Human GluN1-2B with Fab 007-168
Resolution: 4.05 Å
EM Method: Single-particle
Fitted PDBs: 8vuu
Q-score: 0.316
Michalski K, Abdulla T, Kleeman S, Schmidl L, Gomez R, Simorowski N, Vallese F, Pruss H, Heckmann M, Geis C, Furukawa H
Nat Struct Mol Biol (2024) 31 pp. 1975-1986 [ Pubmed: 39227719 DOI: doi:10.1038/s41594-024-01386-4 ]
- Human glun1-2b with fab 007-168 (Complex from Homo sapiens)
- 007-168 light (23 kDa, Protein from Homo sapiens)
- Glutamate receptor ionotropic, nmda 2b (91 kDa, Protein from Homo sapiens)
- 007-168 heavy (22 kDa, Protein from Homo sapiens)
- Glutamate receptor ionotropic, nmda 1 (92 kDa, Protein from Homo sapiens)
Human GluN1-2B with Fab 007-168 Local refinement of ATD
Resolution: 3.69 Å
EM Method: Single-particle
Fitted PDBs: 8vuv
Q-score: 0.394
Michalski K, Abdulla T, Kleeman S, Schmidl L, Gomez R, Simorowski N, Vallese F, Pruss H, Heckmann M, Geis C, Furukawa H
Nat Struct Mol Biol (2024) 31 pp. 1975-1986 [ Pubmed: 39227719 DOI: doi:10.1038/s41594-024-01386-4 ]
- Glutamate receptor ionotropic, nmda 2b (40 kDa, Protein from Homo sapiens)
- Human glun1-2b with fab 007-168 local refinement of atd (Complex from Homo sapiens)
- Glutamate receptor ionotropic, nmda 1 (41 kDa, Protein from Homo sapiens)
- 007-168 light (23 kDa, Protein from Homo sapiens)
- 007-168 heavy (22 kDa, Protein from Homo sapiens)
Resolution: 3.81 Å
EM Method: Single-particle
Fitted PDBs: 8vuy
Q-score: 0.394
Michalski K, Abdulla T, Kleeman S, Schmidl L, Gomez R, Simorowski N, Vallese F, Pruss H, Heckmann M, Geis C, Furukawa H
Nat Struct Mol Biol (2024) 31 pp. 1975-1986 [ Pubmed: 39227719 DOI: doi:10.1038/s41594-024-01386-4 ]
- Rat glun1-2b with fab 003-102 (Complex from Homo sapiens)
- Glutamate receptor ionotropic, nmda 2b (91 kDa, Protein from Rattus norvegicus)
- 003-102 heavy (12 kDa, Protein from Homo sapiens)
- Glutamate receptor ionotropic, nmda 1 (91 kDa, Protein from Rattus norvegicus)
- 003-102 light (11 kDa, Protein from Homo sapiens)
rat GluN1a-2B Fab 003-102 local refinement
Resolution: 3.95 Å
EM Method: Single-particle
Fitted PDBs: 8vvh
Q-score: 0.442
Michalski K, Abdulla T, Kleeman S, Schmidl L, Gomez R, Simorowski N, Vallese F, Pruss H, Heckmann M, Geis C, Furukawa H
Nat Struct Mol Biol (2024) 31 pp. 1975-1986 [ Pubmed: 39227719 DOI: doi:10.1038/s41594-024-01386-4 ]
- Rat glun1a-2b fab 003-102 local refinement (Complex from Homo sapiens)
- 003-102 heavy (12 kDa, Protein from Homo sapiens)
- Glutamate receptor ionotropic, nmda 2b (40 kDa, Protein from Rattus norvegicus)
- Glutamate receptor ionotropic, nmda 1 (41 kDa, Protein from Rattus norvegicus)
- 003-102 light (11 kDa, Protein from Homo sapiens)
Cryo-EM structure of GluN1b-2B NMDAR complexed to Fab2 class1
Resolution: 3.92 Å
EM Method: Single-particle
Fitted PDBs: 7te9
Q-score: 0.301
Tajima N, Simorowski N, Yovanno RA, Regan MC, Michalski K, Gomez R, Lau AY, Furukawa H
Nat Commun (2022) 13 pp. 923-923 [ Pubmed: 35177668 DOI: doi:10.1038/s41467-022-28559-3 ]
- Fab2 heavy chain (23 kDa, Protein from Mus musculus)
- Glutamate receptor ionotropic, nmda 1 (96 kDa, Protein from Rattus norvegicus)
- Glutamate receptor ionotropic, nmda 2b (92 kDa, Protein from Rattus norvegicus)
- Fab2 light chain (23 kDa, Protein from Mus musculus)
- Glun1b-2b nmdar - fab2 (Complex from Rattus norvegicus)
