Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 8dn2
Q-score: 0.417
Nat Commun (2023) 14 pp. 6377-6377 [ Pubmed: 37821459 DOI: doi:10.1038/s41467-023-42051-6 ]
- Hexane (86 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Undecane (156 Da, Ligand)
- Glycine receptor subunit alpha-1 (42 kDa, Protein from Homo sapiens)
- N-butane (58 Da, Ligand)
- Decane (142 Da, Ligand)
- Glycine receptor subunit beta,green fluorescent protein,glycine receptor beta (76 kDa, Protein from Homo sapiens)
- Nonane (128 Da, Ligand)
- N-octane (114 Da, Ligand)
- Heptane (100 Da, Ligand)
- Heteromeric glycine receptor subunit alpha-1 and beta, glycine-bound state 2(expanded-open state) (240 kDa, Complex from Homo sapiens)
- Glycine (75 Da, Ligand)
Cryo-EM structure of human Glycine Receptor alpha1-beta heteromer, apo state
Resolution: 3.55 Å
EM Method: Single-particle
Fitted PDBs: 8dn3
Q-score: 0.482
Nat Commun (2023) 14 pp. 6377-6377 [ Pubmed: 37821459 DOI: doi:10.1038/s41467-023-42051-6 ]
- Hexane (86 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Undecane (156 Da, Ligand)
- Heteromeric glycine receptor alpha-1 and beta, apo state (240 kDa, Complex from Homo sapiens)
- Glycine receptor subunit alpha-1 (42 kDa, Protein from Homo sapiens)
- N-butane (58 Da, Ligand)
- Decane (142 Da, Ligand)
- Glycine receptor subunit beta,green fluorescent protein,glycine receptor beta (76 kDa, Protein from Homo sapiens)
- Nonane (128 Da, Ligand)
- Heptane (100 Da, Ligand)
- Chloride ion (35 Da, Ligand)
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 8dn4
Q-score: 0.373
Nat Commun (2023) 14 pp. 6377-6377 [ Pubmed: 37821459 DOI: doi:10.1038/s41467-023-42051-6 ]
- Pentane (72 Da, Ligand)
- Hexane (86 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Glycine receptor subunit alpha-1 (42 kDa, Protein from Homo sapiens)
- N-butane (58 Da, Ligand)
- Nonane (128 Da, Ligand)
- N-octane (114 Da, Ligand)
- Heteromeric glycine receptor subunit alpha-1 and beta, glycine-bound state3(desensitized state) (240 kDa, Complex from Homo sapiens)
- Glycine receptor subunit beta,green fluorescent protein,glycine receptor beta (76 kDa, Protein from Homo sapiens)
Cryo-EM structure of human Glycine Receptor alpha1-beta heteromer, glycine-bound state1(open state)
Resolution: 3.63 Å
EM Method: Single-particle
Fitted PDBs: 8dn5
Q-score: 0.462
Nat Commun (2023) 14 pp. 6377-6377 [ Pubmed: 37821459 DOI: doi:10.1038/s41467-023-42051-6 ]
- Hexane (86 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Heteromeric glycine receptor subunit alpha-1 and beta, glycine-bound state1 (open state) (240 kDa, Complex from Homo sapiens)
- Undecane (156 Da, Ligand)
- Glycine receptor subunit alpha-1 (42 kDa, Protein from Homo sapiens)
- N-butane (58 Da, Ligand)
- Decane (142 Da, Ligand)
- Glycine receptor subunit beta,green fluorescent protein,glycine receptor beta (76 kDa, Protein from Homo sapiens)
- Nonane (128 Da, Ligand)
- N-octane (114 Da, Ligand)
- Heptane (100 Da, Ligand)
- Glycine (75 Da, Ligand)