Vaccine-elicited human antibody 2C06 in complex with HIV-1 envelope trimer BG505 DS-SOSIP
Resolution: 2.95 Å
EM Method: Single-particle
Fitted PDBs: 8g4m
Q-score: 0.564
Wang S, Matassoli F, Zhang B, Liu T, Shen CH, Bylund T, Johnston T, Henry AR, Teng IT, Tripathi P, Becker JE, Changela A, Chaudhary R, Cheng C, Gaudinski M, Gorman J, Harris DR, Lee M, Morano NC, Novik L, O'Dell S, Olia AS, Parchment DK, Rawi R, Roberts-Torres J, Stephens T, Tsybovsky Y, Wang D, Van Wazer DJ, Zhou T, Doria-Rose NA, Koup RA, Shapiro L, Douek DC, McDermott AB, Kwong PD
Cell Rep (2023) 42 pp. 112755-112755 [ Pubmed: 37436899 DOI: doi:10.1016/j.celrep.2023.112755 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Envelope glycoprotein gp120 (52 kDa, Protein from Human immunodeficiency virus 1)
- Hiv envelope trimer in complex with three copies of antibody fab (Complex)
- Antibody light chain (23 kDa, Protein from Homo sapiens)
- Antibody heavy chain (25 kDa, Protein from Homo sapiens)
- Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
Vaccine-elicited human antibody 2C09 in complex with HIV-1 envelope trimer BG505 DS-SOSIP
Resolution: 2.81 Å
EM Method: Single-particle
Fitted PDBs: 8g4t
Q-score: 0.56
Wang S, Matassoli F, Zhang B, Liu T, Shen CH, Bylund T, Johnston T, Henry AR, Teng IT, Tripathi P, Becker JE, Changela A, Chaudhary R, Cheng C, Gaudinski M, Gorman J, Harris DR, Lee M, Morano NC, Novik L, O'Dell S, Olia AS, Parchment DK, Rawi R, Roberts-Torres J, Stephens T, Tsybovsky Y, Wang D, Van Wazer DJ, Zhou T, Doria-Rose NA, Koup RA, Shapiro L, Douek DC, McDermott AB, Kwong PD
Cell Rep (2023) 42 pp. 112755-112755 [ Pubmed: 37436899 DOI: doi:10.1016/j.celrep.2023.112755 ]
- Fab 2c09 heavy chain (24 kDa, Protein from Homo sapiens)
- Fab 2c09 light chain (23 kDa, Protein from Homo sapiens)
- Envelope glycoprotein bg505 ds-sosip gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Envelope glycoprotein bg505 ds-sosip gp120 (52 kDa, Protein from Human immunodeficiency virus 1)
- Hiv envelope trimer in complex with three copies of antibody fab (Complex)
Easterhoff D, Moody MA, Fera D, Cheng H, Ackerman M, Wiehe K, Saunders KO, Pollara J, Vandergrift N, Parks R, Kim J, Michael NL, O'Connell RJ, Excler JL, Robb ML, Vasan S, Rerks-Ngarm S, Kaewkungwal J, Pitisuttithum P, Nitayaphan S, Sinangil F, Tartaglia J, Phogat S, Kepler TB, Alam SM, Liao HX, Ferrari G, Seaman MS, Montefiori DC, Tomaras GD, Harrison SC, Haynes BF
PLoS Pathog (2017) 13 pp. e1006182-e1006182 [ Pubmed: 28235027 DOI: doi:10.1371/journal.ppat.1006182 ]
- Dh576 fab light chain (Protein from Homo sapiens)
- Ch505 transmitted founder envelope (Complex from Homo sapiens)
- Hiv-1 ch505 transmitted founder sosip.664 env trimer in complex with the dh576 fab from the rv305 trial (50 kDa, Complex from Homo sapiens)
- Hiv envelope (Protein from Homo sapiens)
- Dh576 fab heavy chain (Protein from Homo sapiens)
- Dh576 fab (Complex from Homo sapiens)