-rac-glycero-3-phosphocholine (677 Da, Ligand)
- 1,2-dipalmitoyl-phosphatidyl-glycerole (722 Da, Ligand)
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 7xqd
Q-score: 0.558
Lee HJ, Cha HJ, Jeong H, Lee SN, Lee CW, Kim M, Yoo J, Woo JS
Nat Commun (2023) 14 pp. 931-931 [ DOI: doi:10.1038/s41467-023-36593-y Pubmed: 36805660 ]
- Water (18 Da, Ligand)
- Tetradecane (198 Da, Ligand)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Dodecameric complex of c-terminal deletion mutant of human cx43/gja1 (cx43-m257) in lipid nanodiscs (pope/chs) (Complex from Homo sapiens)
- Phosphatidylethanolamine (734 Da, Ligand)
- Gap junction alpha-1 protein (29 kDa, Protein from Homo sapiens)
Resolution: 2.3 Å
EM Method: Single-particle
Fitted PDBs: 7xqf
Q-score: 0.622
Lee HJ, Cha HJ, Jeong H, Lee SN, Lee CW, Kim M, Yoo J, Woo JS
Nat Commun (2023) 14 pp. 931-931 [ DOI: doi:10.1038/s41467-023-36593-y Pubmed: 36805660 ]
- Water (18 Da, Ligand)
- Tetradecane (198 Da, Ligand)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Dodecameric complex of c-terminal deletion mutant of human cx43/gja1 (cx43-m257) in lipid nanodiscs (pope/chs) (Complex from Homo sapiens)
- Phosphatidylethanolamine (734 Da, Ligand)
- Gap junction alpha-1 protein (29 kDa, Protein from Homo sapiens)
Human Cx31.3/GJC3 connexin hemichannel in the absence of calcium
Resolution: 2.34 Å
EM Method: Single-particle
Fitted PDBs: 6l3t
Q-score: 0.679
Lee HJ, Jeong H, Hyun J, Ryu B, Park K, Lim HH, Yoo J, Woo JS
Sci Adv (2020) 6 pp. eaba4996-eaba4996 [ DOI: doi:10.1126/sciadv.aba4996 Pubmed: 32923625 ]
- Lauryl maltose neopentyl glycol (1 kDa, Ligand)
- Human cx31.3/gjc3 connexin hemichannel in the absence of calcium (Complex from Homo sapiens)
- Water (18 Da, Ligand)
- Gap junction gamma-3 protein (31 kDa, Protein from Homo sapiens)
Human Cx31.3/GJC3 connexin hemichannel in the presence of calcium
Resolution: 2.53 Å
EM Method: Single-particle
Fitted PDBs: 6l3u
Q-score: 0.637
Lee HJ, Jeong H, Hyun J, Ryu B, Park K, Lim HH, Yoo J, Woo JS
Sci Adv (2020) 6 pp. eaba4996-eaba4996 [ DOI: doi:10.1126/sciadv.aba4996 Pubmed: 32923625 ]
- Lauryl maltose neopentyl glycol (1 kDa, Ligand)
- Human cx31.3/gjc3 connexin hemichannel in the presence of calcium (Complex from Homo sapiens)
- Water (18 Da, Ligand)
- Gap junction gamma-3 protein (31 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
