Structure of CD163 in complex with Hb-Hp
Resolution: 3.11 Å
EM Method: Single-particle
Fitted PDBs: 8xmp
Q-score: 0.488
To Be Published
- Isoform 2 of haptoglobin (38 kDa, Protein from Homo sapiens)
- Hemoglobin subunit beta (16 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Cd163 in complex with hb-hp (Complex from Homo sapiens)
- Hemoglobin subunit alpha (15 kDa, Protein from Homo sapiens)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Scavenger receptor cysteine-rich type 1 protein m130 (109 kDa, Protein from Homo sapiens)
Structure of dimeric CD163 in complex with Hb-Hp
Resolution: 3.21 Å
EM Method: Single-particle
Fitted PDBs: 8xmq
Q-score: 0.462
To Be Published
- Isoform 2 of haptoglobin (38 kDa, Protein from Homo sapiens)
- Dimeric cd163 in complex with hb-hp (Complex from Homo sapiens)
- Hemoglobin subunit beta (16 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Hemoglobin subunit alpha (15 kDa, Protein from Homo sapiens)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Scavenger receptor cysteine-rich type 1 protein m130 (109 kDa, Protein from Homo sapiens)
Cryo-EM structure of human CD163 SRCR2-4 in complex with haptoglobin-hemoglobin
Resolution: 3.87 Å
EM Method: Single-particle
Fitted PDBs: 9fhb
Q-score: 0.405
Etzerodt A, Mikkelsen JH, Torvund-Jensen M, Hennig D, Boesen T, Graversen JH, Moestrup SK, Kollman JM, Andersen CBF
Nat Commun (2024) 15 pp. 10871-10871 [ Pubmed: 39738064 DOI: doi:10.1038/s41467-024-55171-4 ]
- Hemoglobin subunit beta (16 kDa, Protein from Homo sapiens)
- Cd163 (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Hemoglobin subunit alpha (15 kDa, Protein from Homo sapiens)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Scavenger receptor cysteine-rich type 1 protein m130 (125 kDa, Protein from Homo sapiens)
- Haptoglobin-hemoglobin complex (Complex from Homo sapiens)
- Haptoglobin (45 kDa, Protein from Homo sapiens)
- Cd163 in complex with haptoglobin-hemoglobin (Complex)
cryo-EM structure of hemoglobin
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7xgy
Q-score: 0.407
Zheng L, Liu N, Gao X, Zhu W, Liu K, Wu C, Yan R, Zhang J, Gao X, Yao Y, Deng B, Xu J, Lu Y, Liu Z, Li M, Wei X, Wang HW, Peng H
Nat Methods (2023) 20 pp. 123-130 [ DOI: doi:10.1038/s41592-022-01693-y Pubmed: 36522503 ]
- Hemoglobin subunit alpha (15 kDa, Protein from Homo sapiens)
- Hemoglobin subunit beta (16 kDa, Protein from Homo sapiens)
- Hemoglobin (Complex from Homo sapiens)
- Protoporphyrin ix containing fe (616 Da, Ligand)
Human carboxyhemoglobin bound to Staphylococcus aureus hemophore IsdB - 1:1 complex
Resolution: 3.62 Å
EM Method: Single-particle
Fitted PDBs: 7pcq
Q-score: 0.322
De Bei O, Marchetti M, Ronda L, Gianquinto E, Lazzarato L, Chirgadze DY, Hardwick SW, Cooper LR, Spyrakis F, Luisi BF, Campanini B, Bettati S
PNAS (2022) 119 pp. e2116708119-e2116708119 [ Pubmed: 35357971 DOI: doi:10.1073/pnas.2116708119 ]
- Iron-regulated surface determinant protein b (Complex from Staphylococcus aureus subsp. aureus MW2)
- Hemoglobin subunit alpha (15 kDa, Protein from Homo sapiens)
- Iron-regulated surface determinant protein b (43 kDa, Protein from Staphylococcus aureus subsp. aureus MW2)
- Hemoglobin subunit beta (15 kDa, Protein from Homo sapiens)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Human carboxyhemoglobin bound to staphylococcus aureus hemophore isdb - 1:1 complex (108 kDa, Complex)
- Hemoglobin (Complex from Homo sapiens)
3.6 A structure of the human hemoglobin
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7vde
Q-score: 0.448
Fan H, Wang B, Zhang Y, Zhu Y, Song B, Xu H, Zhai Y, Qiao M, Sun F
Nat Commun (2021) 12 pp. 7257-7257 [ DOI: doi:10.1038/s41467-021-27596-8 Pubmed: 34907237 ]
- Hemoglobin subunit alpha (15 kDa, Protein from Homo sapiens)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Hemoglobin subunit beta (16 kDa, Protein from Homo sapiens)
- Human hemoglobin (64 kDa, Complex from Homo sapiens)
Single-particle cryo-EM reconstruction of human methemoglobin using 200 keV, state 2
Nat Commun (2019) 10 pp. 1032-1032 [ Pubmed: 30833564 DOI: doi:10.1038/s41467-019-08991-8 ]
- Hemoglobin subunit beta (15 kDa, Protein from Homo sapiens)
- Human methemoglobin (64 kDa, Complex from Homo sapiens)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Hemoglobin subunit alpha (14 kDa, Protein from Homo sapiens)
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 5m3l
Q-score: 0.409
Afanasyev P, Linnemayr-Seer C, Ravelli RBG, Matadeen R, De Carlo S, Alewijnse B, Portugal RV, Pannu NS, Schatz M, van Heel M
To Be Published
- Hemoglobin (3 MDa, Protein from Lumbricus terrestris)
- Hemoglobin purified from lumbricus terrestris (3 MDa, Sample)
Khoshouei M, Radjainia M, Baumeister W, Danev R
Nat Commun (2017) 8 pp. 16099-16099 [ DOI: doi:10.1038/ncomms16099 Pubmed: 28665412 ]
- Hemoglobin (Complex from Homo sapiens)
Cryo-EM asymmetric recontsruction of haemoglobin at 3.4 A determined with the Volta phase plate
Khoshouei M, Radjainia M, Baumeister W, Danev R
Nat Commun (2017) 8 pp. 16099-16099 [ DOI: doi:10.1038/ncomms16099 Pubmed: 28665412 ]
- Hemoglobin (Complex from Homo sapiens)