Cryo-EM structure of GluN1b-2B NMDAR complexed to Fab2 non-active1-like
Resolution: 4.23 Å
EM Method: Single-particle
Fitted PDBs: 7teb
Q-score: 0.233
Tajima N, Simorowski N, Yovanno RA, Regan MC, Michalski K, Gomez R, Lau AY, Furukawa H
Nat Commun (2022) 13 pp. 923-923 [ Pubmed: 35177668 DOI: doi:10.1038/s41467-022-28559-3 ]
- Fab2 heavy chain (23 kDa, Protein from Mus musculus)
- Glutamate receptor ionotropic, nmda 1 (96 kDa, Protein from Rattus norvegicus)
- Glutamate receptor ionotropic, nmda 2b (98 kDa, Protein from Rattus norvegicus)
- Fab2 light chain (23 kDa, Protein from Mus musculus)
- Glun1b-2b nmdar - fab2 (Complex from Rattus norvegicus)
Cryo-EM structure of GluN1b-2B NMDAR complexed to Fab2 Non-active2-like
Resolution: 6.59 Å
EM Method: Single-particle
Fitted PDBs: 7tee
Q-score: 0.157
Tajima N, Simorowski N, Yovanno RA, Regan MC, Michalski K, Gomez R, Lau AY, Furukawa H
Nat Commun (2022) 13 pp. 923-923 [ Pubmed: 35177668 DOI: doi:10.1038/s41467-022-28559-3 ]
- Fab2 heavy chain (23 kDa, Protein from Mus musculus)
- Glutamate receptor ionotropic, nmda 1 (96 kDa, Protein from Rattus norvegicus)
- Glutamate receptor ionotropic, nmda 2b (98 kDa, Protein from Rattus norvegicus)
- Fab2 light chain (23 kDa, Protein from Mus musculus)
- Glun1b-2b nmdar - fab2 (Complex from Rattus norvegicus)
Cryo-EM structure of GluN1b-2B NMDAR in complex with Fab5 active conformation
Resolution: 7.51 Å
EM Method: Single-particle
Fitted PDBs: 7teq
Q-score: 0.169
Tajima N, Simorowski N, Yovanno RA, Regan MC, Michalski K, Gomez R, Lau AY, Furukawa H
Nat Commun (2022) 13 pp. 923-923 [ Pubmed: 35177668 DOI: doi:10.1038/s41467-022-28559-3 ]
- Glun1b-2b nmdar complexed to fab5 (Complex from Rattus norvegicus)
- Fab5 heavy chain (23 kDa, Protein from Mus musculus)
- Glutamate receptor ionotropic, nmda 1 (96 kDa, Protein from Rattus norvegicus)
- Fab5 light chain (23 kDa, Protein from Mus musculus)
- Glutamate receptor ionotropic, nmda 2b (98 kDa, Protein from Rattus norvegicus)
Cryo-EM structure of GluN1b-2B NMDAR in complex with Fab5 non-active2 conformation
Resolution: 5.23 Å
EM Method: Single-particle
Fitted PDBs: 7ter
Q-score: 0.188
Tajima N, Simorowski N, Yovanno RA, Regan MC, Michalski K, Gomez R, Lau AY, Furukawa H
Nat Commun (2022) 13 pp. 923-923 [ Pubmed: 35177668 DOI: doi:10.1038/s41467-022-28559-3 ]
- Glun1b-2b nmdar complexed to fab5 (Complex from Rattus norvegicus)
- Fab5 heavy chain (23 kDa, Protein from Mus musculus)
- Glutamate receptor ionotropic, nmda 1 (96 kDa, Protein from Rattus norvegicus)
- Glutamate receptor ionotropic, nmda 2b (98 kDa, Protein from Rattus norvegicus)
- Fab5 light chain (23 kDa, Protein from Mus musculus)
Cryo-EM structure of GluN1b-2B NMDAR in complex with Fab5 in Non-active1 conformation
Resolution: 4.7 Å
EM Method: Single-particle
Fitted PDBs: 7tes
Q-score: 0.197
Tajima N, Simorowski N, Yovanno RA, Regan MC, Michalski K, Gomez R, Lau AY, Furukawa H
Nat Commun (2022) 13 pp. 923-923 [ Pubmed: 35177668 DOI: doi:10.1038/s41467-022-28559-3 ]
- Glun1b-2b nmdar complexed to fab5 (Complex from Rattus norvegicus)
- Fab5 heavy chain (23 kDa, Protein from Mus musculus)
- Glutamate receptor ionotropic, nmda 1 (96 kDa, Protein from Rattus norvegicus)
- Glutamate receptor ionotropic, nmda 2b (98 kDa, Protein from Rattus norvegicus)
- Fab5 light chain (23 kDa, Protein from Mus musculus)