Cryo-EM structure of Semliki Forest virus in complex with its receptor VLDLR(2-fold)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8x0k
Q-score: 0.436
To Be Published
- Spike glycoprotein e2 (46 kDa, Protein from Semliki Forest virus)
- Very low-density lipoprotein receptor (4 kDa, Protein from Homo sapiens)
- Spike glycoprotein e1 (47 kDa, Protein from Semliki Forest virus)
- Cryo-em structure of semliki forest virus in complex with its receptor vldlr(2-fold) (Complex from Semliki Forest virus)
- Calcium ion (40 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Capsid protein (17 kDa, Protein from Semliki Forest virus)
Cryo-EM structure of Semliki Forest virus in complex with its receptor VLDLR(3-fold)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8x0l
Q-score: 0.455
To Be Published
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Very low-density lipoprotein receptor (4 kDa, Protein from Homo sapiens)
- Pike glycoprotein e2 (46 kDa, Protein from Semliki Forest virus)
- Cryo-em structure of semliki forest virus in complex with its receptor vldlr(3-fold) (Complex from Semliki Forest virus)
- Calcium ion (40 Da, Ligand)
- Pike glycoprotein e1 (47 kDa, Protein from Semliki Forest virus)
- Capsid protein (17 kDa, Protein from Semliki Forest virus)
Cryo-EM structure of Semliki Forest virus in complex with its receptor VLDLR(5-fold)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8x0m
Q-score: 0.405
To Be Published
- Cryo-em structure of semliki forest virus in complex with its receptor vldlr(5-fold) (Complex from Semliki Forest virus)
- Spike glycoprotein e2 (46 kDa, Protein from Semliki Forest virus)
- Spike glycoprotein e1 (47 kDa, Protein from Semliki Forest virus)
- Very low-density lipoprotein receptor (4 kDa, Protein from Semliki Forest virus)
- Calcium ion (40 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Capsid protein (17 kDa, Protein from Semliki Forest virus)
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8u9y
Q-score: 0.437
Shahid S, Liqun J, Liu Y, Hasan SS, Mariuzza RA
To Be Published
- Hc84.26 light chain (25 kDa, Protein from Homo sapiens)
- Envelope glycoprotein e2 (32 kDa, Protein from Hepacivirus)
- Hcv e2-hc84.26 complex (340 kDa, Complex from Homo sapiens)
- Hc84.26 heavy chain (27 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
CryoEM structure of Fab HC84.26-HCV E2 complex
Resolution: 3.75 Å
EM Method: Single-particle
Fitted PDBs: 8tgv
Q-score: 0.425
Shahid S, Liqun J, LIu Y, Hasan SS, Mariuzza RA
To Be Published
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Hcv e2-hc84.26 complex (340 kDa, Complex from Homo sapiens)
- Envelope glycoprotein e2 (32 kDa, Protein from Hepacivirus C)
- Hc84.26 heavy chain (27 kDa, Protein from Homo sapiens)
- Hc84.26 light chain (25 kDa, Protein from Homo sapiens)
Resolution: 3.78 Å
EM Method: Single-particle
Fitted PDBs: 8tgz
Q-score: 0.455
Shahid S, Liqun J, LIu Y, Hasan SS, Mariuzza RA
To Be Published
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Hcv e2-hc84.26 complex (340 kDa, Complex from Homo sapiens)
- Envelope glycoprotein e2 (32 kDa, Protein from Hepacivirus C)
- Hc84.26 heavy chain (27 kDa, Protein from Homo sapiens)
- Hc84.26 light chain (25 kDa, Protein from Homo sapiens)
CryoEM structure of Western equine encephalitis virus VLP in complex with the avian MXRA8 receptor
Resolution: 3.92 Å
EM Method: Single-particle
Fitted PDBs: 8ewf
Q-score: 0.321
Zimmerman O, Zimmerman MI, Nelson CA, Raju S, Errico JM, Madden EA, Hassan AO, VanBlargan LA, Kim AS, Adams LJ, Basore K, Whitener BM, Earnest JT, Holmes AC, Ebel GD, Zmasek C, Scheuermann RH, Fremont DH, Diamond MS
