Structure of Eastern Equine Encephalitis VLP in complex with the receptor VLDLR LA1-2
Cao D, Ma B, Cao Z, Xu X, Zhang X, Xiang Y
Nat Commun (2024) 15 pp. 6866-6866 [ Pubmed: 39127734 DOI: doi:10.1038/s41467-024-51293-x ]
- Very low-density lipoprotein receptor (9 kDa, Protein from Homo sapiens)
- Spike glycoprotein e1 (47 kDa, Protein from Eastern equine encephalitis virus)
- Spike glycoprotein e2 (47 kDa, Protein from Eastern equine encephalitis virus)
- East equine encephalitis virus vlp in complex with its receptor vldlr la1-2 at the asymmetric unit (Complex from Eastern equine encephalitis virus)
- Calcium ion (40 Da, Ligand)
- Capsid protein (29 kDa, Protein from Eastern equine encephalitis virus)
Structure of Eastern Equine Encephalitis VLP in complex with the receptor VLDLR LA3-5
Cao D, Ma B, Cao Z, Xu X, Zhang X, Xiang Y
Nat Commun (2024) 15 pp. 6866-6866 [ Pubmed: 39127734 DOI: doi:10.1038/s41467-024-51293-x ]
- Very low-density lipoprotein receptor (4 kDa, Protein from Homo sapiens)
- Spike glycoprotein e1 (47 kDa, Protein from Eastern equine encephalitis virus)
- East equine encephalitis virus vlp in complex with its receptor vldlr la3-5 at the asymmetric unit (Complex from Eastern equine encephalitis virus)
- Spike glycoprotein e2 (47 kDa, Protein from Eastern equine encephalitis virus)
- Calcium ion (40 Da, Ligand)
- Capsid protein (29 kDa, Protein from Eastern equine encephalitis virus)
- Very low-density lipoprotein receptor (4 kDa, Protein from Homo sapiens)
Structure of Semliki Forest virus VLP in complex with the receptor VLDLR-LA3
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8ihp
Q-score: 0.556
Cao D, Ma B, Cao Z, Zhang X, Xiang Y
Cell (2023) 186 pp. 2208-2218.e15 [ Pubmed: 37098345 DOI: doi:10.1016/j.cell.2023.03.032 ]
- Spike glycoprotein e2 (46 kDa, Protein from Semliki Forest virus)
- Very low-density lipoprotein receptor (4 kDa, Protein from Homo sapiens)
- Spike glycoprotein e1 (47 kDa, Protein from Semliki Forest virus)
- Semliki forest virus vlp in complex with its receptor vldlr at the asymmetric unit (Complex from Semliki Forest virus)
- Calcium ion (40 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Capsid protein (17 kDa, Protein from Semliki Forest virus)
Eilat virus/Eastern equine encephalitis virus chimeric vaccine candidate
Kaelber JT, Chmielewski D, Chiu W, Auguste AJ
Viruses (2022) 14 [ DOI: doi:10.3390/v14122650 Pubmed: 36560655 ]
- Synthetic viruses (Virus from synthetic viruses)
- Eeev nucleocapsid protein (Protein from Eastern equine encephalitis virus)
- Eeev glycoprotein e1 (Protein from Eastern equine encephalitis virus)
- Eeev glycoprotein e3 (Protein from Eastern equine encephalitis virus)
- Eeev glycoprotein e2 (Protein from Eastern equine encephalitis virus)
Resolution: 3.83 Å
EM Method: Single-particle
Fitted PDBs: 7t6x
Q-score: 0.381
Torrents de la Pena A, Sliepen K, Eshun-Wilson L, Newby ML, Allen JD, Zon I, Koekkoek S, Chumbe A, Crispin M, Schinkel J, Lander GC, Sanders RW, Ward AB
Science (2022) 378 pp. 263-269 [ DOI: doi:10.1126/science.abn9884 Pubmed: 36264808 ]
- Igh505, lambda light chain (24 kDa, Protein from Homo sapiens)
- At12009 crossmab, light kappa chain (24 kDa, Protein from Homo sapiens)
- Ar4a fab, heavy chain (29 kDa, Protein from Homo sapiens)
- Ar4a, kappa light chain (25 kDa, Protein from Homo sapiens)
- Envelope glycoprotein e2 (40 kDa, Protein from Hepacivirus C)
- Igh505, heavy chain (52 kDa, Protein from Homo sapiens)
- Envelope glycoprotein e1 (20 kDa, Protein from Hepacivirus C)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- At12009 crossmab, heavy chain (29 kDa, Protein from Homo sapiens)
- Cryoem structure of full-length hepatitis c virus e1e2 glycoprotein in complex with ar4a, at12009 and igh505 fabs (Complex from Hepacivirus C)
Cryo-EM structure of alphavirus, Getah virus
Resolution: 6.0 Å
EM Method: Single-particle
Fitted PDBs: 7vga
Q-score: 0.246
To Be Published
- Spike glycoprotein e1 (47 kDa, Protein from Getah virus)
- Spike glycoprotein e2 (46 kDa, Protein from Getah virus)
- Capsid protein (30 kDa, Protein from Getah virus)
- Getah virus (Virus from Getah virus)
Cryo-EM structure of alphavirus, Getah virus
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7wc2
Q-score: 0.301
To Be Published
- Spike glycoprotein e1 (47 kDa, Protein from Getah virus)
- Spike glycoprotein e2 (46 kDa, Protein from Getah virus)
- Getah virus (Virus from Getah virus)
Cryo-EM structure of alphavirus, Getah virus
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7wco
Q-score: 0.493
To Be Published
- Spike glycoprotein e1 (47 kDa, Protein from Getah virus)
- Spike glycoprotein e2 (46 kDa, Protein from Getah virus)
- Capsid protein (30 kDa, Protein from Getah virus)
- Getah virus (Virus from Getah virus)
Late pre-fusion state of EEEV (pH 5.5) with localized reconstruction
Resolution: 14.1 Å
EM Method: Single-particle
Fitted PDBs: 7n69
Q-score: 0.081
Chen CL, Klose T, Sun C, Kim AS, Buda G, Rossmann MG, Diamond MS, Klimstra WB, Kuhn RJ
PNAS (2022) 119 pp. e2114119119-e2114119119 [ DOI: doi:10.1073/pnas.2114119119 Pubmed: 35867819 ]
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7ffe
Q-score: 0.425
Ma B, Huang C, Ma J, Xiang Y, Zhang X
Nature (2021) 598 pp. 677-681 [ DOI: doi:10.1038/s41586-021-03909-1 Pubmed: 34646021 ]
- Spike glycoprotein e2 (47 kDa, Protein from Venezuelan equine encephalitis virus (strain TC-83))
- Venezuelan equine encephalitis virus (strain tc-83) (Virus from Venezuelan equine encephalitis virus (strain TC-83))
- Assembly protein e3 (6 kDa, Protein from Venezuelan equine encephalitis virus (strain TC-83))
- Spike glycoprotein e1 (47 kDa, Protein from Venezuelan equine encephalitis virus (strain TC-83))
- Capsid protein (30 kDa, Protein from Venezuelan equine encephalitis virus (strain TC-83))