Resolution: 3.03 Å
EM Method: Single-particle
Fitted PDBs: 8b01
Q-score: 0.539
Davies JS, Currie MJ, North RA, Scalise M, Wright JD, Copping JM, Remus DM, Gulati A, Morado DR, Jamieson SA, Newton-Vesty MC, Abeysekera GS, Ramaswamy S, Friemann R, Wakatsuki S, Allison JR, Indiveri C, Drew D, Mace PD, Dobson RCJ
Nat Commun (2023) 14 pp. 1120-1120 [ Pubmed: 36849793 DOI: doi:10.1038/s41467-023-36590-1 ]
- Hexane (86 Da, Ligand)
- Putative trap-type c4-dicarboxylate transport system, large permease component (45 kDa, Protein from Photobacterium profundum SS9)
- Megabody (Complex from Helicobacter pylori)
- Megabody c7hopq (54 kDa, Protein from synthetic construct)
- N-octane (114 Da, Ligand)
- Phosphatidylethanolamine (734 Da, Ligand)
- Sodium ion (22 Da, Ligand)
- Siaqm (Complex from Photobacterium profundum)
- Decane (142 Da, Ligand)
- Tridecane (184 Da, Ligand)
- Putative trap-type c4-dicarboxylate transport system, small permease component (19 kDa, Protein from Photobacterium profundum SS9)
- Siaqm with megabody (Complex)
- Docosane (310 Da, Ligand)
Cryo-EM structure of Gi-bound metabotropic glutamate receptor mGlu2
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7e9g
Q-score: 0.39
Lin S, Han S, Cai X, Tan Q, Zhou K, Wang D, Wang X, Du J, Yi C, Chu X, Dai A, Zhou Y, Chen Y, Zhou Y, Liu H, Liu J, Yang D, Wang MW, Zhao Q, Wu B
Nature (2021) 594 pp. 583-588 [ DOI: doi:10.1038/s41586-021-03495-2 Pubmed: 34135510 ]
- Dn13 (13 kDa, Protein from Lama glama)
- 1-butyl-3-chloranyl-4-(4-phenylpiperidin-1-yl)pyridin-2-one (344 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- Complex of mglu2 homodimer with heterotrimeric gi1 protein in presence of antibodies (Complex from Homo sapiens)
- Metabotropic glutamate receptor 2 (90 kDa, Protein from Homo sapiens)
- Scfv16 (27 kDa, Protein from Homo sapiens)
- (1s,2s,5r,6s)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (185 Da, Ligand)
Cryo-EM structure of LY354740-bound mGlu2 homodimer
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7epb
Q-score: 0.377
Du J, Wang D, Fan H, Xu C, Tai L, Lin S, Han S, Tan Q, Wang X, Xu T, Zhang H, Chu X, Yi C, Liu P, Wang X, Zhou Y, Pin JP, Rondard P, Liu H, Liu J, Sun F, Wu B, Zhao Q
Nature (2021) 594 pp. 589-593 [ DOI: doi:10.1038/s41586-021-03641-w Pubmed: 34135509 ]
- Ly354740-bound mglu2 homodimer (Complex from Homo sapiens)
- Metabotropic glutamate receptor 2 (94 kDa, Protein from Homo sapiens)
- (1s,2s,5r,6s)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (185 Da, Ligand)
- Anti-ron nanobody (15 kDa, Protein from Lama glama)