To Be Published
- Chimeric mxra8 receptor: d1 from duck mxra8 and d2 from mouse mxra8 (30 kDa, Protein from Anas platyrhynchos)
- E1 envelope protein (47 kDa, Protein from Chikungunya virus)
- Spike glycoprotein e2 (46 kDa, Protein from Chikungunya virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Chikungunya virus vlp in complex with a chimeric mxra8 receptor (avian d1 with mammalian d2) (495 MDa, Complex from Chikungunya virus)
Resolution: 4.17 Å
EM Method: Single-particle
Fitted PDBs: 8dul
Q-score: 0.241
Sutton MS, Pletnev S, Callahan V, Ko S, Tsybovsky Y, Bylund T, Casner RG, Cerutti G, Gardner CL, Guirguis V, Verardi R, Zhang B, Ambrozak D, Beddall M, Lei H, Yang ES, Liu T, Henry AR, Rawi R, Schon A, Schramm CA, Shen CH, Shi W, Stephens T, Yang Y, Florez MB, Ledgerwood JE, Burke CW, Shapiro L, Fox JM, Kwong PD, Roederer M
Cell (2023) 186 pp. 2672-2689.e25 [ Pubmed: 37295404 DOI: doi:10.1016/j.cell.2023.05.019 ]
- Spike glycoprotein e1 (52 kDa, Protein from Western equine encephalitis virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein e2 (45 kDa, Protein from Western equine encephalitis virus)
- Antibody fab skt05 heavy chain (25 kDa, Protein from Macaca fascicularis)
- Western equine encephalitis virus trimer in complex with antibody fab skt05 (Complex from Western equine encephalitis virus)
- Antibody fab skt05 light chain (23 kDa, Protein from Macaca fascicularis)
Resolution: 5.84 Å
EM Method: Single-particle
Fitted PDBs: 8dun
Q-score: 0.214
Sutton MS, Pletnev S, Callahan V, Ko S, Tsybovsky Y, Bylund T, Casner RG, Cerutti G, Gardner CL, Guirguis V, Verardi R, Zhang B, Ambrozak D, Beddall M, Lei H, Yang ES, Liu T, Henry AR, Rawi R, Schon A, Schramm CA, Shen CH, Shi W, Stephens T, Yang Y, Florez MB, Ledgerwood JE, Burke CW, Shapiro L, Fox JM, Kwong PD, Roederer M
Cell (2023) 186 pp. 2672-2689.e25 [ Pubmed: 37295404 DOI: doi:10.1016/j.cell.2023.05.019 ]
- Spike glycoprotein e1 (52 kDa, Protein from Western equine encephalitis virus)
- Spike glycoprotein e2 (45 kDa, Protein from Western equine encephalitis virus)
- Antibody skw11 heavy chain (24 kDa, Protein from Macaca fascicularis)
- Western equine encephalitis virus trimer in complex with antibody fab skw11 (Complex from Western equine encephalitis virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Antibody skw11 light chain (23 kDa, Protein from Macaca fascicularis)
Cryo-EM local refinement of antibody SKV16 in complex with VEEV alphavirus spike glycoprotein
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8der
Q-score: 0.443
Sutton MS, Pletnev S, Callahan V, Ko S, Tsybovsky Y, Bylund T, Casner RG, Cerutti G, Gardner CL, Guirguis V, Verardi R, Zhang B, Ambrozak D, Beddall M, Lei H, Yang ES, Liu T, Henry AR, Rawi R, Schon A, Schramm CA, Shen CH, Shi W, Stephens T, Yang Y, Florez MB, Ledgerwood JE, Burke CW, Shapiro L, Fox JM, Kwong PD, Roederer M
Cell (2023) 186 pp. 2672-2689.e25 [ Pubmed: 37295404 DOI: doi:10.1016/j.cell.2023.05.019 ]
- Skv16 fab heavy chain (13 kDa, Protein from Macaca)
- Spike glycoprotein e2 (38 kDa, Protein from Venezuelan equine encephalitis virus)
- Cryo-em local refinement of antibody skv16 in complex with veev alphavirus spike glycoprotein (Complex from Venezuelan equine encephalitis virus)
- Spike glycoprotein e1 (43 kDa, Protein from Venezuelan equine encephalitis virus)
- Skv16 fab light chain (11 kDa, Protein from Macaca)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)