Cryo-EM structure of non gastric H,K-ATPase alpha2 K794A in (K+)E2-AlF state
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7x21
Q-score: 0.566
Young VC, Nakanishi H, Meyer DJ, Nishizawa T, Oshima A, Artigas P, Abe K
Nat Commun (2022) 13 pp. 5270-5270 [ Pubmed: 36085139 DOI: doi:10.1038/s41467-022-32793-0 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 1,2-dioleoyl-sn-glycero-3-phosphocholine (787 Da, Ligand)
- Tetrafluoroaluminate ion (102 Da, Ligand)
- Potassium ion (39 Da, Ligand)
- Non gastric h,k-atpase (150 MDa, Complex from Rattus norvegicus)
- Magnesium ion (24 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Sodium/potassium-transporting atpase subunit beta-1 (37 kDa, Protein from Rattus norvegicus)
- Water (18 Da, Ligand)
- Potassium-transporting atpase alpha chain 2 (109 kDa, Protein from Rattus norvegicus)
Cryo-EM structure of non gastric H,K-ATPase alpha2 K794S in (2K+)E2-AlF state
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7x22
Q-score: 0.508
Young VC, Nakanishi H, Meyer DJ, Nishizawa T, Oshima A, Artigas P, Abe K
Nat Commun (2022) 13 pp. 5270-5270 [ Pubmed: 36085139 DOI: doi:10.1038/s41467-022-32793-0 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 1,2-dioleoyl-sn-glycero-3-phosphocholine (787 Da, Ligand)
- Non gastric h,k-atpase (150 MDa, Complex from Rattus norvegicus)
- Potassium ion (39 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Potassium-transporting atpase alpha chain 2 (109 kDa, Protein from Rattus norvegicus)
- Cholesterol (386 Da, Ligand)
- Sodium/potassium-transporting atpase subunit beta-1 (37 kDa, Protein from Rattus norvegicus)
- Water (18 Da, Ligand)
- Tetrafluoroaluminate ion (102 Da, Ligand)
Cryo-EM structure of non gastric H,K-ATPase alpha2 SPWC mutant in 3Na+E1-AMPPCPF state
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7x23
Q-score: 0.35
Young VC, Nakanishi H, Meyer DJ, Nishizawa T, Oshima A, Artigas P, Abe K
Nat Commun (2022) 13 pp. 5270-5270 [ Pubmed: 36085139 DOI: doi:10.1038/s41467-022-32793-0 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Potassium-transporting atpase alpha chain 2 (109 kDa, Protein from Rattus norvegicus)
- Non gastric h,k-atpase (150 MDa, Complex from Rattus norvegicus)
- Sodium ion (22 Da, Ligand)
- Phosphomethylphosphonic acid adenylate ester (505 Da, Ligand)
- Sodium/potassium-transporting atpase subunit beta-1 (37 kDa, Protein from Rattus norvegicus)
- Water (18 Da, Ligand)
Cryo-EM structure of non gastric H,K-ATPase alpha2 SPWC mutant in (2K+)E2-AlF state
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7x24
Q-score: 0.515
Young VC, Nakanishi H, Meyer DJ, Nishizawa T, Oshima A, Artigas P, Abe K
Nat Commun (2022) 13 pp. 5270-5270 [ Pubmed: 36085139 DOI: doi:10.1038/s41467-022-32793-0 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Potassium-transporting atpase alpha chain 2 (109 kDa, Protein from Rattus norvegicus)
- 1,2-dioleoyl-sn-glycero-3-phosphocholine (787 Da, Ligand)
- Potassium ion (39 Da, Ligand)
- Tetrafluoroaluminate ion (102 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Sodium/potassium-transporting atpase subunit beta-1 (37 kDa, Protein from Rattus norvegicus)
- Non gastric h,k-atpase (150 MDa, Complex from Rattus norvegicus)
PIG GASTRIC H+/K+ - ATPASE IN COMPLEX WITH BYK99
Resolution: 6.5 Å
EM Method: Electron Crystallography
Fitted PDBs: 5y0b
Q-score: 0.115
Abe K, Shimokawa J, Naito M, Munson K, Vagin O, Sachs G, Suzuki H, Tani K, Fujiyoshi Y
Sci Rep (2017) 7 pp. 6632-6632 [ DOI: doi:10.1038/s41598-017-06698-8 Pubmed: 28747707 ]
Pig Gastric H,K-ATPase with bound BeF and SCH28080
Resolution: 7.0 Å
EM Method: Electron Crystallography
Fitted PDBs: 2xzb
Q-score: 0.108
Nat Commun (2011) 2 pp. 155-155 [ Pubmed: 21224846 DOI: doi:10.1038/ncomms1154 ]
- Potassium-transporting atpase subunit beta (150 kDa, Protein from Sus scrofa)
- Potassium-transporting atpase alpha chain 1 (150 kDa, Protein from Sus scrofa)
- Pig gastric h,k-atpase (150 kDa, Sample)