Structure of CD163 in complex with Hb-Hp
Resolution: 3.11 Å
EM Method: Single-particle
Fitted PDBs: 8xmp
Q-score: 0.488
To Be Published
- Isoform 2 of haptoglobin (38 kDa, Protein from Homo sapiens)
- Hemoglobin subunit alpha (15 kDa, Protein from Homo sapiens)
- Hemoglobin subunit beta (16 kDa, Protein from Homo sapiens)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Scavenger receptor cysteine-rich type 1 protein m130 (109 kDa, Protein from Homo sapiens)
- Cd163 in complex with hb-hp (Complex from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of dimeric CD163 in complex with Hb-Hp
Resolution: 3.21 Å
EM Method: Single-particle
Fitted PDBs: 8xmq
Q-score: 0.462
To Be Published
- Dimeric cd163 in complex with hb-hp (Complex from Homo sapiens)
- Isoform 2 of haptoglobin (38 kDa, Protein from Homo sapiens)
- Hemoglobin subunit alpha (15 kDa, Protein from Homo sapiens)
- Hemoglobin subunit beta (16 kDa, Protein from Homo sapiens)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Scavenger receptor cysteine-rich type 1 protein m130 (109 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of human CD163 SRCR2-4 in complex with haptoglobin-hemoglobin
Resolution: 3.87 Å
EM Method: Single-particle
Fitted PDBs: 9fhb
Q-score: 0.405
Etzerodt A, Mikkelsen JH, Torvund-Jensen M, Hennig D, Boesen T, Graversen JH, Moestrup SK, Kollman JM, Andersen CBF
Nat Commun (2024) 15 pp. 10871-10871 [ DOI: doi:10.1038/s41467-024-55171-4 Pubmed: 39738064 ]
- Cd163 (Complex from Homo sapiens)
- Scavenger receptor cysteine-rich type 1 protein m130 (125 kDa, Protein from Homo sapiens)
- Cd163 in complex with haptoglobin-hemoglobin (Complex)
- Haptoglobin (45 kDa, Protein from Homo sapiens)
- Hemoglobin subunit alpha (15 kDa, Protein from Homo sapiens)
- Hemoglobin subunit beta (16 kDa, Protein from Homo sapiens)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Haptoglobin-hemoglobin complex (Complex from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
cryo-EM structure of hemoglobin
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7xgy
Q-score: 0.407
Zheng L, Liu N, Gao X, Zhu W, Liu K, Wu C, Yan R, Zhang J, Gao X, Yao Y, Deng B, Xu J, Lu Y, Liu Z, Li M, Wei X, Wang HW, Peng H
Nat Methods (2023) 20 pp. 123-130 [ DOI: doi:10.1038/s41592-022-01693-y Pubmed: 36522503 ]
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Hemoglobin (Complex from Homo sapiens)
- Hemoglobin subunit beta (16 kDa, Protein from Homo sapiens)
- Hemoglobin subunit alpha (15 kDa, Protein from Homo sapiens)
Human carboxyhemoglobin bound to Staphylococcus aureus hemophore IsdB - 1:1 complex
Resolution: 3.62 Å
EM Method: Single-particle
Fitted PDBs: 7pcq
Q-score: 0.322
De Bei O, Marchetti M, Ronda L, Gianquinto E, Lazzarato L, Chirgadze DY, Hardwick SW, Cooper LR, Spyrakis F, Luisi BF, Campanini B, Bettati S
PNAS (2022) 119 pp. e2116708119-e2116708119 [ Pubmed: 35357971 DOI: doi:10.1073/pnas.2116708119 ]
- Human carboxyhemoglobin bound to staphylococcus aureus hemophore isdb - 1:1 complex (108 kDa, Complex)
- Hemoglobin subunit alpha (15 kDa, Protein from Homo sapiens)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Iron-regulated surface determinant protein b (43 kDa, Protein from Staphylococcus aureus subsp. aureus MW2)
- Hemoglobin subunit beta (15 kDa, Protein from Homo sapiens)
- Iron-regulated surface determinant protein b (Complex from Staphylococcus aureus subsp. aureus MW2)
- Hemoglobin (Complex from Homo sapiens)
3.6 A structure of the human hemoglobin
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7vde
Q-score: 0.448
Fan H, Wang B, Zhang Y, Zhu Y, Song B, Xu H, Zhai Y, Qiao M, Sun F
Nat Commun (2021) 12 pp. 7257-7257 [ Pubmed: 34907237 DOI: doi:10.1038/s41467-021-27596-8 ]
- Human hemoglobin (64 kDa, Complex from Homo sapiens)
- Hemoglobin subunit alpha (15 kDa, Protein from Homo sapiens)
- Hemoglobin subunit beta (16 kDa, Protein from Homo sapiens)
- Protoporphyrin ix containing fe (616 Da, Ligand)
Single-particle cryo-EM reconstruction of human methemoglobin using 200 keV, state 2
Nat Commun (2019) 10 pp. 1032-1032 [ Pubmed: 30833564 DOI: doi:10.1038/s41467-019-08991-8 ]
- Hemoglobin subunit beta (15 kDa, Protein from Homo sapiens)
- Human methemoglobin (64 kDa, Complex from Homo sapiens)
- Hemoglobin subunit alpha (14 kDa, Protein from Homo sapiens)
- Protoporphyrin ix containing fe (616 Da, Ligand)
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 5m3l
Q-score: 0.409
Afanasyev P, Linnemayr-Seer C, Ravelli RBG, Matadeen R, De Carlo S, Alewijnse B, Portugal RV, Pannu NS, Schatz M, van Heel M
To Be Published
- Hemoglobin (3 MDa, Protein from Lumbricus terrestris)
- Hemoglobin purified from lumbricus terrestris (3 MDa, Sample)